Barnett T, Liebl D, Seymour L, Gillen C, Lim J, Larock C, Davies M, Schulz B, Nizet V, Teasdale, R, et al (2013) The globally disseminated M1T1 clone of Group A Streptococcus evades autophagy for intracellular replication. Cell Host Microbe 14: 675 – 682
Boyle KB, Randow F (2013) The role of “eat-me” signals and autophagy cargo receptors in innate immunity. Curr Opin Microbiol 16: 339 – 348
Campoy E Colombo M (2006) Autophagy in intracellular bacterial infection. Biochimica et Biophysica Acta 1793: 1465 – 1477
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, Zhong Y, Li B, Wang J, Zhang, L, et al (2019) A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun 10: 1973
Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd M, Kimura T, Choi S, Peters R, Mandell M, Bruun J-A et al (2016) TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis. Dev Cell 39: 13 – 27
Cole JN, Barnett TC, Nizet V, Walker MJ (2011) Molecular insight into invasive group A streptococcal disease. Nat Rev Microbiol 9: 724 – 736 Franco LH, Nair VR, Scharn CR, Xavier RJ, Torrealba JR, Shiloh MU, Levine B (2017) The ubiquitin ligase Smurf1 functions in selective autophagy of Mycobacterium tuberculosis and anti-tuberculous host defense. Cell Host Microbe 21: 59 – 72
Fujita N, Morita E, Itoh T, Tanaka A, Nakaoka M, Osada Y, Umemoto T, Saitoh T, Nakatogawa H, Kobayashi, S, et al (2013) Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin. J Cell Biol 203: 115 – 128
Glenn KA, Nelson RF, Wen HM, Mallinger AJ, Paulson HL (2008) Diversity in tissue expression, substrate binding, and SCF complex formation for a lectin family of ubiquitin ligases. J Biol Chem 283: 12717 – 12729
Henningham A, Davies MR, Uchiyama S, van Sorge NM, Lund S, Chen KT, Walker MJ, Cole JN, Nizet V (2018) Virulence role of the GlcNAc side chain of the lancefield cell wall carbohydrate antigen in non-M1-serotype group A Streptococcus. MBio 9: e02294-17
Huett A, Heath RJ, Begun J, Sassi SO, Baxt LA, Vyas JM, Goldberg MB, Xavier RJ (2012) The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium. Cell Host Microbe 12: 778 – 790
Ito C, Saito Y, Nozawa T, Fujii S, Sawa T, Inoue H, Matsunaga T, Khan S, Akashi S, Hashimoto R et al (2013) Endogenous nitrated nucleotide is a key mediator of autophagy and innate defense against bacteria. Mol Cell 52: 794 – 804
Levine B, Deretic V (2007) Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 7: 767 – 777
Lin CY, Nozawa T, Minowa-Nozawa A, Toh H, Aikawa C, Nakagawa I (2019) LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy. Cell Microbiol 21: e12981
Liu EA, Schultz ML, Mochida C, Chung C, Paulson HL, Lieberman AP (2020) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain. JCI Insight 5: e136676
Lu SL, Kawabata T, Cheng YL, Omori H, Hamasaki M, Kusaba T, Iwamoto R, Arimoto H, Noda T, Lin YS et al (2017) Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes. PLoS Pathog 13: e1006444
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS (2013) The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature 501: 512 – 516
McCarty M (1952) The lysis of group A hemolytic streptococci by extracellular enzymes of Streptomyces albus. II. Nature of the cellular substrate attacked by the lytic enzymes. J Exp Med 96: 569 – 580
Minowa-Nozawa A, Nozawa T, Okamoto-Furuta K, Kohda H, Nakagawa I (2017) Rab35 GTPase recruits NDP52 to autophagy targets. EMBO J 36: 2790 – 2807
