1. Rodríguez-Estival, J.; Mateo, R. Exposure to Anthropogenic Chemicals in Wild Carnivores: A Silent Conservation Threat Demanding Long-Term Surveillance. Curr. Opin. Environ. Sci. Heal. 2019, 11, 21–25, doi:10.1016/j.coesh.2019.06.002.
2. Johnson, A.C.; Jin, X.; Nakada, N.; Sumpter, J.P. Learning from the Past and Considering the Future of Chemicals in the Environment. Science (80-. ). 2020, 367, 384–387, doi:10.1126/SCIENCE.AAY6637/ASSET/4F3E33CB-9FC0-409D-B480- 80B0CB00A941/ASSETS/GRAPHIC/367_384_F4.JPEG.
3. Rattner, B.A. History of Wildlife Toxicology. Ecotoxicology 2009, 18, 773– 783, doi:10.1007/s10646-009-0354-x.
4. Sainsbury, K.A.; Shore, R.F.; Schofield, H.; Croose, E.; Pereira, M.G.; Sleep, D.; Kitchener, A.C.; Hantke, G.; McDonald, R.A. Long-Term Increase in Secondary Exposure to Anticoagulant Rodenticides in European Polecats Mustela Putorius in Great Britain. Environ. Pollut. 2018, 236, 689–698, doi:10.1016/j.envpol.2018.02.004.
5. Chaousis, S.; Leusch, F.D.L.; van de Merwe, J.P. Charting a Path towards Non-Destructive Biomarkers in Threatened Wildlife: A Systematic Quantitative Literature Review. Environ. Pollut. 2018, 234, 59–70, doi:10.1016/j.envpol.2017.11.044.
6. Köhler, H.R.; Triebskorn, R. Wildlife Ecotoxicology of Pesticides: Can We Track Effects to the Population Level and Beyond? Science (80-. ). 2013, 341, 759–765.
7. Carson, R. Silent Spring. In Silent Spring; Houghton Mifflin Company, 1964.
8. Turusov, V.; Rakitsky, V.; Tomatis, L. Dichlorodiphenyltrichloroethane (DDT): Ubiquity, Persistence, and Risks. Environ. Health Perspect. 2002, 110, 125–128, doi:10.1289/ehp.02110125.
9. Ratcliffe, D.A. Changes Attributable to Pesticides in Egg Breakage Frequency and Eggshell Thickness in Some British Birds. J. Appl. Ecol. 1970, 7, 67, doi:10.2307/2401613. 85
10. Bernanke, J.; Köhler, H.R. The Impact of Environmental Chemicals on Wildlife Vertebrates. Rev. Environ. Contam. Toxicol. 2009, 198, 1–47, doi:10.1007/978-0-387-09647-6_1.
11. Vorkamp, K.; Rigét, F.F.; Glasius, M.; Muir, D.C.G.; Dietz, R. Levels and Trends of Persistent Organic Pollutants in Ringed Seals (Phoca Hispida) from Central West Greenland, with Particular Focus on Polybrominated Diphenyl Ethers (PBDEs). Environ. Int. 2008, 34, 499–508, doi:10.1016/j.envint.2007.11.004.
12. Dietz, R.; Gustavson, K.; Sonne, C.; Desforges, J.P.; Rigét, F.F.; Pavlova, V.; McKinney, M.A.; Letcher, R.J. Physiologically-Based Pharmacokinetic Modelling of Immune, Reproductive and Carcinogenic Effects from Contaminant Exposure in Polar Bears (Ursus Maritimus) across the Arctic. Environ. Res. 2015, 140, 45–55, doi:10.1016/j.envres.2015.03.011.
13. Rodríguez-Jorquera, I.A.; Vitale, N.; Garner, L.; Perez-Venegas, D.J.; Galbán-Malagón, C.J.; Duque-Wilckens, N.; Toor, G.S. Contamination of the Upper Class: Occurrence and Effects of Chemical Pollutants in Terrestrial Top Predators. Curr. Pollut. Reports 2017, 3, 206–219, doi:10.1007/s40726-017-0061-9.
14. Routti, H.; Atwood, T.C.; Bechshoft, T.; Boltunov, A.; Ciesielski, T.M.; Desforges, J.P.; Dietz, R.; Gabrielsen, G.W.; Jenssen, B.M.; Letcher, R.J.; et al. State of Knowledge on Current Exposure, Fate and Potential Health Effects of Contaminants in Polar Bears from the Circumpolar Arctic. Sci. Total Environ. 2019, 664, 1063–1083, doi:10.1016/j.scitotenv.2019.02.030.
15. Desforges, J.P.; Hall, A.; McConnell, B.; Rosing-Asvid, A.; Barber, J.L.; Brownlow, A.; De Guise, S.; Eulaers, I.; Jepson, P.D.; Letcher, R.J.; et al. Predicting Global Killer Whale Population Collapse from PCB Pollution. Science (80-. ). 2018, 361, 1373–1376, doi:10.1126/SCIENCE.AAT1953.
16. Sonne, C.; Siebert, U.; Gonnsen, K.; Desforges, J.P.; Eulaers, I.; Persson, S.; Roos, A.; Bäcklin, B.M.; Kauhala, K.; Tange Olsen, M.; et al. Health Effects from Contaminant Exposure in Baltic Sea Birds and Marine Mammals: A Review. Environ. Int. 2020, 139, 105725, doi:10.1016/j.envint.2020.105725.
17. Bradley, M.M.; Perra, M.; Ahlstrøm, Ø.; Jenssen, B.M.; Jørgensen, E.H.; Fuglei, E.; Muir, D.C.G.; Sonne, C. Mandibular Shape in Farmed Arctic 86 Foxes (Vulpes Lagopus) Exposed to Persistent Organic Pollutants. Sci. Total Environ. 2019, 646, 1063–1068, doi:10.1016/j.scitotenv.2018.07.367.
18. Huang, A.C.; Nelson, C.; Elliott, J.E.; Guertin, D.A.; Ritland, C.; Drouillard, K.; Cheng, K.M.; Schwantje, H.M. River Otters (Lontra Canadensis) “Trapped” in a Coastal Environment Contaminated with Persistent Organic Pollutants: Demographic and Physiological Consequences. Environ. Pollut. 2018, 238, 306–316, doi:10.1016/j.envpol.2018.03.035.
19. Casida, J.E.; Quistad, G.B. Golden Age of Insecticide Research: Past, Present, or Future? Annu. Rev. Entomol. 1998, 43, 1–16, doi:10.1146/ANNUREV.ENTO.43.1.1.
20. Grilo, A.; Moreira, A.; Carrapiço, B.; Belas, A.; Braz, B.S. Epidemiological Study of Pesticide Poisoning in Domestic Animals and Wildlife in Portugal: 2014-2020. Front. Vet. Sci. 2021, 7, 1181, doi:10.3389/FVETS.2020.616293/XML/NLM.
21. Casida, J.E.; Durkin, K.A. Neuroactive Insecticides: Targets, Selectivity, Resistance, and Secondary Effects. Annu. Rev. Entomol. 2013, 58, 99– 117, doi:10.1146/annurev-ento-120811-153645.
22. Costa, C.; Silvari, V.; Melchini, A.; Catania, S.; Heffron, J.J.; Trovato, A.; De Pasquale, R. Genotoxicity of Imidacloprid in Relation to Metabolic Activation and Composition of the Commercial Product. Mutat. Res. - Genet. Toxicol. Environ. Mutagen. 2009, 672, 40–44, doi:10.1016/j.mrgentox.2008.09.018.
23. Roy, C.L.; Coy, P.L. Wildlife Consumption of Neonicotinoid-Treated Seeds at Simulated Seed Spills. Environ. Res. 2020, 190, 109830, doi:10.1016/J.ENVRES.2020.109830.
24. Gibbons, D.; Morrissey, C.; Mineau, P. A Review of the Direct and Indirect Effects of Neonicotinoids and Fipronil on Vertebrate Wildlife. Environ. Sci. Pollut. Res. 2015, 22, 103–118, doi:10.1007/s11356-014-3180-5.
25. Takaku, T.; Mikata, K.; Matsui, M.; Nishioka, K.; Isobe, N.; Kaneko, H. In Vitro Metabolism of Trans-Permethrin and Its Major Metabolites, PBalc and PBacid, in Humans. J. Agric. Food Chem. 2011, 59, 5001–5005, doi:10.1021/jf200032q.
26. Riley, S.P.D.; Serieys, L.E.K.; Moriarty, J.G. Infectious Disease and Contaminants in Urban Wildlife: Unseen and Often Overlooked Threats. 87 Urban Wildl. Conserv. Theory Pract. 2014, 175–215, doi:10.1007/978-1- 4899-7500-3_10/COVER.
27. Gabriel, M.W.; Woods, L.W.; Wengert, G.M.; Stephenson, N.; Higley, J.M.; Thompson, C.; Matthews, S.M.; Sweitzer, R.A.; Purcell, K.; Barrett, R.H.; et al. Patterns of Natural and Human-Caused Mortality Factors of a Rare Forest Carnivore, the Fisher (Pekania Pennanti) in California. PLoS One 2015, 10, doi:10.1371/journal.pone.0140640.
28. Rattner, B.A.; Mastrota, F.N. Anticoagulant Rodenticide Toxicity to NonTarget Wildlife Under Controlled Exposure Conditions. In Anticoagulant Rodenticides and Wildlife. Emerging Topics in Ecotoxicology, vol 5.; 2018; pp. 45–86.
29. Serieys, L.E.K.; Armenta, T.C.; Moriarty, J.G.; Boydston, E.E.; Lyren, L.M.; Poppenga, R.H.; Crooks, K.R.; Wayne, R.K.; Riley, S.P.D. Anticoagulant Rodenticides in Urban Bobcats: Exposure, Risk Factors and Potential Effects Based on a 16-Year Study. Ecotoxicology 2015, 24, 844–862, doi:10.1007/s10646-015-1429-5.
