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Acknowledgement
This thesis can only be finished with the help of everyone I met along this journey.
Firstly, I want to thank my supervisor Prof. Takayuki Uchihashi for his enormous support
in research and living in Japan and guided me toward a meaningful destination.
I want to thank Prof. Christian Ganser and Dr. Shigetaka Nishiguchi (ExCELLs, NINS)
for their thoughtful advice throughout the study. The discussion with you is always
refreshing.
I want to thank Prof. Tadayuki Ogawa (The University of Tokyo) for his precious advice
on the microtubule experiment and Prof. Tetsuya Takeda (Okayama University) for his
crucial help on the BIN1 experiment.
I want to thank Prof. Ryota Iino, Prof. Akihiro Otomo and Dr. Akasit Visootsat (IMS,
NINS) for supporting tubulin preparation and academic discussion.
I want to thank Prof. Chi-Ying Lin (National Taiwan University of Science and
Technology), Prof. En-Te Hwu (Technical University of Denmark), and Prof. Ing-Shouh
Hwang (Academia Sinica) for their encouragement. Your words are always warm and
motivational.
I want to thank Prof. Michio Homma and Dr. Yuichiro Nishizawa for their enthusiastic
and altruistic help.
To all the lab members past and present in D Lab at Nagoya University, thank you for all
the help with the life and study in Japan.
I want to thank the Ministry of Education of Taiwan for the aid for studying in Japan.
To my family, Mom, Dad, Feng-Tze, Yu-Wen, I appreciate your understanding and belief
as well as nourishing my mind.
Finally, Shu-Wen Wang, thank you for always being with me. There is never enough
words to express my appreciation to every challenge we have overcome together.
Thank you.
91
Publication List
1. Feng-Yueh Chan, Ryo Kurosaki, Christian Ganser, Tetsuya Takeda, and Takayuki
Uchihashi , "Tip-scan high-speed atomic force microscopy with a uniaxial substrate
stretching device for studying dynamics of biomolecules under mechanical stress",
Review of Scientific Instruments 93, 113703 (2022), DOI: 10.1063/5.0111017
92
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