Akwii RG, Sajib MS, Zahra FT, Mikelis CM (2019) Role of Angiopoietin-2 in
Vascular Physiology and Pathophysiology. Cells 8
Bertelmann T, Spychalska M, Kohlberger L, Strodthoff S, Witteborn M, Kicova N,
Sachs U, Irle S, Mennel S (2013) Intracameral concentrations of the fibrinolytic
system components in patients with age-related macular degeneration. Graefes
Arch Clin Exp Ophthalmol 251: 2697-2704
Cabral T, Lima LH, Mello LGM, Polido J, Correa É, Oshima A, Duong J,
Serracarbassa P, Regatieri CV, Mahajan VB et al (2018) Bevacizumab Injection in
Patients with Neovascular Age-Related Macular Degeneration Increases
Angiogenic Biomarkers. Ophthalmol Retina 2: 31-37
Cao C, Lawrence DA, Li Y, Von Arnim CA, Herz J, Su EJ, Makarova A, Hyman
BT, Strickland DK, Zhang L (2006) Endocytic receptor LRP together with tPA and
PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J 25: 18601870
Caspi RR, Roberge FG, Chan CC, Wiggert B, Chader GJ, Rozenszajn LA, Lando
Z, Nussenblatt RB (1988) A new model of autoimmune disease. Experimental
autoimmune uveoretinitis induced in mice with two different retinal antigens. J
Immunol 140: 1490-1495
Chan CC, Mochizuki M, Palestine AG, BenEzra D, Gery I, Nussenblatt RB (1985)
Kinetics of T-lymphocyte subsets in the eyes of Lewis rats with experimental
autoimmune uveitis. Cell Immunol 96: 430-434
Chi YF, Chai JK, Yu YM, Luo HM, Zhang QX, Feng R (2015) Association
between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely
burned patients. Genet Mol Res 14: 10081-10086
Choe JY, Park SH, Kim SK (2010) Serum angiopoietin-1 level is increased in
patients with Behçet's disease. Joint Bone Spine 77: 340-344
Cravens PD, Lipsky PE (2002) Dendritic cells, chemokine receptors and
autoimmune inflammatory diseases. Immunol Cell Biol 80: 497-505
Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno
J, Radziejewski C, Maisonpierre PC et al (1996) Isolation of angiopoietin-1, a
ligand for the TIE2 receptor, by secretion-trap expression cloning. Cell 87: 11611169
De Kozak Y, FRE, Usui M, Faure JP (1976) [Experimental autoimmune
47
uveoretinitis. Ultrastructure of chorioretinal lesions induced in guinea pigs by
immunization against the outer rods of the bovine retina]. Arch Ophtalmol (Paris)
36: 231-248
de Sá MC, Simão ANC, de Medeiros FA, Iriyoda TMV, Costa NT, Alfieri DF,
Flauzino T, Sekiguchi BA, Lozovoy MAB, Reiche EMV et al (2018) Cell
adhesion molecules and plasminogen activator inhibitor type-1 (PAI-1) in patients
with rheumatoid arthritis: influence of metabolic syndrome. Clin Exp Med 18:
495-504
De Taeye B, Smith LH, Vaughan DE (2005) Plasminogen activator inhibitor-1: a
common denominator in obesity, diabetes and cardiovascular disease. Curr Opin
Pharmacol 5: 149-154
Degryse B, Neels JG, Czekay RP, Aertgeerts K, Kamikubo Y, Loskutoff DJ (2004)
The low density lipoprotein receptor-related protein is a motogenic receptor for
plasminogen activator inhibitor-1. J Biol Chem 279: 22595-22604
Dick AD, Forrester JV, Liversidge J, Cope AP (2004) The role of tumour necrosis
factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU). Prog Retin
Eye Res 23: 617-637
Dong Z, Iwata D, Kitaichi N, Takeuchi M, Sato M, Endo N, Iwabuchi K, Ando R,