30. Klaassen, C.D. Casarett & Doull’s Toxicology: The Basic Science of Poisons, 9th Edition; 2013; ISBN 9780071769228.
31. Li, Y.; Meng, Q.; Yang, M.; Liu, D.; Hou, X.; Tang, L.; Wang, X.; Lyu, Y.; Chen, X.; Liu, K.; et al. Current Trends in Drug Metabolism and Pharmacokinetics. Acta Pharm. Sin. B 2019, 9, 1113–1144, doi:10.1016/j.apsb.2019.10.001.
32. Esteves, F.; Rueff, J.; Kranendonk, M. The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family. J. Xenobiotics 2021, 11, 94–114, doi:10.3390/jox11030007.
33. Verma, H.; Singh Bahia, M.; Choudhary, S.; Kumar Singh, P.; Silakari, O. Drug Metabolizing Enzymes-Associated Chemo Resistance and Strategies to Overcome It. Drug Metab. Rev. 2019, 51, 196–223, doi:10.1080/03602532.2019.1632886.
34. Trepanier, L.A.; Ray, K.; Winand, N.J.; Spielberg, S.P.; Cribb, A.E. Cytosolic Arylamine N-Acetyltransferase (NAT) Deficiency in the Dog and Other Canids Due to an Absence of NAT Genes. Biochem. Pharmacol. 1997, 54, 73–80, doi:10.1016/S0006-2952(97)00140-8.
35. Ingelman-Sundberg, M.; Sim, S.C.; Gomez, A.; Rodriguez-Antona, C. Influence of Cytochrome P450 Polymorphisms on Drug Therapies: 88 Pharmacogenetic, Pharmacoepigenetic and Clinical Aspects. Pharmacol. Ther. 2007, 116, 496–526, doi:10.1016/J.PHARMTHERA.2007.09.004.
36. Stingl, J.C.; Bartels, H.; Viviani, R.; Lehmann, M.L.; Brockmöller, J. Relevance of UDP-Glucuronosyltransferase Polymorphisms for Drug Dosing: A Quantitative Systematic Review. Pharmacol. Ther. 2014, 141, 92–116, doi:10.1016/j.pharmthera.2013.09.002.
37. Hildebrandt, M.; Carrington, D.P.; Thomae, B.A.; Eckloff, B.W.; Schaid, D.J.; Yee, V.C.; Weinshilboum, R.M.; Wieben, E.D. Genetic Diversity and Function in the Human Cytosolic Sulfotransferases. Pharmacogenomics J. 2007, 7, 133–143, doi:10.1038/sj.tpj.6500404.
38. Trepanier, L.A. Idiosyncratic Toxicity Associated with Potentiated Sulfonamides in the Dog. J. Vet. Pharmacol. Ther. 2004, 27, 129–138, doi:10.1111/J.1365-2885.2004.00576.X.
39. Court, M.H.; Greenblatt, D.J. Molecular Genetic Basis for Deficient Acetaminophen Glucuronidation by Cats: UGT1A6 Is a Pseudogene, and Evidence for Reduced Diversity of Expressed Hepatic UGT1A Isoforms. Pharmacogenetics 2000, 10, 355–369, doi:Doi 10.1097/00008571- 200006000-00009.
40. Court, M.H.; Greenblatt, D.J. Biochemical Basis for Deficient Paracetamol Glucuronidation in Cats: An Interspecies Comparison of Enzyme Constraint in Liver Microsomes. J. Pharm. Pharmacol. 1997, 49, 446– 449, doi:10.1111/j.2042-7158.1997.tb06822.x.
41. Court, M.H. Feline Drug Metabolism and Disposition: Pharmacokinetic Evidence for Species Differences and Molecular Mechanisms. Vet. Clin. North Am. - Small Anim. Pract. 2013, 43, 1039–1054, doi:10.1016/j.cvsm.2013.05.002.
42. Johansson, I.; Ingelman-Sundberg, M. CNVs of Human Genes and Their Implication in Pharmacogenetics. Cytogenet. Genome Res. 2009, 123, 195–204, doi:10.1159/000184709.
43. Guillemette, C.; Lévesque, E.; Harvey, M.; Bellemare, J.; Menard, V. UGT Genomic Diversity: Beyond Gene Duplication. Drug Metab. Rev. 2010, 42, 24–44, doi:10.3109/03602530903210682.
44. Hutchinson, T.H.; Madden, J.C.; Naidoo, V.; Walker, C.H. Comparative Metabolism as a Key Driver of Wildlife Species Sensitivity to Human and Veterinary Pharmaceuticals. Philos. Trans. R. Soc. B Biol. Sci. 2014, 369, 20130583, doi:10.1098/rstb.2013.0583. 89
45. Kawai, Y.K.; Shinya, S.; Ikenaka, Y.; Saengtienchai, A.; Kondo, T.; Darwish, W.S.; Nakayama, S.M.M.; Mizukawa, H.; Ishizuka, M. Characterization of Function and Genetic Feature of UDPGlucuronosyltransferase in Avian Species. Comp. Biochem. Physiol. Part - C Toxicol. Pharmacol. 2019, 217, 5–14, doi:10.1016/j.cbpc.2018.11.001.
46. Hassanin, A.; Veron, G.; Ropiquet, A.; van Vuuren, B.J.; Lécu, A.; Goodman, S.M.; Haider, J.; Nguyen, T.T. Evolutionary History of Carnivora (Mammalia, Laurasiatheria) Inferred from Mitochondrial Genomes. PLoS One 2021, 16, e0240770, doi:10.1371/JOURNAL.PONE.0240770.
47. Werdelin, L.; Dehghani, R. Carnivora. In Vertebrate Paleobiology and Paleoanthropology; Springer, 2011; pp. 189–232.
48. Van Valkenburgh, B.; Wayne, R.K. Carnivores. Curr. Biol. 2010, 20, R915–R919, doi:10.1016/j.cub.2010.09.013.
49. Lambeck, R.J. Focal Species: A Multi-Species Umbrella for Nature Conservation. Conserv. Biol. 1997, 11, 849–856, doi:10.1046/J.1523- 1739.1997.96319.X.
50. Roberge, J.M.; Angelstam, P. Usefulness of the Umbrella Species Concept as a Conservation Tool. Conserv. Biol. 2004, 18, 76–85, doi:10.1111/J.1523-1739.2004.00450.X.
51. Simberloff, D. Flagships, Umbrellas, and Keystones: Is Single-Species Management Passé in the Landscape Era? Biol. Conserv. 1998, 83, 247– 257, doi:10.1016/S0006-3207(97)00081-5.
52. Adams, M.S.; Service, C.N.; Bateman, A.; Bourbonnais, M.; Artelle, K.A.; Nelson, T.; Paquet, P.C.; Levi, T.; Darimont, C.T. Intrapopulation Diversity in Isotopic Niche over Landscapes: Spatial Patterns Inform Conservation of Bear–Salmon Systems. Ecosphere 2017, 8, e01843, doi:10.1002/ecs2.1843.
53. Sergio, F.; Caro, T.; Brown, D.; Clucas, B.; Hunter, J.; Ketchum, J.; McHugh, K.; Hiraldo, F. Top Predators as Conservation Tools: Ecological Rationale, Assumptions, and Efficacy. Annu. Rev. Ecol. Evol. Syst. 2008, 39, 1–19, doi:10.1146/annurev.ecolsys.39.110707.173545.
54. Ceballos, G.; Ehrlich, P.R.; Soberón, J.; Salazar, I.; Fay, J.P. Ecology: Global Mammal Conservation: What Must We Manage? Science (80-. ). 2005, 309, 603–607, doi:10.1126/science.1114015. 90
55. Clucas, B.; McHugh, K.; Caro, T. Flagship Species on Covers of US Conservation and Nature Magazines. Biodivers. Conserv. 2008, 17, 1517–1528, doi:10.1007/S10531-008-9361-0/FIGURES/5.
56. van Valkenburgh, B.; Pang, B.; Bird, D.; Curtis, A.; Yee, K.; Wysocki, C.; Craven, B.A. Respiratory and Olfactory Turbinals in Feliform and Caniform Carnivorans: The Influence of Snout Length. Anat. Rec. 2014, 297, 2065–2079, doi:10.1002/AR.23026.
57. IUCN Red List of Threatened Species. Choice Rev. Online 2005, 43, 43- 2185-43–2185, doi:10.5860/choice.43-2185.
58. Nelson, D.R.; Kamataki, T.; Waxman, D.J.; Guengerich, F.P.; Estabrook, R.W.; Feyereisen, R.; Gonzalez, F.J.; Coon, M.J.; Gunsalus, I.C.; Gotoh, O.; et al. The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature. https://home.liebertpub.com/dna 2009, 12, 1–51, doi:10.1089/DNA.1993.12.1.
59. Zanger, U.M.; Schwab, M. Cytochrome P450 Enzymes in Drug Metabolism: Regulation of Gene Expression, Enzyme Activities, and Impact of Genetic Variation. Pharmacol. Ther. 2013, 138, 103–141, doi:10.1016/j.pharmthera.2012.12.007.
60. Ramaiahgari, S.C.; Waidyanatha, S.; Dixon, D.; DeVito, M.J.; Paules, R.S.; Ferguson, S.S. From the Cover: Three-Dimensional (3D) HepaRG Spheroid Model With Physiologically Relevant Xenobiotic Metabolism Competence and Hepatocyte Functionality for Liver Toxicity Screening. Toxicol. Sci. 2017, 159, 124–136, doi:10.1093/toxsci/kfx122.
61. Nelson, D.R.; Koymans, L.; Kamataki, T.; Stegeman, J.J.; Feyereisen, R.; Waxman, D.J.; Waterman, M.R.; Gotoh, O.; Coon, M.J.; Estabrook, R.W.; et al. P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers and Nomenclature. Pharmacogenetics 1996, 6, 1– 42, doi:10.1097/00008571-199602000-00002.
