Bashutski, J. D., & Wang, H. L. (2009). Periodontal and endodontic regeneration. Journal of Endodontics, 35(3), 321–328. https://doi.org/10.1016/j.joen.2008.11.023
Beertsen, W., McCulloch, C. A., & Sodek, J. (1997). The periodontal ligament: a unique, multifunctional connective tissue. Periodontology 2000, 13, 20–40. https://doi.org/ 10.1111/j.1600-0757.1997.tb00094.x
Brent, A. E., Schweitzer, R., & Tabin, C. J. (2003). A somitic compartment of tendon progenitors. Cell, 113(2), 235–248. https://doi.org/10.1016/s0092-8674(03)00268- x
Chen, Y. R., Meyer, C. F., & Tan, T. H. (1996). Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. The Journal of Biological Chemistry, 271(2), 631–634. https://doi.org/10.1074/jbc.271.2.631
Davis, R. J. (2000). Signal transduction by the JNK group of MAP kinases. Cell, 103(2), 239–252. https://doi.org/10.1016/s0092-8674(00)00116-1
Freeman, E. (1994). Peridontium. In A. R. Ten Cate (Ed.), Oral Histology: Development, Structure, and Function (pp. 276–312). St. Louis: Mosby.
Fujii, M., Takeda, K., Imamura, T., Aoki, H., Sampath, T. K., Enomoto, S., … Miyazono, K. (1999). Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Molecular Biology of the Cell, 10(11), 3801–3813. https://doi.org/10.1091/mbc.10.11.3801
Fujii, S., Maeda, H., Wada, N., Tomokiyo, A., Saito, M., & Akamine, A. (2008). Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo. Journal of Cellular Physiology, 215(3), 743–749. https://doi.org/ 10.1002/jcp.21359
Gautschi, O. P., Frey, S. P., & Zellweger, R. (2007). Bone morphogenetic proteins in clinical applications. ANZ Journal of Surgery, 77(8), 626–631. https://doi.org/ 10.1111/j.1445-2197.2007.04175.x
Ge, C., Xiao, G., Jiang, D., & Franceschi, R. T. (2007). Critical role of the extracellular signal-regulated kinase-MAPK pathway in osteoblast differentiation and skeletal development. The Journal of Cell Biology, 176(5), 709–718. https://doi.org/10.1083/ jcb.200610046
Graves, D. T., & Cochran, D. L. (1994). Periodontal regeneration with polypeptide growth factors. Current Opinion in Periodontology, 178–186.
Guo, C., Wang, S. L., Xu, S. T., Wang, J. G., & Song, G. H. (2015). SP600125 reduces lipopolysaccharide-induced apoptosis and restores the early-stage differentiation of osteoblasts inhibited by LPS through the MAPK pathway in MC3T3-E1 cells. International Journal of Molecular Medicine, 35(5), 1427–1434. https://doi.org/ 10.3892/ijmm.2015.2130
Guo, Y. L., Baysal, K., Kang, B., Yang, L. J., & Williamson, J. R. (1998). Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. The Journal of Biological Chemistry, 273(7), 4027–4034. https://doi.org/10.1074/jbc.273.7.4027
Hasegawa, D., Hasegawa, K., Kaneko, H., Yoshida, S., Mitarai, H., Arima, M., … Maeda, H. (2020). MEST regulates the stemness of human periodontal ligament stem cells. Stem Cells International, 2020, Article 9672673. https://doi.org/10.1155/ 2020/9672673
Hasegawa, D., Wada, N., Maeda, H., Yoshida, S., Mitarai, H., Tomokiyo, A., … Akamine, A. (2015). Wnt5a induces collagen production by human periodontal ligament cells through TGFβ1-mediated upregulation of periostin expression. Journal of Cellular Physiology, 230(11), 2647–2660. https://doi.org/10.1002/jcp.24950
Hasegawa, D., Wada, N., Yoshida, S., Mitarai, H., Arima, M., Tomokiyo, A., … Maeda, H. (2018). Wnt5a suppresses osteoblastic differentiation of human periodontal ligament stem cell-like cells via Ror2/JNK signaling. Journal of Cellular Physiology, 233(2), 1752–1762. https://doi.org/10.1002/jcp.26086
Horiuchi, K., Amizuka, N., Takeshita, S., Takamastu, H., Katsuura, M., Ozawa, H., … Kudo, A. (1999). Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. Journal of Bone and Mineral Research, 14(7), 1239–1249. https://doi.org/10.1359/jbmr.1999.14.7.1239