Fukuhara J, Kinoshita S et al (2014) Amelioration of experimental autoimmune
uveoretinitis by inhibition of glyceraldehyde-derived advanced glycation endproduct formation. J Leukoc Biol 96: 1077-1085
East E, Gverić D, Baker D, Pryce G, Lijnen HR, Cuzner ML (2008) Chronic
relapsing experimental allergic encephalomyelitis (CREAE) in plasminogen
activator inhibitor-1 knockout mice: the effect of fibrinolysis during
neuroinflammation. Neuropathol Appl Neurobiol 34: 216-230
Fearon U, Griosios K, Fraser A, Reece R, Emery P, Jones PF, Veale DJ (2003)
Angiopoietins, growth factors, and vascular morphology in early arthritis. J
Rheumatol 30: 260-268
Felcht M, Luck R, Schering A, Seidel P, Srivastava K, Hu J, Bartol A, Kienast Y,
Vettel C, Loos EK et al (2012) Angiopoietin-2 differentially regulates
angiogenesis through TIE2 and integrin signaling. J Clin Invest 122: 1991-2005
Fiedler U, Reiss Y, Scharpfenecker M, Grunow V, Koidl S, Thurston G, Gale NW,
Witzenrath M, Rosseau S, Suttorp N et al (2006) Angiopoietin-2 sensitizes
endothelial cells to TNF-alpha and has a crucial role in the induction of
inflammation. Nat Med 12: 235-239
48
Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, Schmidt JM, Kriz W,
Thurston G, Augustin HG (2004) The Tie-2 ligand angiopoietin-2 is stored in and
rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
Blood 103: 4150-4156
Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, McClain J, Martin C, Witte
C, Witte MH, Jackson D et al (2002) Angiopoietin-2 is required for postnatal
angiogenesis and lymphatic patterning, and only the latter role is rescued by
Angiopoietin-1. Dev Cell 3: 411-423
Glimcher LH, Kim KJ, Green I, Paul WE (1982) Ia antigen-bearing B cell tumor
lines can present protein antigen and alloantigen in a major histocompatibility
complex-restricted fashion to antigen-reactive T cells. J Exp Med 155: 445-459
Gupta KK, Xu Z, Castellino FJ, Ploplis VA (2016) Plasminogen activator
inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4.
Biochem Biophys Res Commun 477: 503-508
Hah YS, Koh YJ, Lim HS, Kim HO, Cheon YH, Noh HS, Jang KY, Lee SY, Lee
GM, Koh GY et al (2013) Double-antiangiogenic protein DAAP targeting
vascular endothelial growth factor A and angiopoietins attenuates collageninduced arthritis. Arthritis Res Ther 15: R85
Hakanpaa L, Sipila T, Leppanen VM, Gautam P, Nurmi H, Jacquemet G, Eklund
L, Ivaska J, Alitalo K, Saharinen P (2015) Endothelial destabilization by
angiopoietin-2 via integrin β1 activation. Nat Commun 6: 5962
Hammes HP, Lin J, Wagner P, Feng Y, Vom Hagen F, Krzizok T, Renner O, Breier
G, Brownlee M, Deutsch U (2004) Angiopoietin-2 causes pericyte dropout in the
normal retina: evidence for involvement in diabetic retinopathy. Diabetes 53:
1104-1110
Hanahan D (1997) Signaling vascular morphogenesis and maintenance. Science
277: 48-50
Heil M, Clauss M, Suzuki K, Buschmann IR, Willuweit A, Fischer S, Schaper W
(2000) Vascular endothelial growth factor (VEGF) stimulates monocyte migration
through endothelial monolayers via increased integrin expression. Eur J Cell Biol
79: 850-857
Hughes DP, Marron MB, Brindle NP (2003) The antiinflammatory endothelial
tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN2. Circ Res 92: 630-636