62. Zhao, M.; Ma, J.; Li, M.; Zhang, Y.; Jiang, B.; Zhao, X.; Huai, C.; Shen, L.; Zhang, N.; He, L.; et al. Cytochrome P450 Enzymes and Drug Metabolism in Humans. Int. J. Mol. Sci. 2021, 22, 12808, doi:10.3390/ijms222312808.
63. Sabbagh, A.; Marin, J.; Veyssière, C.; Lecompte, E.; Boukouvala, S.; Poloni, E.S.; Darlu, P.; Crouau-Roy, B. Rapid Birth-and-Death Evolution of the Xenobiotic Metabolizing NAT Gene Family in Vertebrates with 91 Evidence of Adaptive Selection. BMC Evol. Biol. 2013, 13, 62, doi:10.1186/1471-2148-13-62.
64. Kawashima, A.; Satta, Y. Substrate-Dependent Evolution of Cytochrome P450: Rapid Turnover of the Detoxification-Type and Conservation of the Biosynthesis-Type. PLoS One 2014, 9, e100059, doi:10.1371/journal.pone.0100059.
65. Thomas, J.H. Rapid Birth–Death Evolution Specific to Xenobiotic Cytochrome P450 Genes in Vertebrates. PLOS Genet. 2007, 3, e67, doi:10.1371/JOURNAL.PGEN.0030067.
66. Bock, K.W. Vertebrate UDP-Glucuronosyltransferases: Functional and Evolutionary Aspects. Biochem. Pharmacol. 2003, 66, 691–696, doi:10.1016/S0006-2952(03)00296-X.
67. Johnson, R.N.; O’Meally, D.; Chen, Z.; Etherington, G.J.; Ho, S.Y.W.; Nash, W.J.; Grueber, C.E.; Cheng, Y.; Whittington, C.M.; Dennison, S.; et al. Adaptation and Conservation Insights from the Koala Genome. Nat. Genet. 2018, 50, 1102–1111, doi:10.1038/s41588-018-0153-5.
68. Greenhalgh, R.; Holding, M.L.; Orr, T.J.; Henderson, J.B.; Parchman, T.L.; Matocq, M.D.; Shapiro, M.D.; Dearing, M.D. Trio-Binned Genomes of the Woodrats Neotoma Bryanti and Neotoma Lepida Reveal Novel Gene Islands and Rapid Copy Number Evolution of Xenobiotic Metabolizing Genes. Mol. Ecol. Resour. 2022, 22, 2713–2731, doi:10.1111/1755-0998.13650.
69. Watanabe, K.P.; Kawai, Y.K.; Ikenaka, Y.; Kawata, M.; Ikushiro, S.I.; Sakaki, T.; Ishizuka, M. Avian Cytochrome P450 (CYP) 1-3 Family Genes: Isoforms, Evolutionary Relationships, and MRNA Expression in Chicken Liver. PLoS One 2013, 8, e75689, doi:10.1371/journal.pone.0075689.
70. Radominska-Pandya, A.; Bratton, S.; Little, J. A Historical Overview of the Heterologous Expression of Mammalian UDP-Glucuronosyltransferase Isoforms Over the Past Twenty Years. Curr. Drug Metab. 2005, 6, 141– 160, doi:10.2174/1389200053586127.
71. Kondo, T.; Ikenaka, Y.; Nakayama, S.M.M.; Kawai, Y.K.; Mizukawa, H.; Mitani, Y.; Nomiyama, K.; Tanabe, S.; Ishizuka, M. Uridine DiphosphateGlucuronosyltransferase (UGT) 2B Subfamily Interspecies Differences in Carnivores. Toxicol. Sci. 2017, 158, 90–100, doi:10.1093/toxsci/kfx072. 92
72. Kakehi, M.; Ikenaka, Y.; Nakayama, S.M.M.; Kawai, Y.K.; Watanabe, K.P.; Mizukawa, H.; Nomiyama, K.; Tanabe, S.; Ishizuka, M. Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species. Toxicol. Sci. 2015, 147, 360–369, doi:10.1093/toxsci/kfv144.
73. Shrestha, B.; Reed, J.M.; Starks, P.T.; Kaufman, G.E.; Goldstone, J. V.; Roelke, M.E.; O’Brien, S.J.; Koepfli, K.P.; Frank, L.G.; Court, M.H. Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory. PLoS One 2011, 6, 221–237, doi:10.1371/journal.pone.0018046.
74. Genereux, D.P.; Serres, A.; Armstrong, J.; Johnson, J.; Marinescu, V.D.; Murén, E.; Juan, D.; Bejerano, G.; Casewell, N.R.; Chemnick, L.G.; et al. A Comparative Genomics Multitool for Scientific Discovery and Conservation. Nature 2020, 587, 240–245, doi:10.1038/s41586-020- 2876-6.
75. Kumar, S.; Stecher, G.; Li, M.; Knyaz, C.; Tamura, K. MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms. Mol. Biol. Evol. 2018, 35, 1547–1549, doi:10.1093/molbev/msy096.
76. Buels, R.; Yao, E.; Diesh, C.M.; Hayes, R.D.; Munoz-Torres, M.; Helt, G.; Goodstein, D.M.; Elsik, C.G.; Lewis, S.E.; Stein, L.; et al. JBrowse: A Dynamic Web Platform for Genome Visualization and Analysis. Genome Biol. 2016, 17, 1–12, doi:10.1186/S13059-016-0924-1/TABLES/3.
77. Lan, T.; Fang, D.; Li, H.; Sahu, S.K.; Wang, Q.; Yuan, H.; Zhu, Y.; Yang, Z.; Zhang, L.; Yang, S.; et al. Chromosome-Scale Genome of Masked Palm Civet (Paguma Larvata) Shows Genomic Signatures of Its Biological Characteristics and Evolution. Front. Genet. 2022, 12, 2699, doi:10.3389/fgene.2021.819493.
78. Uno, Y.; Jikuya, S.; Noda, Y.; Murayama, N.; Yamazaki, H. A Comprehensive Investigation of Dog Cytochromes P450 3A (CYP3A) Reveals A Functional Role of Newly Identified CYP3A98 in Small Intestine. Drug Metab. Dispos. 2022, in press, doi:10.1124/dmd.121.000749.
79. Honda, K.; Komatsu, T.; Koyama, F.; Kubota, A.; Kawakami, K.; Asakura, H.; Uno, Y.; Kitazawa, T.; Hiraga, T.; Teraoka, H. Expression of Two Novel Cytochrome P450 3A131 and 3A132 in Liver and Small Intestine of 93 Domestic Cats. J. Vet. Med. Sci. 2011, 73, 1489–1492, doi:10.1292/JVMS.11-0098.
80. Haley, S.L.; Lamb, J.G.; Franklin, M.R.; Constance, J.E.; Denise Dearing, M. Xenobiotic Metabolism of Plant Secondary Compounds in Juniper (Juniperus Monosperma) by Specialist and Generalist Woodrat Herbivores, Genus Neotoma. Comp. Biochem. Physiol. Part C Toxicol. Pharmacol. 2007, 146, 552–560, doi:10.1016/J.CBPC.2007.06.007.
81. Kitanovic, S.; Orr, T.J.; Spalink, D.; Cocke, G.B.; Schramm, K.; Wilderman, P.R.; Halpert, J.R.; Dearing, M.D. Role of Cytochrome P450 2B Sequence Variation and Gene Copy Number in Facilitating Dietary Specialization in Mammalian Herbivores. Mol. Ecol. 2018, 27, 723–736.
82. Mangipane, L.S.; Belant, J.L.; Lafferty, D.J.R.; Gustine, D.D.; Hiller, T.L.; Colvin, M.E.; Mangipane, B.A.; Hilderbrand, G. V. Dietary Plasticity in a Nutrient-Rich System Does Not Influence Brown Bear (Ursus Arctos) Body Condition or Denning. Polar Biol. 2018, 41, 763–772, doi:10.1007/s00300-017-2237-6.
83. Costello, C.M.; Cain, S.L.; Pils, S.; Frattaroli, L.; Haroldson, M.A.; Van Manen, F.T. Diet and Macronutrient Optimization in Wild Ursids: A Comparison of Grizzly Bears with Sympatric and Allopatric Black Bears. PLoS One 2016, 11, e0153702, doi:10.1371/journal.pone.0153702.
84. Kruuk, H.; Parish, T. Feeding Specialization of the European Badger (Meles Meles) in Scotland. J. Anim. Ecol. 1981, 50, 773–788, doi:10.2307/4136.
85. Balestrieri, A.; Remonti, L.; Saino, N.; Raubenheimer, D. The ‘Omnivorous Badger Dilemma’: Towards an Integration of Nutrition with the Dietary Niche in Wild Mammals. Mamm. Rev. 2019, 49, 324–339, doi:10.1111/MAM.12164.
86. Davies, M. Veterinary Clinical Nutrition: Success Stories: An Overview. Proc. Nutr. Soc. 2016, 75, 392–397, doi:10.1017/S002966511600029X.
87. Huang, G.; Wang, X.; Hu, Y.; Wu, Q.; Nie, Y.; Dong, J.; Ding, Y.; Yan, L.; Wei, F. Diet Drives Convergent Evolution of Gut Microbiomes in BambooEating Species. Sci. China Life Sci. 2021, 64, 88–95, doi:10.1007/s11427-020-1750-7.
88. Wei, F.; Hu, Y.; Yan, L.; Nie, Y.; Wu, Q.; Zhang, Z. Giant Pandas Are Not an Evolutionary Cul-de-Sac: Evidence from Multidisciplinary Research. Mol. Biol. Evol. 2015, 32, 4–12, doi:10.1093/MOLBEV/MSU278. 94
89. Huang, G.; Wang, L.; Li, J.; Hou, R.; Wang, M.; Wang, Z.; Qu, Q.; Zhou, W.; Nie, Y.; Hu, Y.; et al. Seasonal Shift of the Gut Microbiome Synchronizes Host Peripheral Circadian Rhythm for Physiological Adaptation to a Low-Fat Diet in the Giant Panda. Cell Rep. 2022, 38, 110203, doi:10.1016/j.celrep.2021.110203.
