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謝辞
本研究を行うにあたり、終始私の意思を尊重してくださった村上洋太先生に厚く御礼申
し上げます。
抗 Cnp1 抗体を石井浩二郎博士から、抗 H3K9me 抗体を浦野健博士から、抗 H3K14ac
抗体を木村宏博士から分与して頂きました。セントロメア境界領域に ura4+が挿入された分
裂酵母株および Cnp1 過剰発現プラスミドを Robin Allshire 博士から、snf21-36 変異株を
太田邦史博士から分与して頂きました。次世代シーケンシングを鈴木穣博士に、次世代シー
ケンシングデータの解析サポートを加藤太陽博士に行って頂きました。本研究のさきがけ
となる実験を中川浩実博士に行って頂きました。皆様のご協力に感謝を申し上げます。
本研究について議論して下さった高橋正行博士、高畑信也博士、佐藤勇太博士、浅沼高寛
氏に感謝を申し上げます。
最後に、私の自由を尊重し見守ってくれた家族と友人達に心から感謝します。
本学位論文は以下の学術論文の内容に基づいて書かれたものである。
The chromatin remodeler RSC prevents ectopic CENP-A propagation into pericentromeric
heterochromatin at the chromatin boundary
Satoru Tsunemine, Hiromi Nakagawa, Yutaka Suzuki and Yota Murakami
Nucleic Acids Research, Volume 50, Issue 19, 28 October 2022, Pages 10914-10928.
61
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