Agostinelli, S., Allison, J., Amako, K., Apostolakis, J., Araujo, H., Arce, P., Asai, M., Axen, D., Banerjee, S., Barrand, G., et al., 2003. Geant4—a simulation toolkit. Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip. 506, 250–303.
Akagi, T., Aso, T., Faddegon, B., Kimura, A., Matsufuji, N., Nishio, T., Omachi, C., Paganetti, H., Perl, J., Sasaki, T., et al., 2011. The PTSim and TOPAS Projects, Bringing Geant4 to the Particle Therapy Clinic. Prog. Nucl. Sci. Technol. 2, 912–917.
Allison, J., Amako, K., Apostolakis, J., Araujo, H., Arce Dubois, P., Asai, M., Barrand, G., Capra, R., Chauvie, S., Chytracek, R., et al., 2006. Geant4 developments and applications. IEEE Trans. Nucl. Sci. 53, 270–278.
Allison, J., Amako, K., Apostolakis, J., Arce, P., Asai, M., Aso, T., Bagli, E., Bagulya, A., Banerjee, S., Barrand, G., et al., 2016. Recent developments in Geant4. Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip. 835, 186–225.
Alper, T., 1956. The Modification of Damage Caused by Primary Ionization of Biological Targets. Radiat. Res. 5, 573.
Anderson, A.R., Hart, E.J., 1961. Molecular Product and Free Radical Yields in the Decomposition of Water by Protons , Deuterons , and Helium Ions1 704, 689–704.
Ando, K., Koike, S., Ohira, C., Chen, Y.J., Nojima, K., Ando, S., Ohbuchi, T., Kobayashi, N., Shimizu, W., Urano, M., 1999. Accelerated reoxygenation of a murine fibrosarcoma after carbon-ion radiation. Int. J. Radiat. Biol. 75, 505–512.
Appleby, A., Schwarz, H.A., 1969. Radical and molecular yields in water irradiated by .gamma.-rays and heavy ions. J. Phys. Chem. 73, 1937–1941.
Baba, K., Kusumoto, T., Okada, S., Ishikawa, M., 2021a. A simulation-based study on water radiolysis species for 1H+4He2+, and 12C6+ ion beams with multiple ionization using Geant4-DNA. J. Appl. Phys. 129.
Baba, K., Kusumoto, T., Okada, S., Ogawara, R., Kodaira, S., Raffy, Q., Barillon, R., Ludwig, N., Galindo, C., Peaupardin, P., et al., 2021b. Quantitative estimation of track segment yields of water radiolysis species under heavy ions around Bragg peak energies using Geant4-DNA. Sci. Rep. 11, 1– 11.
Baldacchino, G, Bouffard, S., Balanzat, E., Gardès-Albert, M., Abedinzadeh, Z., Jore, D., Deycard, S., Hickel, B., 1998. Direct time-resolved measurement of radical species formed in water by heavy ions irradiation. Nucl. Instruments Methods Phys. Res. Sect. B Beam Interact. with Mater. Atoms 146, 528–532.
Baldacchino, G., Le Parc, D., Hickel, B., Gardes-Albert, M., Abedinzadeh, Z., Jore, D., Deycard, S., Bouffard, S., Mouton, V., Balanzat, E., 1998. Direct observation of HO2/O2- free radicals generated in water by a high-linear energy transfer pulsed heavy-ion beam. Radiat. Res. 149, 128–133.
Bartels, D.M., Andrew R. Cook, Mohan Mudaliar, A., Jonah, C.D., 2000. Spur Decay of the Solvated Electron in Picosecond Radiolysis Measured with Time-Correlated Absorption Spectroscopy.
Bernal, M.A., Bordage, M.C., Brown, J.M.C., Davídková, M., Delage, E., El Bitar, Z., Enger, S.A., Francis, Z., Guatelli, S., Ivanchenko, V.N., et al., 2015. Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit. Phys. Medica 31, 861–874.