90. Imaoka, S.; Wedlund, P.J.; Ogawa, H.; Kimura, S.; Gonzalez, F.J.; Kim, H.Y. Identification of CYP2C23 Expressed in Rat Kidney as an Arachidonic Acid Epoxygenase. J. Pharmacol. Exp. Ther. 1993, 267, 1012–1016.
91. Shou, M.; Norcross, R.; Sandig, G.; Lu, P.; Li, Y.; Lin, Y.; Mei, Q.; Rodrigues, A.D.; Rushmore, T.H. SUBSTRATE SPECIFICITY AND KINETIC PROPERTIES OF SEVEN HETEROLOGOUSLY EXPRESSED DOG CYTOCHROMES P450. Drug Metab. Dispos. 2003, 31, 1161–1169, doi:10.1124/DMD.31.9.1161.
92. Blaisdell, J.; Goldstein, J.A.; Bai, S.A. Isolation of a New Canine Cytochrome P450 CDNA from the Cytochrome P450 2C Subfamily (CYP2C41) and Evidence for Polymorphic Differences in Its Expression. Drug Metab. Dispos. 1998, 26, 278–283.
93. Zielinski, J.; Mevissen, M. Inhibition of in Vitro Metabolism of Testosterone in Human, Dog and Horse Liver Microsomes to Investigate Species Differences. Toxicol. Vitr. 2015, 29, 468–478, doi:10.1016/J.TIV.2014.12.018.
94. Perez Jimenez, T.E.; Mealey, K.L.; Schnider, D.; Grubb, T.L.; Greene, S.A.; Court, M.H. Identification of Canine Cytochrome P-450s (CYPs) Metabolizing the Tramadol (+)-M1 and (+)-M2 Metabolites to the Tramadol (+)-M5 Metabolite in Dog Liver Microsomes. J. Vet. Pharmacol. Ther. 2018, 41, 815–824, doi:10.1111/JVP.12706.
95. Court, M.H. Canine Cytochrome P-450 Pharmacogenetics. Vet. Clin. North Am. - Small Anim. Pract. 2013, 43, 1027–1038, doi:10.1016/j.cvsm.2013.05.001.
96. Capdevila, J.H.; Falck, J.R.; Harris, R.C. Cytochrome P450 and Arachidonic Acid Bioactivation: Molecular and Functional Properties of the Arachidonate Monooxygenase. J. Lipid Res. 2000, 41, 163–181, doi:10.1016/s0022-2275(20)32049-6.
97. Miyazawa, M.; Shindo, M.; Shimada, T. Metabolism of (+)- and (−)- Limonenes to Respective Carveols and Perillyl Alcohols by CYP2C9 and 95 CYP2C19 in Human Liver Microsomes. Drug Metab. Dispos. 2002, 30, 602–607, doi:10.1124/DMD.30.5.602.
98. Jiang, R.; Yamaori, S.; Takeda, S.; Yamamoto, I.; Watanabe, K. Identification of Cytochrome P450 Enzymes Responsible for Metabolism of Cannabidiol by Human Liver Microsomes. Life Sci. 2011, 89, 165–170, doi:10.1016/J.LFS.2011.05.018.
99. Miyazawa, M.; Sugie, A.; Shimada, T. ROLES OF HUMAN CYP2A6 AND 2B6 AND RAT CYP2C11 AND 2B1 IN THE 10-HYDROXYLATION OF (–)-VERBENONE BY LIVER MICROSOMES. Drug Metab. Dispos. 2003, 31, 1049–1053, doi:10.1124/DMD.31.8.1049.
100. Kendall, K.C. Use of Pine Nuts by Grizzly and Black Bears in the Yellowstone Area. Bears Their Biol. Manag. 1983, 5, 166, doi:10.2307/3872534.
101. Felicetti, L.A.; Schwartz, C.C.; Rye, R.O.; Haroldson, M.A.; Gunther, K.A.; Phillips, D.L.; Robbins, C.T. Use of Sulfur and Nitrogen Stable Isotopes to Determine the Importance of Whitebark Pine Nuts to Yellowstone Grizzly Bears. Can. J. Zool. 2003, 81, 763–770, doi:10.1139/z03-054.
102. Zulak, K.G.; Bohlmann, J. Terpenoid Biosynthesis and Specialized Vascular Cells of Conifer Defense. J. Integr. Plant Biol. 2010, 52, 86–97, doi:10.1111/J.1744-7909.2010.00910.X.
103. Kopaczyk, J.M.; Warguła, J.; Jelonek, T. The Variability of Terpenes in Conifers under Developmental and Environmental Stimuli. Environ. Exp. Bot. 2020, 180, 104197, doi:10.1016/J.ENVEXPBOT.2020.104197.
104. Karakus, E.; Prinzinger, C.; Leiting, S.; Geyer, J. Sequencing of the Canine Cytochrome P450 CYP2C41 Gene and Genotyping of Its Polymorphic Occurrence in 36 Dog Breeds. Front. Vet. Sci. 2021, 8, 663175, doi:10.3389/fvets.2021.663175.
105. DeLozier, T.C.; Tsao, C.C.; Coulter, S.J.; Foley, J.; Bradbury, J.A.; Zeldin, D.C.; Goldstein, J.A. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products. J. Pharmacol. Exp. Ther. 2004, 310, 845–854, doi:10.1124/jpet.104.067819.
106. Capdevila, J.; Wang, W. Role of Cytochrome P450 Epoxygenase in Regulating Renal Membrane Transport and Hypertension. Curr. Opin. Nephrol. Hypertens. 2013, 22, 163–169, doi:10.1097/MNH.0b013e32835d911e. 96
107. Ingelman-Sundberg, M. Human Drug Metabolising Cytochrome P450 Enzymes: Properties and Polymorphisms. Naunyn. Schmiedebergs. Arch. Pharmacol. 2004, 369, 89–104, doi:10.1007/S00210-003-0819-Z.
108. Wright, W.C.; Chenge, J.; Chen, T. Structural Perspectives of the CYP3A Family and Their Small Molecule Modulators in Drug Metabolism. Liver Res. 2019, 3, 132–142, doi:10.1016/J.LIVRES.2019.08.001.
109. Fraser, D.J.; Feyereisen, R.; Harlow, G.R.; Halpert, J.R. Isolation, Heterologous Expression and Functional Characterization of a Novel Cytochrome P450 3A Enzyme from a Canine Liver CDNA Library. J. Pharmacol. Exp. Ther. 1997, 283, 1425–1432.
110. Locuson, C.W.; Ethell, B.T.; Voice, M.; Lee, D.; Feenstra, K.L. Evaluation of Escherichia Coli Membrane Preparations of Canine CYP1A1, 2B11, 2C21, 2C41, 2D15, 3A12, and 3A26 with Coexpressed Canine Cytochrome P450 Reductase. Drug Metab. Dispos. 2009, 37, 457–461, doi:10.1124/DMD.108.025312.
111. Martinez, S.E.; Shi, J.; Zhu, H.J.; Jimenez, T.E.P.; Zhu, Z.; Court, M.H. Absolute Quantitation of Drug-Metabolizing Cytochrome P450 Enzymes and Accessory Proteins in Dog Liver Microsomes Using Label-Free Standard-Free Analysis Reveals Interbreed Variability. Drug Metab. Dispos. 2019, 47, 1314–1324, doi:10.1124/dmd.119.088070.
112. Sugiyama, S.; Uno, Y.; Amano, T.; Kitazawa, T.; Teraoka, H. Genetic Diversity of Cytochrome P450 3A with Different Metabolic Activity in Domestic Cats. J. Vet. Med. Sci. 2019, 81, 598–600, doi:10.1292/JVMS.18-0692.
113. Visser, M.; Weber, K.L.; Lyons, L.A.; Rincon, G.; Boothe, D.M.; Merritt, D.A. Identification and Quantification of Domestic Feline Cytochrome P450 Transcriptome across Multiple Tissues. J. Vet. Pharmacol. Ther. 2019, 42, 7–15, doi:10.1111/JVP.12708.
114. Fu, P.P. Pyrrolizidine Alkaloids: Metabolic Activation Pathways Leading to Liver Tumor Initiation. Chem. Res. Toxicol. 2017, 30, 81–93, doi:10.1021/ACS.CHEMRESTOX.6B00297/ASSET/IMAGES/LARGE/TX2016-002972_0007.JPEG.
115. Liu, Y. Incorporation of Absorption and Metabolism into Liver Toxicity Prediction for Phytochemicals: A Tiered in Silico QSAR Approach. Food Chem. Toxicol. 2018, 118, 409–415, doi:10.1016/J.FCT.2018.05.039. 97
116. Huan, J.Y.; Miranda, C.L.; Buhler, D.R.; Cheeke, P.R. The Roles of CYP3A and CYP2B Isoforms in Hepatic Bioactivation and Detoxification of the Pyrrolizidine Alkaloid Senecionine in Sheep and Hamsters. Toxicol. Appl. Pharmacol. 1998, 151, 229–235, doi:10.1006/TAAP.1998.8482.
117. Ono, Y.; Sugiyama, S.; Matsushita, M.; Kitazawa, T.; Amano, T.; Uno, Y.; Ikushiro, S.; Teraoka, H. Limited Expression of Functional Cytochrome P450 2c Subtypes in the Liver and Small Intestine of Domestic Cats. Xenobiotica 2019, 49, 627–635, doi:10.1080/00498254.2018.1483543.
118. Tanaka, N.; Shinkyo, R.; Sakaki, T.; Kasamastu, M.; Imaoka, S.; Funae, Y.; Yokota, H. Cytochrome P450 2E Polymorphism in Feline Liver. Biochim. Biophys. Acta - Gen. Subj. 2005, 1726, 194–205, doi:10.1016/j.bbagen.2005.08.004.