Mizushima T, Hirao T, Yoshida Y, Lee SJ, Chiba T, Iwai K, Yamaguchi Y, Kato K, Tsukihara T, Tanaka K (2004) Structural basis of sugar-recognizing ubiquitin ligase. Nat Struct Mol Biol 11: 365 – 370
Nakagawa I, Amano A, Mizushima N, Yamamoto A, Yamaguchi H, Kamimoto T, Nara A, Funao J, Nakata M, Tsuda, K, et al (2004) Autophagy defends cells against invading group A Streptococcus. Science 306: 1037 – 1040
Nagata Y, Burger MM (1974) Wheat germ agglutinin. Molecular characteristics and specificity for sugar binding. J Biol Chem 249: 3116 – 3122
Noad J, von der Malsburg A, Pathe C, Michel MA, Komander D, Randow F (2017) LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-jB. Nat Microbiol 2: 17063
Nozawa T, Sano S, Minowa-Nozawa A, Toh H, Nakajima S, Murase K, Aikawa C, Nakagawa I (2020) TBC1D9 regulates TBK1 activation through Ca(2+) signaling in selective autophagy. Nat Commun 11: 770
Ogawa M, Matsuda R, Takada N, Tomokiyo M, Yamamoto S, Shizukusihi S, Yamaji T, Yoshikawa Y, Yoshida M, Tanida I et al (2018) Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination. Cell Microbiol 20: e12846
O’Seaghdha M, Wessels M (2019) Streptolysin O and its co-toxin NADglycohydrolase protect group A Streptococcus from Xenophagic killing. PLos Pathog 9: e1003394 Otten EG, Werner E, Crespillo-Casado A, Boyle KB, Dharamdasani V, Pathe C, Santhanam B, Randow F (2021) Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection. Nature 594: 111 – 116
Paz I, Sachse M, Dupont N, Mounier J, Cederfur C, Enninga J, Leffler H, Poirier F, Prevost M-C, Lafont F et al (2010) Galectin-3, a marker for vacuole lysis by invasive pathogens. Cell Microbiol 12: 530 – 544
Rush JS, Edgar RJ, Deng P, Chen J, Zhu H, van Sorge NM, Morris AJ, Korotkov KV, Korotkova N (2017) The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes. J Biol Chem 292: 19441 – 19457
Thurston TL, Wandel MP, von Muhlinen N, Foeglein A, Randow F (2012) Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion. Nature 482: 414 – 418
Toh H, Nozawa T, Minowa-Nozawa A, Hikichi M, Nakajima S, Aikawa C, Nakagawa I (2020) Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy. Autophagy 16: 334 – 346
van Sorge N, Cole J, Kuipers K, Henningham A, Aziz R, Kasirer-Friede A, Lin L, Berends E, Davies M, Dougan G et al (2014) The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host Microbe 15: 729 – 740
Xu Y, Zhou P, Cheng S, Lu Q, Nowak K, Hopp A-K, Li L, Shi X, Zhou Z, Gao W et al (2019) A bacterial effector reveals the V-ATPase-ATG16L1 axis that initiates Xenophagy. Cell 178: 552 – 566.e20
Yang Y, Kitagaki J, Dai R-M, Tsai YC, Lorick KL, Ludwig RL, Pierre SA, Jensen JP, Davydov IV, Oberoi P et al (2007) Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. Can Res 67: 9472 – 9481
Yoshida Y, Chiba T, Tokunaga F, Kawasaki H, Iwai K, Suzuki T, Ito Y, Matsuoka K, Yoshida M, Tanaka K et al (2002) E3 ubiquitin ligase that recognizes sugar chains. Nature 418: 438 – 442
Yoshida Y, Yasuda S, Fujita T, Hamasaki M, Murakami A, Kawawaki J, Iwai K, Saeki Y, Yoshimori T, Matsuda N et al (2017) Ubiquitination of exposed glycoproteins by SCF(FBXO27) directs damaged lysosomes for autophagy. Proc Natl Acad Sci USA 114: 8574 – 8579
Zhou X, Zhao G, Truglio JJ, Wang L, Li G, Lennarz WJ, Schindelin H (2006) Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module. Proc Natl Acad Sci USA 103: 17214 – 17219