Bordage, M.C., Bordes, J., Edel, S., Terrissol, M., Franceries, X., Bardiès, M., Lampe, N., Incerti, S., 2016. Implementation of new physics models for low energy electrons in liquid water in Geant4- DNA. Phys. Medica 32, 1833–1840.
Bordes, J., Incerti, S., Lampe, N., Bardiès, M., Bordage, M.-C., 2017. Low-energy electron dose- point kernel simulations using new physics models implemented in Geant4-DNA. Nucl. Instruments Methods Phys. Res. Sect. B Beam Interact. with Mater. Atoms 398, 13–20.
Boscolo, D., Krämer, M., Fuss, M.C., Durante, M., Scifoni, E., 2020. Impact of target oxygenation on the chemical track evolution of ion and electron radiation. Int. J. Mol. Sci. 21.
Burns, W.G., Sims, H.E., 1981. Effect of radiation type in water radiolysis. J. Chem. Soc. Faraday Trans. 1 Phys. Chem. Condens. Phases 77, 2803–2813.
Buxton, G. V., Greenstock, C.L., Helman, W.P., Ross, A.B., 1988. Critical Review of rate constants for reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals (⋅OH/⋅O − in Aqueous Solution. J. Phys. Chem. Ref. Data 17, 513–886.
Champion, C., 2003. Multiple ionization of water by heavy ions: A Monte Carlo approach. Nucl. Instruments Methods Phys. Res. Sect. B Beam Interact. with Mater. Atoms 205, 671–676.
Champion, C., Incerti, S., Aouchiche, H., Oubaziz, D., 2009. A free-parameter theoretical model for describing the electron elastic scattering in water in the Geant4 toolkit. Radiat. Phys. Chem. 78, 745– 750.
Cobut, V., Frongillo, Y., Patau, J.P., Goulet, T., Fraser, M.-J., Jay-Gerin, J.-P., 1998. Monte Carlo simulation of fast electron and proton tracks in liquid water - I. Physical and physicochemical aspects. Radiat. Phys. Chem. 51, 229–243.
Frongillo, Y., Goulet, T., Fraser, M.J., Cobut, V., Patau, J.P., Jay-Gerin, J.P., 1998. Monte carlo simulation of fast electron and proton tracks in liquid water - II. Nonhomogeneous chemistry. Radiat. Phys. Chem. 51, 245–254.
Furusawa, Y., Fukutsu, K., Aoki, M., Itsukaichi, H., Eguchi-Kasai, K., Ohara, H., Yatagai, F., Kanai, T., Ando, K., 2000. Inactivation of aerobic and hypoxic cells from three different cell lines by accelerated (3)He-, (12)C- and (20)Ne-ion beams. Radiat. Res. 154.
Gervais, B., Beuve, M., Olivera, G.H., Galassi, M.E., 2006. Numerical simulation of multiple ionization and high LET effects in liquid water radiolysis. Radiat. Phys. Chem. 75, 493–513.
Hatano, Y., Katsumura, Y., Mozumder, A., 2011. Charged particle and photon interactions with matter : recent advances, applications, and interfaces. CRC Press.
Henglein, A., 1991. J. W. T. Spinks. R. J. Woods: An Introduction to Radiation Chemistry, Third Edition, John-Wiley and Sons, Inc., New York, Toronto 1990. ISBN 0-471-61403-3. 574 Seiten, Preis: DM 91, 45. Berichte der Bunsengesellschaft für Phys. Chemie 95, 451–451.
Hirano, Y., Kodaira, S., Souda, H., Matsumura, A., Torikoshi, M., 2018. Linear energy transfer (LET) spectra and survival fraction distribution based on the CR-39 plastic charged-particle detector in a spread-out Bragg peak irradiation by a 12C beam. Phys. Med. Biol. 63.
