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Table S1. The primary questionnaire and the secondary questionnaire
Primary questionnaire
Questions
Responses
1. Sex
Male, Female
2. Age
__ years
3. What area do you live in?
Hokkaido, Tohoku, Kanto, Chubu, Kinki,
Chugoku, Shikoku, Kyushu
4. Equivalent household income (million Japanese
-1.9, 2.0-3.9, 4.0-7.9, 8.0-11.9, 12.0-, Do
Yen)
not know, Unwilling to answer
5. Do you currently smoke?
Do not smoke, Only cigarettes, Only HTPs,
HTPs and cigarettes
6. Which of the following diseases are you currently
Hypertension,
suffering from?
Hyperuricemia/gout,
*Must be diagnosed by a medical institution.
disease, Hepatic disease, Kidney disease,
*Multiple answers possible
Rheumatoid arthritis, Chronic obstructive
pulmonary
Diabetes,
disease,
Dyslipidemia,
Cardiovascular
Cancer,
Atopic
dermatitis, Psoriasis, Others, No disease
Secondary questionnaire
Questions
1.
How often do you drink?
Responses
None, ≤ 1 per month, 2-4 per month, 2~3
per week, ≥ 4 times a week
2.
How many cigarettes do you smoke on average
-10, 11-20, 21-30, 31-
per day?
*Please answer the combined number of cigarettes
and HTPs.
3.
Please tell us your academic history.
Junior high school, High school, University
or Technical school, Graduate school,
Other, Unwilling to answer
4.
Who are your family living together?
Living alone, Parents, Brothers and sisters,
Parents, brothers and sisters, Spouse,
Children, Spouse and children, Parents and
spouse, Parents, spouse and children,
Other
5.
How long you have been diagnosed with
-4.9, 5-9.9, 10-19.9, 20-, Do not know
rheumatoid arthritis?
6.
Which of the following conditions best
Mild, Moderate, Severe, Most severe
describes to your current disease status of
rheumatoid arthritis?
*Class 1 to 4 in the following definition correspond
to mild, moderate, severe, and most severe in this
order.
I - Complete ability to carry out all the usual duties
without handicaps
II - Adequate for normal activities despite handicap
of discomfort or limited motion of one of the joints
III - Limited to little or none of the duties of usual
occupation or self-care
IV - Incapacitated, largely or wholly bed-ridden or
confined to a wheelchair with little or no self-care
https://www.mhlw.go.jp/newinfo/kobetu/kenkou/ryumachi/dl/jouhou01-110003.pdf
7.
Have you ever been hospitalized due to
Yes, No
rheumatoid arthritis?
8.
How did you get started with HTPs?
Switch from cigarettes or add to cigarettes,
From the beginning
9.
Please select one option that best describes the
Less harmful to the health, Less smoke and
reason for HTPs use.
odor, Taste, Appearance/Fashion, More
smoking area, Other
10. Do you think cigarettes and HTPs differ in their
negative impact on your rheumatoid arthritis?
11. Have you ever considered using HTPs due to
Yes - Cigarettes are more harmful, Yes HTPs are more harmful, No
Yes, No
your rheumatoid arthritis?
12. Do you feel that the use of HTPs relieves your
Yes, No
disease? (If you are not using HTPs, answer
based on what you think might occur)
13. After starting HTPs, did your smoking
frequency change? / Do you think smoking
frequency will change once you start using
HTP?
Yes - Increased, Yes - Decreased, No / Yes
- Will increase, Yes - Will decrease, No
...