Ichimura A, Matsumoto S, Suzuki S, Dan T, Yamaki S, Sato Y, Kiyomoto H, Ishii
49
N, Okada K, Matsuo O et al (2013) A small molecule inhibitor to plasminogen
activator inhibitor 1 inhibits macrophage migration. Arterioscler Thromb Vasc
Biol 33: 935-942
Imhof BA, Aurrand-Lions M (2006) Angiogenesis and inflammation face off. Nat
Med 12: 171-172
Iurlaro M, Scatena M, Zhu WH, Fogel E, Wieting SL, Nicosia RF (2003) Rat
aorta-derived mural precursor cells express the Tie2 receptor and respond directly
to stimulation by angiopoietins. J Cell Sci 116: 3635-3643
Iwata D, Kitaichi N, Miyazaki A, Iwabuchi K, Yoshida K, Namba K, Ozaki M,
Ohno S, Umezawa K, Yamashita K et al (2010) Amelioration of experimental
autoimmune uveoretinitis with nuclear factor-{kappa}B Inhibitor dehydroxy
methyl epoxyquinomicin in mice. Invest Ophthalmol Vis Sci 51: 2077-2084
Iwata D, Mizuuchi K, Aoki K, Horie Y, Kase S, Namba K, Ohno S, Ishida S,
Kitaichi N (2017) Serial Frequencies and Clinical Features of Uveitis in
Hokkaido, Japan. Ocul Immunol Inflamm 25: S15-S18
Jeltsch M, Leppänen VM, Saharinen P, Alitalo K (2013) Receptor tyrosine kinasemediated angiogenesis. Cold Spring Harb Perspect Biol 5
Jeon H, Kim JH, Lee WH, Lee MS, Suk K (2012) Plasminogen activator inhibitor
type 1 regulates microglial motility and phagocytic activity. J Neuroinflammation
9: 149
Kase S, Namba K, Kanno-Okada H, Onozawa M, Hidaka D, Iwata D, Mizuuchi K,
Fukuhara T, Fukuhara J, Kitaichi N et al (2020) Immunohistochemical and
Immunocytochemical Analyses in Patients with Vitreoretinal Lymphoma. Ocul
Immunol Inflamm 28: 147-155
Khanani AM, Patel SS, Ferrone PJ, Osborne A, Sahni J, Grzeschik S, Basu K,
Ehrlich JS, Haskova Z, Dugel PU (2020) Efficacy of Every Four Monthly and
Quarterly Dosing of Faricimab vs Ranibizumab in Neovascular Age-Related
Macular Degeneration: The STAIRWAY Phase 2 Randomized Clinical Trial.
JAMA Ophthalmol 138: 964-972
Kim HB (1997) Ophthalmologic manifestation of Behçet's disease. Yonsei Med J
38: 390-394
Kitamei H, Kitaichi N, Namba K, Kotake S, Goda C, Kitamura M, Miyazaki A,
Ohno S (2009) Clinical features of intraocular inflammation in Hokkaido, Japan.
Acta Ophthalmol 87: 424-428
Kitamura M, Iwabuchi K, Kitaichi N, Kon S, Kitamei H, Namba K, Yoshida K,
50
Denhardt DT, Rittling SR, Ohno S et al (2007) Osteopontin aggravates
experimental autoimmune uveoretinitis in mice. J Immunol 178: 6567-6572
Koch S, Claesson-Welsh L (2012) Signal transduction by vascular endothelial
growth factor receptors. Cold Spring Harb Perspect Med 2: a006502
Lebas H, Guérit S, Picot A, Boulay AC, Fournier A, Vivien D, Cohen Salmon M,
Docagne F, Bardou I (2022) PAI-1 production by reactive astrocytes drives tissue
dysfibrinolysis in multiple sclerosis models. Cell Mol Life Sci 79: 323
Lee J, Park DY, Park I, Chang W, Nakaoka Y, Komuro I, Yoo OJ, Koh GY (2014)
Angiopoietin-1 suppresses choroidal neovascularization and vascular leakage.
Invest Ophthalmol Vis Sci 55: 2191-2199
Li Z, Korhonen EA, Merlini A, Strauss J, Wihuri E, Nurmi H, Antila S, Paech J,
Deutsch U, Engelhardt B et al (2020) Angiopoietin-2 blockade ameliorates
autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS.