Hirayama, R., Ito, A., Tomita, M., Tsukada, T., Yatagai, F., Noguchi, M., Matsumoto, Y., Kase, Y., Ando, K., Okayasu, R., et al., 2009. Contributions of Direct and Indirect Actions in Cell Killing by High-LET Radiations. Radiat. Res. 171, 212–218.
Hirayama, R., Uzawa, A., Takase, N., Matsumoto, Y., Noguchi, M., Koda, K., Ozaki, M., Yamashita, K., Li, H., Kase, Y., et al., 2013. Evaluation of SCCVII tumor cell survival in clamped and non- clamped solid tumors exposed to carbon-ion beams in comparison to X-rays. Mutat. Res. - Genet. Toxicol. Environ. Mutagen. 756, 146–151.
Incerti, S., Baldacchino, G., Bernal, M., Capra, R., Champion, C., Francis, Z., GuÈye, P., Mantero, A., Mascialino, B., Moretto, P., et al., 2010a. THE Geant4-DNA project. Int. J. Model. Simulation, Sci. Comput. 1, 157–178.
Incerti, S., Ivanchenko, A., Karamitros, M., Mantero, A., Moretto, P., Tran, H.N., Mascialino, B., Champion, C., Ivanchenko, V.N., Bernal, M.A., et al., 2010b. Comparison of GEANT4 very low energy cross section models with experimental data in water. Med. Phys. 37, 4692–4708.
Incerti, S., Kyriakou, I., Bernal, M.A., Bordage, M.C., Francis, Z., Guatelli, S., Ivanchenko, V., Karamitros, M., Lampe, N., Lee, S.B., et al., 2018. Geant4-DNA example applications for track structure simulations in liquid water: A report from the Geant4-DNA Project. Med. Phys. 45, e722– e739.
Jay-Gerin, J.-P., Ferradini, C., Jay-Gerin, J.-P., Ferradini, C., 2000. A new estimate of the radical yield at early times in the radiolysis of liquid water. Chem. Phys. Lett. 317, 388–391.
Karamitros, M., Luan, S., Bernal, M.A., Allison, J., Baldacchino, G., Davidkova, M., Francis, Z., Friedland, W., Ivantchenko, V., Ivantchenko, A., et al., 2014. Diffusion-controlled reactions modeling in Geant4-DNA. J. Comput. Phys. 274, 841–882.
Karamitros, M., Mantero, A., Incerti, S., Friedland, W., Baldacchino, G., Barberet, P., Bernal, M., Capra, R., Champion, C., El Bitar, Z., et al., 2011. Modeling Radiation Chemistry in the Geant4 Toolkit, Progress in Nuclear Science and Technology.
Kusumoto, T., Kitamura, H., Hojo, S., Konishi, T., Kodaira, S., 2020. Significant changes in yields of 7-hydroxy-coumarin-3-carboxylic acid produced under FLASH radiotherapy conditions. RSC Adv. 10, 38709–38714.
Kusumoto, T., Mori, Y., Kanasaki, M., Ikenaga, R., Oda, K., Kodaira, S., Kitamura, H., Barillon, R., Yamauchi, T., 2016. Radiation chemical yields for the losses of typical functional groups in PADC films for high energy protons registered as unetchable tracks. Radiat. Meas. 87, 35–42.
Kyriakou, I., Incerti, S., Francis, Z., 2015. Technical Note: Improvements in geant 4 energy-loss model and the effect on low-energy electron transport in liquid water. Med. Phys. 42, 3870–3876.
Kyriakou, I., Šefl, M., Nourry, V., Incerti, S., 2016. The impact of new Geant4-DNA cross section models on electron track structure simulations in liquid water. J. Appl. Phys. 119, 194902.
Lai, Y., Jia, X., Chi, Y., 2021. Modeling the effect of oxygen on the chemical stage of water radiolysis using GPU-based microscopic Monte Carlo simulations, with an application in FLASH radiotherapy. Phys. Med. Biol. 66, 025004.
