Waist-to-height Ratio and Type 2 Diabetes Among Japanese men: A Longitudinal Study from the Oroshisho Study

概要

Background: Waist-to-height (WHTR) can be a useful potential predictor of type 2 diabetes (T2DM).
We the association between WHTR and the incidence of T2DM.
Methods: This longitudinal study was conducted in 692 nondiabetic Japanese men aged to 20 to 78
years, using Data came from the Oroshisho Survey, 2008-2011. The objective of this study was to
evaluate the association between waist-to-height (WHTR) and the incidence of T2DM,
and to compare the associations of three obesity anthropometric indices, including waist-to-height
(WHTR), waist circumference (WC) and body-mass index (BMI) with T2DM.A logistic regression model
was used to assess the relationship between excess WHTR and T2DM.For the analysis of WHTR, WC,
and BMI levels, individuals were first divided into quartiles (Q1, Q2, Q3, and Q4) based on the levels
at baseline. All participants were performed according to the WHTR levels of quartiles (WHTR<0.4611,
0.4611≤WHTR<0.4955, 0.4955≤WHTR<0.5320, WHTR≥0.5320). WC levels of quartiles (WC<78, 78
≤WC<84, 84≤WC<90, WC≥90), and BMI levels of quartiles (BMI<21.5, 21.5≤ BMI< 23.5,
23.5≤BMI<25.8, BMI≥25.8). The reference group was the participants between WHTR<0.4611, WC<78,
and BMI<21.5.
Results: During the entire study period, 97 participants developed diabetes. This prospective cohort
study found that elevated WHTR was significantly associated with an increased risk of T2DM.The
odds ratios (ORs) and 95% confidence intervals (CIs)of the incidence of T2DM according to WHTR, WC,
BMI measurement. Compared with the lowest WHTR, WC, and BMI quartiles, ORs of the highest
quartiles were 3.20(95%CI, 1.59-6.87; p-trend=0.002), 2.38 (95%CI, 1.21-4.66; p-trend=0.043),
2.21(95%CI, 1.15-4.26; p-trend=0.021). ...