Huang, Y. F., Lin, J. J., Lin, C. H., Su, Y., & Hung, S. C. (2012). c-Jun N-terminal kinase 1 negatively regulates osteoblastic differentiation induced by BMP2 via phosphorylation of Runx2 at Ser104. Journal of Bone and Mineral Research, 27(5), 1093–1105. https://doi.org/10.1002/jbmr.1548
Ichiyama, K., Sekiya, T., Inoue, N., Tamiya, T., Kashiwagi, I., Kimura, A., … Yoshimura, A. (2011). Transcription factor Smad-independent T helper 17 cell induction by transforming-growth factor-β is mediated by suppression of eomesodermin. Immunity, 34(5), 741–754. https://doi.org/10.1016/j. immuni.2011.02.021
Iwasaki, K., Akazawa, K., Nagata, M., Komaki, M., Honda, I., Morioka, C., … Morita, I. (2019). The fate of transplanted periodontal ligament stem cells in surgically created periodontal defects in rats. International Journal of Molecular Sciences, 20(1), 192. https://doi.org/10.3390/ijms20010192
Kawai, S., Faucheu, C., Gallea, S., Spinella-Jaegle, S., Atfi, A., Baron, R., & Roman, S. R. (2000). Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity. Biochemical and Biophysical Research Communications, 271(3), 682–687. https://doi. org/10.1006/bbrc.2000.2704
King, G. N., King, N., Cruchley, A. T., Wozney, J. M., & Hughes, F. J. (1997). Recombinant human bone morphogenetic protein-2 promotes wound healing in rat periodontal fenestration defects. Journal of Dental Research, 76(8), 1460–1470. https://doi.org/10.1177/00220345970760080801
Kyriakis, J. M., & Avruch, J. (2001). Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiological Reviews, 81(2), 807–869. https://doi.org/10.1152/physrev.2001.81.2.807
Maeda, H., Wada, N., Nakamuta, H., & Akamine, A. (2004). Human periapical granulation tissue contains osteogenic cells. Cell and Tissue Research, 315(2), 203–208. https://doi.org/10.1007/s00441-003-0832-z
McKay, W. F., Peckham, S. M., & Badura, J. M. (2007). A comprehensive clinical review of recombinant human bone morphogenetic protein-2 (INFUSE Bone Graft). International Orthopaedics, 31(6), 729–734. https://doi.org/10.1007/s00264-007-0418-6
Miyazono, K., Maeda, S., & Imamura, T. (2005). BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk. Cytokine & Growth Factor Reviews, 16(3), 251–263. https://doi.org/10.1016/j.cytogfr.2005.01.009
Murakami, S. (2011). Periodontal tissue regeneration by signaling molecule(s): what role does basic fibroblast growth factor (FGF-2) have in periodontal therapy? Periodontology 2000, 56(1), 188–208. https://doi.org/10.1111/j.1600- 0757.2010.00365.x
Murakami, S., Takayama, S., Kitamura, M., Shimabukuro, Y., Yanagi, K., & Ikezawa, K. (2003). Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogs. Journal of Periodontal Research, 38(1), 97–103. https://doi.org/10.1034/j.1600- 0765.2003.00640.x
Nagata, M., Iwasaki, K., Akazawa, K., Komaki, M., Yokoyama, N., Izumi, Y., & Morita, I. (2017). Conditioned medium from periodontal ligament stem cells enhances periodontal regeneration. Tissue Engineering Part A, 23(9–10), 367–377. https://doi. org/10.1089/ten.TEA.2016.0274
Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., & de Crombrugghe, B. (2002). The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell, 108(1), 17–29. https://doi.org/10.1016/s0092-8674(01)00622-5
Nishimura, R., Hata, K., Ikeda, F., Ichida, F., Shimoyama, A., Matsubara, T., … Yoneda, T. (2008). Signal transduction and transcriptional regulation during mesenchymal cell differentiation. Journal of Bone and Mineral Metabolism, 26(3), 203–212. https://doi.org/10.1007/s00774-007-0824-2
Nishimura, R., Kato, Y., Chen, D., Harris, S. E., Mundy, G. R., & Yoneda, T. (1998). Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12. The Journal of Biological Chemistry, 273(4), 1872–1879. https://doi.org/10.1074/ jbc.273.4.1872
Papadopoulou, A., Iliadi, A., Eliades, T., & Kletsas, D. (2017). Early responses of human periodontal ligament fibroblasts to cyclic and static mechanical stretching. European Journal of Orthodontics, 39(3), 258–263.