J Clin Invest 130: 1977-1990
Luna JD, Chan CC, Derevjanik NL, Mahlow J, Chiu C, Peng B, Tobe T,
Campochiaro PA, Vinores SA (1997) Blood-retinal barrier (BRB) breakdown in
experimental autoimmune uveoretinitis: comparison with vascular endothelial
growth factor, tumor necrosis factor alpha, and interleukin-1beta-mediated
breakdown. J Neurosci Res 49: 268-280
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C,
Compton D, McClain J, Aldrich TH, Papadopoulos N et al (1997) Angiopoietin-2,
a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277: 5560
McAdam AJ, Schweitzer AN, Sharpe AH (1998) The role of B7 co-stimulation in
activation and differentiation of CD4+ and CD8+ T cells. Immunol Rev 165: 231247
Murakami M, Iwai S, Hiratsuka S, Yamauchi M, Nakamura K, Iwakura Y, Shibuya
M (2006) Signaling of vascular endothelial growth factor receptor-1 tyrosine
kinase promotes rheumatoid arthritis through activation of
monocytes/macrophages. Blood 108: 1849-1856
Nakatsuka E, Sawada K, Nakamura K, Yoshimura A, Kinose Y, Kodama M,
Hashimoto K, Mabuchi S, Makino H, Morii E et al (2017) Plasminogen activator
inhibitor-1 is an independent prognostic factor of ovarian cancer and IMD-4482, a
novel plasminogen activator inhibitor-1 inhibitor, inhibits ovarian cancer
peritoneal dissemination. Oncotarget 8: 89887-89902
51
Namba K, Ogasawara K, Kitaichi N, Matsuki N, Takahashi A, Sasamoto Y, Kotake
S, Matsuda H, Iwabuchi K, Ohno S et al (1998) Identification of a peptide
inducing experimental autoimmune uveoretinitis (EAU) in H-2Ak-carrying mice.
Clin Exp Immunol 111: 442-449
Namba K, Ogasawara K, Kitaichi N, Morohashi T, Sasamoto Y, Kotake S,
Matsuda H, Iwabuchi K, Iwabuchi C, Ohno S et al (2000) Amelioration of
experimental autoimmune uveoretinitis by pretreatment with a pathogenic peptide
in liposome and anti-CD40 ligand monoclonal antibody. J Immunol 165: 29622969
Ng DS, Yip YW, Bakthavatsalam M, Chen LJ, Ng TK, Lai TY, Pang CP, Brelén
ME (2017) Elevated angiopoietin 2 in aqueous of patients with neovascular age
related macular degeneration correlates with disease severity at presentation. Sci
Rep 7: 45081
Nussenblatt RB, Kuwabara T, de Monasterio FM, Wacker WB (1981) S-antigen
uveitis in primates. A new model for human disease. Arch Ophthalmol 99: 10901092
Ohta K, Yamagami S, Wiggert B, Dana MR, Streilein JW (2002) Chemokine gene
expression in iris-ciliary body during experimental autoimmune uveoretinitis.
Curr Eye Res 24: 451-457
Okada AA, Goto H, Ohno S, Mochizuki M, Japan OBsDRGO (2012) Multicenter
study of infliximab for refractory uveoretinitis in Behçet disease. Arch
Ophthalmol 130: 592-598
Oshima Y, Oshima S, Nambu H, Kachi S, Hackett SF, Melia M, Kaleko M,
Connelly S, Esumi N, Zack DJ et al (2004) Increased expression of VEGF in
retinal pigmented epithelial cells is not sufficient to cause choroidal
neovascularization. J Cell Physiol 201: 393-400
Oztürk MA, Ertenli I, Kiraz S, C
Haznedaroğlu I, Celik I, Kirazli S, Calgüneri
M (2004) Plasminogen activator inhibitor-1 as a link between pathological
fibrinolysis and arthritis of Behçet's disease. Rheumatol Int 24: 98-102
Park HJ, Chi GY, Choi YH, Park SH (2020) Lupeol suppresses plasminogen
activator inhibitor-1-mediated macrophage recruitment and attenuates M2
macrophage polarization. Biochem Biophys Res Commun 527: 889-895
Pelisch N, Dan T, Ichimura A, Sekiguchi H, Vaughan DE, van Ypersele de Strihou
C, Miyata T (2015) Plasminogen Activator Inhibitor-1 Antagonist TM5484
Attenuates Demyelination and Axonal Degeneration in a Mice Model of Multiple
52
Sclerosis. PLoS One 10: e0124510
Peters S, Cree IA, Alexander R, Turowski P, Ockrim Z, Patel J, Boyd SR, Joussen
AM, Ziemssen F, Hykin PG et al (2007) Angiopoietin modulation of vascular
endothelial growth factor: Effects on retinal endothelial cell permeability.