119. Khidkhan, K.; Mizukawa, H.; Ikenaka, Y.; Nakayama, S.M.M.; Nomiyama, K.; Yokoyama, N.; Ichii, O.; Darwish, W.S.; Takiguchi, M.; Tanabe, S.; et al. Tissue Distribution and Characterization of Feline Cytochrome P450 Genes Related to Polychlorinated Biphenyl Exposure. Comp. Biochem. Physiol. Part C Toxicol. Pharmacol. 2019, 226, 108613, doi:10.1016/J.CBPC.2019.108613.
120. Kumar, S.; Stecher, G.; Suleski, M.; Blair Hedges, S. TimeTree: A Resource for Timelines, Timetrees, and Divergence Times. Mol. Biol. Evol. 2017, 34, 1812–1819, doi:10.1093/MOLBEV/MSX116.
121. Rezaei Khozani, A.; Kaboli, M.; Ashrafi, S.; Akbari, H. Survey Diet of Asiatic Cheetah Acinonyx Jubatus Venaticus by Scat Analysis Method in Bafgh Protected Area, Central Iran. J. Anim. Environ. 2016, 8, 1–8.
122. Mills, M.G.L.; Broomhall, L.S.; Du Toit, J.T. Cheetah Acinonyx Jubatus Feeding Ecology in the Kruger National Park and a Comparison across African Savanna Habitats: Is the Cheetah Only a Successful Hunter on Open Grassland Plains? Wildlife Biol. 2004, 10, 177–186, doi:10.2981/wlb.2004.024.
123. Duffey, E. The Giant Pandas of Wolong. Biol. Conserv. 1986, 37, 95–96, doi:10.1016/0006-3207(86)90042-x.
124. Gudmundson, C.J.; Zeppelin, T.K.; Ream, R.R. Application of Two Methods for Determining Diet of Northern Fur Seals (Callorhinus Ursinus). Fish. Bull. 2006, 104, 445–455.
125. Berta, A.; Churchill, M.; Boessenecker, R.W. The Origin and Evolutionary Biology of Pinnipeds: Seals, Sea Lions, and Walruses. Annu. Rev. Earth 98 Planet. Sci. 2018, 46, 203–228, doi:10.1146/annurev-earth-082517- 010009.
126. Clark, C.W.; Garland, E.C. Ethology and Behavioral Ecology of Mysticetes Ethology and Behavioral Ecology of Marine. In Ethology and Behavioral Ecology of Marine Mammals; Costa, D.P., McHuron, E.A., Eds.; Ethology and Behavioral Ecology of Marine Mammals; Springer International Publishing: Cham, 2022; p. 384 ISBN 9783030984489.
127. Pauly, D.; Trites, A.W.; Capuli, E.; Christensen, V. Diet Composition and Trophic Levels of Marine Mammals. ICES J. Mar. Sci. 1998, 55, 467–481, doi:10.1006/jmsc.1997.0280.
128. Bosch, G.; Hagen-Plantinga, E.A.; Hendriks, W.H. Dietary Nutrient Profiles of Wild Wolves: Insights for Optimal Dog Nutrition? Br. J. Nutr. 2015, 113, S40–S54, doi:10.1017/S0007114514002311.
129. Soars, M.G.; Riley, R.J.; Findlay, K.A.B.; Coffey, M.J.; Burchell, B. Evidence for Significant Differences in Microsomal Drug Glucuronidation by Canine and Human Liver and Kidney. Drug Metab. Dispos. 2001, 29, 121–126.
130. Baker, D.H.; Czarnecki-Maulden, G.L. Comparative Nutrition of Cats and Dogs. Annu. Rev. Nutr. 1991, 11, 239–263, doi:10.1146/annurev.nu.11.070191.001323.
131. Montanari, S. Discrimination Factors of Carbon and Nitrogen Stable Isotopes in Meerkat Feces. PeerJ 2017, 2017, e3436, doi:10.7717/peerj.3436.
132. Brox, B.W.; Edwards, K.; Buist, N.A.; Macaskill, A.C. Investigating Food Preference in Zoo-Housed Meerkats. Zoo Biol. 2021, 40, 517–526, doi:10.1002/ZOO.21640.
133. Johnson, C.K.; Tinker, M.T.; Estes, J.A.; Conrad, P.A.; Staedler, M.; Miller, M.A.; Jessup, D.A.; Mazet, J.A.K. Prey Choice and Habitat Use Drive Sea Otter Pathogen Exposure in a Resource-Limited Coastal System. Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 2242–2247, doi:10.1073/PNAS.0806449106/SUPPL_FILE/0806449106SI.PDF.
134. Rand, K.; McDermott, S.; Logerwell, E.; Matta, M.E.; Levine, M.; Bryan, D.R.; Spies, I.B.; Loomis, T. Higher Aggregation of Key Prey Species Associated with Diet and Abundance of the Steller Sea Lion Eumetopias Jubatus across the Aleutian Islands. Mar. Coast. Fish. 2019, 11, 472– 486, doi:10.1002/mcf2.10096. 99
135. Edinboro, C.H.; Scott-Moncrieff, J.C.; Janovitz, E.; Thacker, H.L.; Glickman, L.T. Epidemiologic Study of Relationships between Consumption of Commercial Canned Food and Risk of Hyperthyroidism in Cats. J. Am. Vet. Med. Assoc. 2004, 224, 879–886, doi:10.2460/javma.2004.224.879.
136. Hammill, M.O.; Stenson, G.B. Estimated Prey Consumption by Harp Seals (Phoca Groenlandica), Hooded Seals (Cystophora Cristata), Grey Seals (Halichoerus Grypus) and Harbour Seals (Phoca Vitulina) in Atlantic Canada. J. Northwest Atl. Fish. Sci. 2000, 26, 1–23, doi:10.2960/J.v26.a1.
137. Alam, M.S.; Khan, J.A. Food Habits of Striped Hyena (Hyaena Hyaena) in a Semi-Arid Conservation Area of India. J. Arid Land 2015, 7, 860–866, doi:10.1007/s40333-015-0007-2.
138. Bhandari, S.; Morley, C.; Aryal, A.; Shrestha, U.B. The Diet of the Striped Hyena in Nepal’s Lowland Regions. Ecol. Evol. 2020, 10, 7953–7962, doi:10.1002/ECE3.6223.
139. Goetz, K.T.; Burns, J.M.; Hückstӓdt, L.A.; Shero, M.R.; Costa, D.P. Temporal Variation in Isotopic Composition and Diet of Weddell Seals in the Western Ross Sea. Deep. Res. Part II Top. Stud. Oceanogr. 2017, 140, 36–44, doi:10.1016/J.DSR2.2016.05.017.
140. Cote, D.; Stewart, H.M.J.; Gregory, R.S.; Gosse, J.; Reynolds, J.J.; Stenson, G.B.; Miller, E.H. Prey Selection by Marine-Coastal River Otters (Lontra Canadensis) in Newfoundland, Canada. J. Mammal. 2008, 89, 1001–1011, doi:10.1644/07-MAMM-A-192.1.
141. Day, C.C.; Westover, M.D.; McMillan, B.R. Seasonal Diet of the Northern River Otter (Lontra Canadensis): What Drives Prey Selection? Can. J. Zool. 2015, 93, 197–205, doi:10.1139/cjz-2014-0218.
142. Krawczyk, A.J.; Bogdziewicz, M.; Majkowska, K.; Glazaczow, A. Diet Composition of the Eurasian Otter Lutra Lutra in Different Freshwater Habitats of Temperate Europe: A Review and Meta-Analysis. Mamm. Rev. 2016, 46, 106–113, doi:10.1111/mam.12054.
143. Burstahler, C.M.; Terwissen, C. V.; Roth, J.D. Latitudinal Gradient in Cortisol Concentrations in Canada Lynx (Lynx Canadensis) Is Not Explained by Diet. Can. J. Zool. 2019, 97, 748–753, doi:10.1139/CJZ2018-0204/SUPPL_FILE/CJZ-2018-0204SUPPLA.DOCX. 100
144. Parker, G.R.; Maxwell, J.W.; Morton, L.D.; Smith, G.E.J. The Ecology of the Lynx ( Lynx Canadensis) on Cape Breton Island ( Snowshoe Hare Lepus Americanus). Can. J. Zool. 1983, 61, 770–786, doi:10.1139/z83- 102.
145. Cleary, G.P.; Corner, L.A.L.; O’Keeffe, J.; Marples, N.M. The Diet of the Badger Meles Meles in the Republic of Ireland. Mamm. Biol. 2009, 74, 438–447, doi:10.1016/j.mambio.2009.07.003.
146. Rita, D.; Drago, M.; Galimberti, F.; Cardona, L. Temporal Consistency of Individual Trophic Specialization in Southern Elephant Seals Mirounga Leonina. Mar. Ecol. Prog. Ser. 2017, 585, 229–242, doi:10.3354/MEPS12411.
147. Spurlin, S.M.; Peterson, S.H.; Crocker, D.E.; Costa, D.P. Nitrogen and Carbon Stable-Isotope Ratios Change in Adult Northern Elephant Seals (Mirounga Angustirostris) during the Breeding and Molting Fasts. Mar. Mammal Sci. 2019, 35, 707–717, doi:10.1111/MMS.12558.
148. Condit, R.; Le Boeuf, B.J. Feeding Habits and Feeding Grounds of the Northern Elephant Seal. J. Mammal. 1984, 65, 281–290, doi:10.2307/1381167.
149. Dell’Arte, G.L.; Laaksonen, T.; Norrdahl, K.; Korpimäki, E. Variation in the Diet Composition of a Generalist Predator, the Red Fox, in Relation to Season and Density of Main Prey. Acta Oecologica 2007, 31, 276–281, doi:10.1016/J.ACTAO.2006.12.007.
150. McDonald, R.A.; Webbon, C.; Harris, S. The Diet of Stoats (Mustela Erminea) and Weasels (Mustela Nivalis) in Great Britain. J. Zool. 2000, 252, 363–371, doi:10.1111/J.1469-7998.2000.TB00631.X.