Po¨schke, A., Kra¨hling, B., Failing, K., & Staszyk, C. (2018). Molecular characteristics of the equine periodontal ligament. Frontiers in Veterinary Science, 11(4), 235. https:// doi.org/10.3389/fvets.2017.00235
Rath, B., Nam, J., Deschner, J., Schaumburger, J., Tingart, M., Gr¨assel, S., … Agarwal, S. (2011). Biomechanical forces exert anabolic effects on osteoblasts by activation of SMAD 1/5/8 through type 1 BMP receptor. Biorheology, 48(1), 37–48. https://doi. org/10.3233/BIR-2011-0580
Romanos, G. E., Asnani, K. P., Hingorani, D., & Deshmukh, V. L. (2013). PERIOSTIN: role in formation and maintenance of dental tissues. Journal of Cellular Physiology, 229 (5), 1–5. https://doi.org/10.1002/jcp.24491
Seino, M., Okada, M., Sakaki, H., Takeda, H., Watarai, H., Suzuki, S., … Kitanaka, C. (2016). Time-staggered inhibition of JNK effectively sensitizes chemoresistant ovarian cancer cells to cisplatin and paclitaxel. Oncology Reports, 35(1), 593–601. https://doi.org/10.3892/or.2015.4377
Seo, B. M., Miura, M., Gronthos, S., Bartold, P. M., Batouli, S., Brahim, J., … Shi, S. (2004). Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet, 364(9429), 149–155. https://doi.org/10.1016/S0140-6736(04)16627-0
Takayama, S., Murakami, S., Shimabukuro, Y., Kitamura, M., & Okada, H. (2001). Periodontal regeneration by FGF-2 (bFGF) in primate models. Journal of Dental Research, 80(12), 2075–2079. https://doi.org/10.1177/00220345010800121001
Wang, E. A. (1993). Bone morphogenetic proteins (BMPs): therapeutic potential in healing bony defects. Trends in Biotechnology, 11(9), 379–383. https://doi.org/ 10.1016/0167-7799(93)90096-R
Wang, M., Li, J., Ye, Y., He, S., & Song, J. (2020). SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro. Differentiation, 111, 1–11. https://doi.org/10.1016/j.diff.2019.10.003
Weston, C. R., & Davis, R. J. (2002). The JNK signal transduction pathway. Current Opinion in Genetics & Development, 12(1), 14–21. https://doi.org/10.1016/s0959- 437x(01)00258-1
Woo, E. J. (2012). Adverse events reported after the use of recombinant human bone morphogenetic protein 2. Journal of Oral and Maxillofacial Surgery, 70(4), 765–767. https://doi.org/10.1016/j.joms.2011.09.008
Wu, D. T., Bitzer, M., Ju, W., Mundel, P., & Bo¨ttinger, E. P. (2005). TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. Journal of the American Society of Nephrology, 16(11), 3211–3221. https://doi.org/10.1681/ASN.2004121055
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