Cytokine 40: 144-150
Qin Y, Zhang J, Babapoor-Farrokhran S, Applewhite B, Deshpande M, Megarity
H, Flores-Bellver M, Aparicio-Domingo S, Ma T, Rui Y et al (2022) PAI-1 is a
vascular cell-specific HIF-2-dependent angiogenic factor that promotes retinal
neovascularization in diabetic patients. Sci Adv 8: eabm1896
Rabieian R, Boshtam M, Zareei M, Kouhpayeh S, Masoudifar A, Mirzaei H
(2018) Plasminogen Activator Inhibitor Type-1 as a Regulator of Fibrosis. J Cell
Biochem 119: 17-27
Regula JT, Lundh von Leithner P, Foxton R, Barathi VA, Cheung CM, Bo Tun SB,
Wey YS, Iwata D, Dostalek M, Moelleken J et al (2016) Targeting key angiogenic
pathways with a bispecific CrossMAb optimized for neovascular eye diseases.
EMBO Mol Med 8: 1265-1288
Reiss Y, Droste J, Heil M, Tribulova S, Schmidt MHH, Schaper W, Dumont DJ,
Plate KH (2007) Angiopoietin-2 impairs revascularization after limb ischemia.
Circ Res 101: 88-96
Saharinen P, Eklund L, Alitalo K (2017) Therapeutic targeting of the angiopoietinTIE pathway. Nat Rev Drug Discov 16: 635-661
Sahni J, Patel SS, Dugel PU, Khanani AM, Jhaveri CD, Wykoff CC, Hershberger
VS, Pauly-Evers M, Sadikhov S, Szczesny P et al (2019) Simultaneous Inhibition
of Angiopoietin-2 and Vascular Endothelial Growth Factor-A with Faricimab in
Diabetic Macular Edema: BOULEVARD Phase 2 Randomized Trial.
Ophthalmology 126: 1155-1170
Sato T, Shima C, Kusaka S (2011) Vitreous levels of angiopoietin-1 and
angiopoietin-2 in eyes with retinopathy of prematurity. Am J Ophthalmol 151:
353-357.e351
Scholz A, Plate KH, Reiss Y (2015) Angiopoietin-2: a multifaceted cytokine that
functions in both angiogenesis and inflammation. Ann N Y Acad Sci 1347: 45-51
Schonthaler HB, Huggenberger R, Wculek SK, Detmar M, Wagner EF (2009)
Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse
model of psoriasis. Proc Natl Acad Sci U S A 106: 21264-21269
Shibuya M (2015) VEGF-VEGFR System as a Target for Suppressing
53
Inflammation and other Diseases. Endocr Metab Immune Disord Drug Targets 15:
135-144
Shinagawa M, Namba K, Mizuuchi K, Iwata D, Hase K, Suzuki K, Hirooka K,
Kitaichi N, Hiraoka M, Ishida S (2022) The Steroid-Sparing Effect of
Adalimumab in the Treatment for the Recurrent Phase of Vogt-Koyanagi-Harada
Disease. Ocul Immunol Inflamm: 1-5
Sillen M, Declerck PJ (2021) A Narrative Review on Plasminogen Activator
Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target? Int J
Mol Sci 22
Sonoda KH, Hasegawa E, Namba K, Okada AA, Ohguro N, Goto H, Group
JJOISUSW (2021) Epidemiology of uveitis in Japan: a 2016 retrospective
nationwide survey. Jpn J Ophthalmol 65: 184-190
Sundberg C, Kowanetz M, Brown LF, Detmar M, Dvorak HF (2002) Stable
expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic
similarities to a subpopulation of cells in maturing vessels during later stages of
angiogenesis in vivo. Lab Invest 82: 387-401
Suzuki K, Ishihara M, Namba K, Ohno S, Goto H, Takase H, Kawano S, Shibuya
E, Hase K, Iwata D et al (2022) Clinical features of ocular sarcoidosis: severe,
refractory, and prolonged inflammation. Jpn J Ophthalmol
Takakura N, Watanabe T, Suenobu S, Yamada Y, Noda T, Ito Y, Satake M, Suda T