151. Smith, G.P.; Ragg, J.R.; Waldrup, K.A.; Moller, H. Diet of Feral Ferrets (Mustela Furo) from Pastoral Habitats in Otago and Southland, New Zealand. New Zeal. J. Zool. 1995, 22, 363–369, doi:10.1080/03014223.1995.9518054.
152. Vinke, C.M.; Schoemaker, N.J. The Welfare of Ferrets (Mustela Putorius Furo T): A Review on the Housing and Management of Pet Ferrets. Appl. Anim. Behav. Sci. 2012, 139, 155–168, doi:10.1016/J.APPLANIM.2012.03.016.
153. Krawczyk, A.J.; Bogdziewicz, M.; Czyz, M.J. Diet of the American Mink Neovison Vison in an Agricultural Landscape in Western Poland. Folia Zool. 2013, 62, 304–310, doi:10.25225/fozo.v62.i4.a8.2013. 101
154. Magnusdottir, R.; von Schmalensee, M.; Stefansson, R.A.; Macdonald, D.W.; Hersteinsson, P. A Foe in Woe: American Mink (Neovison Vison) Diet Changes during a Population Decrease. Mamm. Biol. 2014, 79, 58– 63, doi:10.1016/j.mambio.2013.08.002.
155. Robinson, S.; Barbieri, M.; Johanos, T. The Hawaiian Monk Seal: Ethology Applied to Endangered Species Conservation and Recovery. In Ethology and Behavioral Ecology of Marine Mammals.; Springer, Cham, 2022; pp. 599–635.
156. Sheffield, G.; Grebmeier, J.M. Pacific Walrus (Odobenus Rosmarus Divergens):Differential Prey Digestion and Diet. Mar. Mammal Sci. 2009, 25, 761–777, doi:10.1111/J.1748-7692.2009.00316.X.
157. Clark, C.T.; Horstmann, L.; Vernal, A. de; Jensen, A.M.; Misarti, N. Pacific Walrus Diet across 4000 Years of Changing Sea Ice Conditions. Quat. Res. 2022, 108, 26–42, doi:10.1017/QUA.2018.140.
158. Beukes, M.; Radloff, F.G.T.; Ferreira, S.M. Estimating Lion’s Prey Species Profile in an Arid Environment. J. Zool. 2017, 303, 136–144, doi:10.1111/JZO.12474.
159. Bothma, J. du P.; Walker, C. The African Lion. Larg. Carniv. African Savannas 1999, 22–59.
160. Kshettry, A.; Vaidyanathan, S.; Athreya, V. Diet Selection of Leopards (Panthera Pardus) in a Human-Use Landscape in North-Eastern India. Trop. Conserv. Sci. 2018, 11, doi:10.1177/1940082918764635.
161. Andheria, A.P.; Karanth, K.U.; Kumar, N.S. Diet and Prey Profiles of Three Sympatric Large Carnivores in Bandipur Tiger Reserve, India. J. Zool. 2007, 273, 169–175, doi:10.1111/j.1469-7998.2007.00310.x.
162. Hayward, M.W.; Jedrzejewski, W.; Jedrzewska, B. Prey Preferences of the Tiger P Anthera Tigris. J. Zool. 2012, 286, 221–231, doi:10.1111/j.1469-7998.2011.00871.x.
163. Biswas, S.; Sankar, K. Prey Abundance and Food Habit of Tigers (Panthera Tigris Tigris) in Pench National Park, Madhya Pradesh, India. J. Zool. 2002, 256, 411–420, doi:10.1017/S0952836902000456.
164. Toth, J.; Evert, S.; Zimmermann, E.; Sullivan, M.; Dotts, L.; Able, K.W.; Hagan, R.; Slocum, C. Annual Residency Patterns and Diet of Phoca Vitulina Concolor (Western Atlantic Harbor Seal) in a Southern New Jersey Estuary. Northeast. Nat. 2018, 25, 627–645, doi:10.1656/045.025.0407. 102
165. Ganguly, D.; Adhya, T. How Fishing Cats Prionailurus Viverrinus Bennett, 1833 Fish: Describing a Felid’s Strategy to Hunt Aquatic Prey. Mammalia 2022, 86, 182–189, doi:10.1515/MAMMALIA-2020- 0133/DOWNLOADASSET/SUPPL/J_MAMMALIA-2020- 0133_SUPPL_003.JPG.
166. Grassman, L.I.; Tewes, M.E.; Silvy, N.J.; Kreetiyutanont, K. Spatial Organization and Diet of the Leopard Cat (Prionailurus Bengalensis) in North-Central Thailand. J. Zool. 2005, 266, 45–54, doi:10.1017/S095283690500659X.
167. Rau, J.R.; Jiménez, J.E. Diet of Puma (Puma Concolor, Carnivora: Felidae) in Coastal and Andean Ranges of Southern Chile. Stud. Neotrop. Fauna Environ. 2002, 37, 201–205, doi:10.1076/snfe.37.3.201.8567.
168. Aranda, M.; Sánchez-Cordero, V. Prey Spectra of Jaguar (Panthera Onca) and Puma (Puma Concolor) in Tropical Forests of Mexico. Stud. Neotrop. Fauna Environ. 1996, 31, 65–67, doi:10.1076/SNFE.31.2.65.13334.
169. Tófoli, C.F.; Rohe, F.; Setz, E.Z.F. Jaguarundi (Puma Yagouaroundi) (Geoffroy, 1803) (Carnivora, Felidae) Food Habits in a Mosaic of Atlantic Rainforest and Eucalypt Plantations of Southeastern Brazil. Brazilian J. Biol. 2009, 69, 871–877, doi:10.1590/S1519-69842009000400015.
170. Bianchi, R. de C.; Rosa, A.F.; Gatti, A.; Mendes, S.L. Diet of Margay, Leopardus Wiedii, and Jaguarundi, Puma Yagouaroundi, (Carnivora: Felidae) in Atlantic Rainforest, Brazil. Zoologia 2011, 28, 127–132, doi:10.1590/S1984-46702011000100018.
171. Merkle, J.A.; Polfus, J.L.; Derbridge, J.J.; Heinemeyer, K.S. Dietary Niche Partitioning among Black Bears, Grizzly Bears, and Wolves in a Multiprey Ecosystem. Can. J. Zool. 2017, 95, 663–671, doi:10.1139/cjz-2016-0258.
172. Kirby, R.; Alldredge, M.W.; Pauli, J.N. The Diet of Black Bears Tracks the Human Footprint across a Rapidly Developing Landscape. Biol. Conserv. 2016, 200, 51–59, doi:10.1016/J.BIOCON.2016.05.012.
173. Hatch, K.A.; Kester, K.A.; Auger, J.; Roeder, B.L.; Bunnell, K.; Black, H.L. The Effect of Sex, Age, and Location on Carnivory in Utah Black Bears (Ursus Americanus). Oecologia 2019, 189, 931–937, doi:10.1007/S00442-019-04385-1.
174. Matsubayashi, J.; Otsubo, K.; Morimoto, J.O.; Nakamura, F.; Nose, T.; Tayasu, I. Feeding Habits May Explain the Morphological Uniqueness of 103 Brown Bears on Etorofu Island, Southern Kuril Islands in East Asia. Biol. J. Linn. Soc. 2016, 119, 99–105, doi:10.1111/BIJ.12798.
175. Mangipane, L.S.; Lafferty, D.J.R.; Joly, K.; Sorum, M.S.; Cameron, M.D.; Belant, J.L.; Hilderbrand, G. V.; Gustine, D.D. Dietary Plasticity and the Importance of Salmon to Brown Bear (Ursus Arctos) Body Size and Condition in a Low Arctic Ecosystem. Polar Biol. 2020, 43, 825–833, doi:10.1007/s00300-020-02690-7.
176. Johnson, A.C.; Hobson, K.A.; Lunn, N.J.; McGeachy, D.; Richardson, E.S.; Derocher, A.E. Temporal and Intra-Population Patterns in Polar Bear Foraging Ecology in Western Hudson Bay. Mar. Ecol. Prog. Ser. 2019, 619, 187–199, doi:10.3354/MEPS12933.
177. Elmhagen, B.; Tannerfeldt, M.; Verucci, P.; Angerbjörn, A. The Arctic Fox ( Alopex Lagopus ): An Opportunistic Specialist . J. Zool. 2000, 251, 139–149, doi:10.1111/j.1469-7998.2000.tb00599.x.
178. Frafjord, K. Food Habits of Arctic Foxes (Alopex Lagopus) on the Western Coast of Svalbard. Arctic 1993, 46, 49–54, doi:10.14430/arctic1321.
179. Baltrūnaitė, L. Diet and Winter Habitat Use of the Red Fox, Pine Marten and Raccoon Dog in Dzūkija National Park, Lithuania. Acta Zool. Litu. 2006, 16, 46–53, doi:10.1080/13921657.2006.10512709.
180. Castañeda, I.; Doherty, T.S.; Fleming, P.A.; Stobo-Wilson, A.M.; Woinarski, J.C.Z.; Newsome, T.M. Variation in Red Fox Vulpes Vulpes Diet in Five Continents. Mamm. Rev. 2022, 52, 328–342, doi:10.1111/MAM.12292.
181. Weise, M.J.; Harvey, J.T. Temporal Variability in Ocean Climate and California Sea Lion Diet and Biomass Consumption: Implications for Fisheries Management. Mar. Ecol. Prog. Ser. 2008, 373, 157–172, doi:10.3354/MEPS07737.
182. Bailey, K.M.; Ainley, D.G. The Dynamics of California Sea Lion Predation on Pacific Hake. Fish. Res. 1981, 1, 163–176, doi:10.1016/0165- 7836(81)90018-7.
183. Andrew Williams, J.; Ring, B.J.; Cantrell, V.E.; Campanale, K.; Jones, D.R.; Hall, S.D.; Wrighton, S.A. Differential Modulation of UDPGlucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3- Glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes. Drug Metab. Dispos. 2002, 30, 1266–1273, doi:10.1124/dmd.30.11.1266. 104
184. Chowdhury, J.R.; Kondapalli, R.; Chowdhury, N.R. Gunn Rat: A Model for Inherited Deficiency of Bilirubin Glucuronidation. Adv. Vet. Sci. Comp. Med. 1993, 37, 149–173.