LaVerne, J.A., 2000. OH Radicals and Oxidizing Products in the Gamma Radiolysis of Water. Radiat. Res.
LaVerne, J.A., Moriarty, M., Mothersill, C., Seymour, C., Edington, M., Ward, J.F., Fry, R.J.M., Eds., 2000. In. Radiat. Res. Proc. 11th Int. Congr. Radiat. Res. Dublin, Ireland, July 18- 23, 1999, Vol. 2; Allen Press Lawrence, KS,.
LaVerne, J.A., Pimblott, S.M., 1991. Scavenger and time dependences of radicals and molecular products in the electron radiolysis of water: examination of experiments and models. J. Phys. Chem. 95, 3196–3206.
Laverne, J.A., Yoshida, H., 1993. Production of the Hydrated Electron in the Radiolysis of Water with Helium Ions, J. Phys. Chem.
Ludwig, N., 2018. Modification d ’ acides aminés et de faisceau d ’ ions.
Ludwig, N., Kusumoto, T., Galindo, C., Peaupardin, P., Pin, S., Renault, J.-P., Muller, D., Yamauchi, T., Kodaira, S., Barillon, R., et al., 2018. Radiolysis of phenylalanine in solution with Bragg-Peak energy protons. Radiat. Meas. 116, 55–59.
Maeyama, T., Yamashita, S., Baldacchino, G., Taguchi, M., Kimura, A., Murakami, T., Katsumura, Y., 2011. Production of a fluorescence probe in ion-beam radiolysis of aqueous coumarin-3- carboxylic acid solution-1: Beam quality and concentration dependences. Radiat. Phys. Chem. 80, 535–539.
Meesungnoen, J., Filali-Mouhim, A., Ayudhya, N.S.N., Mankhetkorn, S., Jay-Gerin, J.-P., 2003. Multiple ionization effects on the yields of HO2/O2− and H2O2 produced in the radiolysis of liquid water with high-LET 12C6+ ions: a Monte-Carlo simulation study. Chem. Phys. Lett. 377, 419–425.
Meesungnoen, J., Jay-Gerin, J.P., 2009. High-let ion radiolysis of water: Oxygen production in tracks. Radiat. Res. 171, 379–386.
Meesungnoen, J., Jay-Gerin, J.P., 2005a. High-LET radiolysis of liquid water with1H+, 4He2+, 12C6+, and 20Ne9+ ions: Effects of multiple ionization. J. Phys. Chem. A 109, 6406–6419.
Meesungnoen, J., Jay-Gerin, J.P., 2005b. Effect of multiple ionization on the yield of H2O2 produced in the radiolysis of aqueous 0.4 M H2SO4 solutions by high-LET 12C6+ and 20Ne 9+ ions. Radiat. Res. 164, 688–694.
Melton, C.E., 2003. Cross Sections and Interpretation of Dissociative Attachment Reactions Producing OH-, O-, and H- in H2O, THE JOURNAL OF CHEMICAL PHYSICS.
Michaud, M., Wen, A., Sanche, L., 2003. Cross Sections for Low-Energy (1–100 eV) Electron Elastic and Inelastic Scattering in Amorphous Ice. https://doi.org/10.1667/0033- 7587(2003)159[0003:CSFLEE]2.0.CO;2 159, 3–22.
Morawetz, H., 1987. Radiation chemistry-principles and applications, Farhataziz and Michael A. J. Rodgers, Eds. VCH, New York and Germany, 1987, 641 pp. Price: J. Polym. Sci. Part C Polym. Lett. 25, 510–510.
Mott, N.F., Massey, H.S.W., 1965. The theory of Atomic Collisions Clarendon Press, Oxford, 1965), Vol. 35.
Muroya, Y., 2017. 5 Radiation Chemistry of Water and Aqueous Solutions. Radioisotopes 66, 425– 435.