(2000) A role for hematopoietic stem cells in promoting angiogenesis. Cell 102:
199-209
Takeuchi M, Kezuka T, Sugita S, Keino H, Namba K, Kaburaki T, Maruyama K,
Nakai K, Hijioka K, Shibuya E et al (2014) Evaluation of the long-term efficacy
and safety of infliximab treatment for uveitis in Behçet's disease: a multicenter
study. Ophthalmology 121: 1877-1884
Thurau SR, Chan CC, Nussenblatt RB, Caspi RR (1997) Oral tolerance in a
murine model of relapsing experimental autoimmune uveoretinitis (EAU):
induction of protective tolerance in primed animals. Clin Exp Immunol 109: 370376
Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K (1980)
Establishment and characterization of a human acute monocytic leukemia cell line
(THP-1). Int J Cancer 26: 171-176
Uemura A, Fruttiger M, D'Amore PA, De Falco S, Joussen AM, Sennlaub F,
Brunck LR, Johnson KT, Lambrou GN, Rittenhouse KD et al (2021) VEGFR1
54
signaling in retinal angiogenesis and microinflammation. Prog Retin Eye Res 84:
100954
Wacker WB, Lipton MM (1965) Experimental allergic uveitis: homologous retina
as uveitogenic antigen. Nature 206: 253-254
Watanabe D, Suzuma K, Suzuma I, Ohashi H, Ojima T, Kurimoto M, Murakami T,
Kimura T, Takagi H (2005) Vitreous levels of angiopoietin 2 and vascular
endothelial growth factor in patients with proliferative diabetic retinopathy. Am J
Ophthalmol 139: 476-481
Weiss K, Steinbrugger I, Weger M, Ardjomand N, Maier R, Wegscheider BJ,
Wedrich A, El-Shabrawi Y (2009) Intravitreal VEGF levels in uveitis patients and
treatment of uveitic macular oedema with intravitreal bevacizumab. Eye (Lond)
23: 1812-1818
Westra J, de Groot L, Plaxton SL, Brouwer E, Posthumus MD, Kallenberg CG,
Bijl M (2011) Angiopoietin-2 is highly correlated with inflammation and disease
activity in recent-onset rheumatoid arthritis and could be predictive for
cardiovascular disease. Rheumatology (Oxford) 50: 665-673
Yamamoto K, Takeshita K, Shimokawa T, Yi H, Isobe K, Loskutoff DJ, Saito H
(2002) Plasminogen activator inhibitor-1 is a major stress-regulated gene:
implications for stress-induced thrombosis in aged individuals. Proc Natl Acad Sci
U S A 99: 890-895
Yano A, Schwartz RH, Paul WE (1977) Antigen presentation in the murine Tlymphocyte proliferative response. I. Requirement for genetic identity at the major
histocompatibility complex. J Exp Med 146: 828-843
Yousef AA, Mohamed FY, Boraey NF, Akeel NE, Soliman AA, Waked NM,
Hashem MIA, Shehata H, Fahmy DS, Ismael A et al (2020) Association of
Plasminogen Activator Inhibitor 1 (PAI-1) 4G/5G Polymorphism and
Susceptibility to SLE in Egyptian Children and Adolescents: A Multicenter Study.
J Inflamm Res 13: 1103-1111
Zhang L, Yang N, Park JW, Katsaros D, Fracchioli S, Cao G, O'Brien-Jenkins A,
Randall TC, Rubin SC, Coukos G (2003) Tumor-derived vascular endothelial
growth factor up-regulates angiopoietin-2 in host endothelium and destabilizes
host vasculature, supporting angiogenesis in ovarian cancer. Cancer Res 63: 34033412
大野 重昭, 岡田 アナベルあやめ, 後藤 浩, 南場 研一, 北市 伸義, 有賀
俊英, 石原 麻美, 臼井 嘉彦, 大黒 伸行, 蕪城 俊克, 慶野 博, 杉田 直,
55
鈴木 潤, 園田 康平, 堤 雅幸, 中尾 久美子, 堀江 幸弘, 水木 信久, 八
代 成子, 横井 克俊, 日本眼炎症学会ぶどう膜炎診療ガイドライン作成
委員会. (2019) ぶどう膜炎診療ガイドライン. 日本眼科学会雑誌 123 巻 6
号 635-696
56
...