185. Lépine, J.; Bernard, O.; Plante, M.; Têtu, B.; Pelletier, G.; Labrie, F.; Bélanger, A.; Guillemette, C. Specificity and Regioselectivity of the Conjugation of Estradiol, Estrone, and Their Catecholestrogen and Methoxyestrogen Metabolites by Human Uridine DiphosphoGlucuronosyltransferases Expressed in Endometrium. J. Clin. Endocrinol. Metab. 2004, 89, 5222–5232, doi:10.1210/jc.2004-0331.
186. Bock, K.W. Roles of Human UDP-Glucuronosyltransferases in Clearance and Homeostasis of Endogenous Substrates, and Functional Implications. Biochem. Pharmacol. 2015, 96, 77–82, doi:10.1016/j.bcp.2015.04.020.
187. Tampal, N.; Lehmler, H.J.; Espandiari, P.; Malmberg, T.; Robertson, L.W. Glucuronidation of Hydroxylated Polychlorinated Biphenyls (PCBs). Chem. Res. Toxicol. 2002, 15, 1259–1266, doi:10.1021/tx0200212.
188. Daidoji, T.; Gozu, K.; Iwano, H.; Inoue, H.; Yokota, H. UDPGlucuronosyltransferase Isoforms Catalyzing Glucuronidation of HydroxyPolychlorinated Biphenyls in Rat. Drug Metab. Dispos. 2005, 33, 1466– 1476, doi:10.1124/dmd.105.004416.
189. Kasai, N.; Sakaki, T.; Shinkyo, R.; Ikushiro, S.I.; Iyanagi, T.; Kamao, M.; Okano, T.; Ohta, M.; Inouye, K. Sequential Metabolism of 2,3,7- Trichlorodibenzo-p-Dioxin (2,3,7-TriCDD) by Cytochrome P450 and UDPGlucuronosyltransferase in Human Liver Microsomes. Drug Metab. Dispos. 2004, 32, 870–875, doi:10.1124/dmd.32.8.870.
190. Rowland, A.; Miners, J.O.; Mackenzie, P.I. The UDPGlucuronosyltransferases: Their Role in Drug Metabolism and Detoxification. Int. J. Biochem. Cell Biol. 2013, 45, 1121–1132, doi:10.1016/j.biocel.2013.02.019.
191. Guillemette, C.; Lévesque, É.; Rouleau, M. Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications. Clin. Pharmacol. Ther. 2014, 96, 324–339, doi:10.1038/clpt.2014.126.
192. Mackenzie, P.I.; Bock, K.W.; Burchell, B.; Guillemette, C.; Ikushiro, S.; Iyanagi, T.; Miners, J.O.; Owens, I.S.; Nebert, D.W. Nomenclature Update for the Mammalian UDP Glycosyltransferase (UGT) Gene Superfamily. Pharmacogenet. Genomics 2005, 15, 677–685, doi:10.1097/01.fpc.0000173483.13689.56. 105
193. Mackenzie, P.I.; Owens, I.S.; Burchell, B.; Bock, K.W.; Bairoch, A.; Bélanger, A.; Fournel-Gigleux, S.; Green, M.; Hum, D.W.; Iyanagi, T.; et al. The UDP Glycosyltransferase Gene Superfamily: Recommended Nomenclature Update Based on Evolutionary Divergence. Pharmacogenetics 1997, 7, 255–269, doi:10.1097/00008571-199708000- 00001.
194. Li, C.; Wu, Q. Adaptive Evolution of Multiple-Variable Exons and Structural Diversity of Drug-Metabolizing Enzymes. BMC Evol. Biol. 2007, 7, 69, doi:10.1186/1471-2148-7-69.
195. Yuan, Y.; Zhang, Y.; Zhang, P.; Liu, C.; Wang, J.; Gao, H.; Rus Hoelzel, A.; Seim, I.; Lv, M.; Lin, M.; et al. Comparative Genomics Provides Insights into the Aquatic Adaptations of Mammals. Proc. Natl. Acad. Sci. U. S. A. 2021, 118, e2106080118, doi:10.1073/pnas.2106080118.
196. Bock, K.W. The UDP-Glycosyltransferase (UGT) Superfamily Expressed in Humans, Insects and Plants: Animal-Plant Arms-Race and CoEvolution. Biochem. Pharmacol. 2016, 99, 11–17, doi:10.1016/j.bcp.2015.10.001.
197. Gonzalez, F.J.; Nebert, D.W. Evolution of the P450 Gene Superfamily:. Animal-Plant “Warfare”, Molecular Drive and Human Genetic Differences in Drug Oxidation. Trends Genet. 1990, 6, 182–186, doi:10.1016/0168- 9525(90)90174-5.
198. Wöll, S.; Kim, S.H.; Greten, H.J.; Efferth, T. Animal Plant Warfare and Secondary Metabolite Evolution. Nat. Products Bioprospect. 2013, 3, 1–7, doi:10.1007/s13659-013-0004-0.
199. Xing, X.; Ai, C.; Wang, T.; Li, Y.; Liu, H.; Hu, P.; Wang, G.; Liu, H.; Wang, H.; Zhang, R.; et al. The First High-Quality Reference Genome of Sika Deer Provides Insights for High-Tannin Adaptation. Genomics. Proteomics Bioinformatics 2022, in press, doi:10.1016/j.gpb.2022.05.008.
200. Kawai, Y.K.; Ikenaka, Y.; Ishizuka, M.; Kubota, A. The Evolution of UDPGlycosyl/Glucuronosyltransferase 1E (UGT1E) Genes in Bird Lineages Is Linked to Feeding Habits but UGT2 Genes Is Not. PLoS One 2018, 13, e0205266, doi:10.1371/JOURNAL.PONE.0205266.
201. Kawai, Y.K.; Sano, K.; Ikenaka, Y.; Nakayama, S.M.M.; Kondo, M.; Kubota, A.; Ishizuka, M. Evolutionary History of Mammalian UDPGlucuronosyltransferase (UGT)1 and UGT2 Families: The Emergence of UGT2B Subfamily in Eutherians after the Diversification of Flowering 106 Plants. bioRxiv 2021, 2021.08.20.457063, doi:10.1101/2021.08.20.457063.
202. Baltrūnaitė, L. Diet Composition of the Red Fox ( Vulpes Vulpes L.), Pine Marten ( Martes Martes L.) and Raccoon Dog ( Nyctereutes Procyonoides Gray) in Clay Plain Landscape, Lithuania . Acta Zool. Litu. 2002, 12, 362–368, doi:10.1080/13921657.2002.10512525.
203. Hilderbrand, G. V.; Farley, S.D.; Robbins, C.T.; Hanley, T.A.; Titus, K.; Servheen, C. Use of Stable Isotopes to Determine Diets of Living and Extinct Bears. Can. J. Zool. 1996, 74, 2080–2088, doi:10.1139/z96-236.
204. Jiangzuo, Q.; Flynn, J.J. The Earliest Ursine Bear Demonstrates the Origin of Plant-Dominated Omnivory in Carnivora. iScience 2020, 23, 101235, doi:10.1016/J.ISCI.2020.101235.
205. Lazarus, M.; Sekovanić, A.; Orct, T.; Reljić, S.; Kusak, J.; Jurasović, J.; Huber, Đ. Apex Predatory Mammals as Bioindicator Species in Environmental Monitoring of Elements in Dinaric Alps (Croatia). Environ. Sci. Pollut. Res. 2017, 24, 23977–23991, doi:10.1007/s11356-017-0008- 0.
206. Gagliano, J.; Anselmo-Moreira, F.; Sala-Carvalho, W.R.; Furlan, C.M. What Is Known about the Medicinal Potential of Bamboo? Adv. Tradit. Med. 2022, 22, 467–495, doi:10.1007/s13596-020-00536-5.
207. Marsh, K.J.; Wallis, I.R.; Andrew, R.L.; Foley, W.J. The Detoxification Limitation Hypothesis: Where Did It Come from and Where Is It Going? J. Chem. Ecol. 2006, 32, 1247–1266, doi:10.1007/s10886-006-9082-3.
208. Sorensen, J.S.; Dearing, M.D. Elimination of Plant Toxins by Herbivorous Woodrats: Revisiting an Explanation for Dietary Specialization in Mammalian Herbivores. Oecologia 2003, 134, 88–94, doi:10.1007/s00442-002-1085-3.
209. Zhu, L.; Wu, Q.; Dai, J.; Zhang, S.; Wei, F. Evidence of Cellulose Metabolism by the Giant Panda Gut Microbiome. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 17714–17719, doi:10.1073/PNAS.1017956108/SUPPL_FILE/SAPP.PDF.
210. Doncaster, C.P.; Dickman, C.R.; Macdonald, D.W. Feeding Ecology of Red Foxes (Vulpes Vulpes) in the City of Oxford, England. J. Mammal. 1990, 71, 188–194, doi:10.2307/1382166.
211. Soe, E.; Davison, J.; Süld, K.; Valdmann, H.; Laurimaa, L.; Saarma, U. Europe-Wide Biogeographical Patterns in the Diet of an Ecologically and 107 Epidemiologically Important Mesopredator, the Red Fox Vulpes Vulpes: A Quantitative Review. Mamm. Rev. 2017, 47, 198–211, doi:10.1111/MAM.12092.
212. Westbury, M. V.; Le Duc, Di.; Duchêne, D.A.; Krishnan, A.; Prost, S.; Rutschmann, S.; Grau, J.H.; Dalén, L.; Weyrich, A.; Norén, K.; et al. Ecological Specialization and Evolutionary Reticulation in Extant Hyaenidae. Mol. Biol. Evol. 2021, 38, 3884–3897, doi:10.1093/molbev/msab055.