Nikjoo, H., O’Neill, P., Goodhead, D.T., Terrissol, M., 1997. Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events. Int. J. Radiat. Biol. 71, 467– 83.
Pastina, B., LaVerne, J.A., 1999. Hydrogen peroxide production in the radiolysis of water with heavy ions. J. Phys. Chem. A 103, 1592–1597.
Peudon, A., Edel, S., Terrissol, M., 2006. Molecular basic data calculation for radiation transport in chromatin. Radiat. Prot. Dosimetry 122, 128–135.
Peukert, D., Incerti, S., Kempson, I., Douglass, M., Karamitros, M., Baldacchino, G., Bezak, E., 2019. Validation and investigation of reactive species yields of Geant4-DNA chemistry models. Med. Phys. 46, 983–998.
Pimblott, S.M., LaVerne, J.A., 1998. Effect of Electron Energy on the Radiation Chemistry of Liquid Water. Radiat. Res. 150, 159.
Pimblott, S.M., LaVerne, J.A., 1997. Stochastic Simulation of the Electron Radiolysis of Water and Aqueous Solutions.
Plante, I., 2011. A Monte-Carlo step-by-step simulation code of the non-homogeneous chemistry of the radiolysis of water and aqueous solutions. Part I: Theoretical framework and implementation. Radiat. Environ. Biophys. 50, 389–403.
Pratx, G., Kapp, D.S., 2019. A computational model of radiolytic oxygen depletion during FLASH irradiation and its effect on the oxygen enhancement ratio. Phys. Med. Biol. 64.
Rudd, M.E., 1990. Cross Sections for Production of Secondary Electrons by Charged Particles. Radiat. Prot. Dosimetry 31, 17–22.
Scifoni, E., Tinganelli, W., Weyrather, W.K., Durante, M., Maier, A., Krämer, M., 2013. Including oxygen enhancement ratio in ion beam treatment planning: model implementation and experimental verification. Phys. Med. Biol. 58, 3871–3895.
Shin, W.G., Ramos-Mendez, J., Faddegon, B., Tran, H.N., Villagrasa, C., Perrot, Y., Okada, S., Karamitros, M., Emfietzoglou, D., Kyriakou, I., et al., 2019. Evaluation of the influence of physical and chemical parameters on water radiolysis simulations under MeV electron irradiation using Geant4-DNA. J. Appl. Phys. 126.
Sims, H.E., Ashmore, C.B., Tait, P.K., Walters, W.S., 1998. Yields of water radiolysis products from proton irradiated water. 1998 JAIF Int. Conf. water Chem. Nucl. power plants, Proc. p 894.
Sumiyoshi, T., Katayama, M., 1982. THE YIELD OF HYDRATED ELECTRONS AT 30 PICOSECONDS. Chem. Lett. 11, 1887–1890.
Taguchi, M., Kojima, T., 2007. Yield of OH radicals in water under heavy ion irradiation. Dependence on mass, specific energy, and elapsed time. Nucl. Sci. Tech. 18, 35–38.
Tomita, H., Kai, M., Kusama, T., Ito, A., 1997. Monte Carlo simulation of physicochemical processes of liquid water radiolysis. Radiat. Environ. Biophys. 36, 105–116.
Waligórski, M.P.R., Hamm, R.N., Katz, R., 1986. The radial distribution of dose around the path of a heavy ion in liquid water. Int. J. Radiat. Appl. Instrumentation. Part 11, 309–319.
Wasselin-Trupin, V., Baldacchino, G., Bouffard, S., Hickel, B., 2002. Hydrogen peroxide yields in water radiolysis by high-energy ion beams at constant LET. Radiat. Phys. Chem. 65, 53–61.
Yamashita, S., Katsumura, Y., Lin, M., Muroya, Y., Maeyama, T., Murakami, T., 2008. Water radiolysis with heavy ions of energies up to 28 GeV-2: Extension of primary yield measurements to very high LET values. Radiat. Phys. Chem. 77, 1224–1229.