213. Buckley, D.B.; Klaassen, C.D. Tissue- and Gender-Specific MRNA Expression of UDP-Glucuronosyltransferases (UGTs) in Mice. Drug Metab. Dispos. 2007, 35, 121–127, doi:10.1124/dmd.106.012070.
214. Sneitz, N.; Court, M.H.; Zhang, X.; Laajanen, K.; Yee, K.K.; Dalton, P.; Ding, X.; Finel, M. Human UDP-Glucuronosyltransferase UGT2A2: CDNA Construction, Expression, and Functional Characterization in Comparison with UGT2A1 and UGT2A3. Pharmacogenet. Genomics 2009, 19, 923– 934, doi:10.1097/FPC.0b013e3283330767.
215. Redmon, J.M.; Shrestha, B.; Cerundolo, R.; Court, M.H. Soy Isoflavone Metabolism in Cats Compared with Other Species: Urinary Metabolite Concentrations and Glucuronidation by Liver Microsomes. Xenobiotica 2016, 46, 406–415, doi:10.3109/00498254.2015.1086038.
216. Van Beusekom, C.D.; Fink-Gremmels, J.; Schrickx, J.A. Comparing the Glucuronidation Capacity of the Feline Liver with Substrate-Specific Glucuronidation in Dogs. J. Vet. Pharmacol. Ther. 2014, 37, 18–24, doi:10.1111/jvp.12067.
217. Owens, I.S.; Basu, N.K.; Banerjee, R. UDP-Glucuronosyltransferases: Gene Structures of UGT1 and UGT2 Families. Methods Enzymol. 2005, 400, 1–22, doi:10.1016/S0076-6879(05)00001-7.
218. Gamage, N.; Barnett, A.; Hempel, N.; Duggleby, R.G.; Windmill, K.F.; Martin, J.L.; McManus, M.E. Human Sulfotransferases and Their Role in Chemical Metabolism. Toxicol. Sci. 2006, 90, 5–22, doi:10.1093/toxsci/kfj061.
219. Blanchard, R.L.; Freimuth, R.R.; Buck, J.; Weinshilboum, R.M.; Coughtrie, M.W.H. A Proposed Nomenclature System for the Cytosolic Sulfotransferase (SULT) Superfamily. Pharmacogenetics 2004, 14, 199– 211, doi:10.1097/00008571-200403000-00009. 108
220. Falany, C.N. Molecular Enzymology of Human Liver Cytosolic Sulfotransferases. Trends Pharmacol. Sci. 1991, 12, 255–259.
221. Coughtrie, M.W.H. Function and Organization of the Human Cytosolic Sulfotransferase (SULT) Family. Chem. Biol. Interact. 2016, 259, 2–7, doi:10.1016/j.cbi.2016.05.005.
222. Suiko, M.; Kurogi, K.; Hashiguchi, T.; Sakakibara, Y.; Liu, M.C. Updated Perspectives on the Cytosolic Sulfotransferases (SULTs) and SULTMediated Sulfation. Biosci. Biotechnol. Biochem. 2017, 81, 63–72, doi:10.1080/09168451.2016.1222266.
223. Jancova, P.; Anzenbacher, P.; Anzenbacherova, E. Phase II Drug Metabolizing Enzymes. Biomed. Pap. 2010, 154, 103–116, doi:10.5507/bp.2010.017.
224. Oda, S.; Fukami, T.; Yokoi, T.; Nakajima, M. A Comprehensive Review of UDP-Glucuronosyltransferase and Esterases for Drug Development. Drug Metab. Pharmacokinet. 2015, 30, 30–51, doi:10.1016/j.dmpk.2014.12.001.
225. Almazroo, O.A.; Miah, M.K.; Venkataramanan, R. Drug Metabolism in the Liver. Clin. Liver Dis. 2017, 21, 1–20, doi:10.1016/j.cld.2016.08.001.
226. Kester, M.H.A.; Kaptein, E.; Roest, T.J.; Van Dijk, C.H.; Tibboel, D.; Meinl, W.; Glatt, H.; Coughtrie, M.W.H.; Visser, T.J. Characterization of Rat Iodothyronine Sulfotransferases. Am. J. Physiol. - Endocrinol. Metab. 2003, 285, E592–E598, doi:10.1152/ajpendo.00046.2003.
227. Tsoi, C.; Falany, C.N.; Morgenstern, R.; Swedmark, S. Molecular Cloning, Expression, and Characterization of a Canine Sulfotransferase That Is a Human ST1B2 Ortholog. Arch. Biochem. Biophys. 2001, 390, 87–92, doi:10.1006/abbi.2001.2373.
228. Shimada, M.; Terazawa, R.; Kamiyama, Y.; Honma, W.; Nagata, K.; Yamazoe, Y. Unique Properties of a Renal Sulfotransferase, St1d1, in Dopamine Metabolism. J. Pharmacol. Exp. Ther. 2004, 310, 808–814, doi:10.1124/jpet.104.065532.
229. Sakakibara, Y.; Yanagisawa, K.; Katafuchi, J.; Ringer, D.P.; Takami, Y.; Nakayama, T.; Suiko, M.; Liu, M.C. Molecular Cloning, Expression, and Characterization of Novel Human SULTIC Sulfotransferases That Catalyze the Sulfonation of N-Hydroxy-2- Acetylaminofluorene. J. Biol. Chem. 1998, 273, 33929–33935, doi:10.1074/jbc.273.51.33929. 109
230. Wilson, L.A.; Reyns, G.E.; Darras, V.M.; Coughtrie, M.W.H. CDNA Cloning, Functional Expression, and Characterization of Chicken Sulfotransferases Belonging to the SULT1B and SULT1C Families. Arch. Biochem. Biophys. 2004, 428, 64–72, doi:10.1016/j.abb.2004.05.008.
231. Tsoi, C.; Morgenstern, R.; Swedmark, S. Canine Sulfotransferase SULT1A1: Molecular Cloning, Expression, and Characterization. Arch. Biochem. Biophys. 2002, 401, 125–133, doi:10.1016/S0003- 9861(02)00021-8.
232. Liu, M.C.; Sakakibara, Y.; Liu, C.C. Bacterial Expression, Purification, and Characterization of a Novel Mouse Sulfotransferase That Catalyzes the Sulfation of Eicosanoids. Biochem. Biophys. Res. Commun. 1999, 254, 65–69, doi:10.1006/bbrc.1998.9872.
233. Teramoto, T.; Sakakibara, Y.; Inada, K.; Kurogi, K.; Liu, M.C.; Suiko, M.; Kimura, M.; Kakuta, Y. Crystal Structure of MSULT1D1, a Mouse Catecholamine Sulfotransferase. FEBS Lett. 2008, 582, 3909–3914, doi:10.1016/j.febslet.2008.10.035.
234. Böhmdorfer, M.; Szakmary, A.; Schiestl, R.; Vaquero, J.; Riha, J.; Brenner, S.; Thalhammer, T.; Szekeres, T.; Jäger, W. Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. Nutrients 2017, 9, 1347, doi:10.3390/nu9121347.
235. Omura, T.; Sato, R. The Carbon Monoxide-Bindng Pigent of Liver Microsomes. I. Evidence for Its Hemoprotein Nature. J. Biol. Chem. 1964, 239, 2370–2378.
236. Tsoi, C.; Falany, C.N.; Morgenstern, R.; Swedmark, S. Identification of a New Subfamily of Sulphotransferases: Cloning and Characterization of Canine SULT1D1. Biochem. J. 2001, 356, 891–897, doi:10.1042/0264- 6021:3560891.
237. Nowell, S.; Green, B.; Yong, M.T.; Wiese, R.; Kadlubar, F.F. Examination of Human Tissue Cytosols for Expression of Sulfotransferase Isoform 1A2 (SULT1A2) Using a SULT1A2-Specific Antibody. Mol. Pharmacol. 2005, 67, 394–399, doi:10.1124/mol.104.006171.
238. Riches, Z.; Stanley, E.L.; Bloomer, J.C.; Coughtrie, M.W.H. Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie.” Drug Metab. Dispos. 2009, 37, 2255–2261, doi:10.1124/dmd.109.028399. 110
239. Yamauchi, K.; Katsumata, S.; Ozaki, M. A Prototype of the Mammalian Sulfotransferase 1 (SULT1) Family in Xenopus Laevis: Molecular and Enzymatic Properties of XLSULT1B.S. Genes Genet. Syst. 2019, 94, 207–217, doi:10.1266/ggs.19-00026.
240. Tong, M.H.; Jiang, H.; Liu, P.; Lawson, J.A.; Brass, L.F.; Song, W.-C.C. Spontaneous Fetal Loss Caused by Placental Thrombosis in Estrogen Sulfotransferase-Deficient Mice. Nat. Med. 2005, 11, 153–159, doi:10.1038/nm1184.
241. Gershon, E.; Hourvitz, A.; Reikhav, S.; Maman, E.; Dekel, N. Low Expression of COX-2, Reduced Cumulus Expansion, and Impaired Ovulation in SULT1E1-Deficient Mice. FASEB J. 2007, 21, 1893–1901, doi:10.1096/FJ.06-7688COM.
242. Yi, M.; Negishi, M.; Lee, S.-J. Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives. J. Pers. Med. 2021, 11, 194, doi:10.3390/jpm11030194.
243. Paitz, R.T.; Bowden, R.M. Sulfonation of Maternal Steroids Is a Conserved Metabolic Pathway in Vertebrates. Integr. Comp. Biol. 2013, 53, 895–901, doi:10.1093/icb/ict027.
244. Paitz, R.T.; Angles, R.; Cagney, E. In Ovo Metabolism of Estradiol to Estrone Sulfate in Chicken Eggs: Implications for How Yolk Estradiol Influences Embryonic Development. Gen. Comp. Endocrinol. 2020, 287, 113320, doi:10.1016/j.ygcen.2019.113320.
245. Browne, P.; Conley, A.J.; Spraker, T.; Ream, R.R.; Lasley, B.L. Sex Steroid Concentrations and Localization of Steroidogenic Enzyme Expression in Free-Ranging Female Northern Fur Seals (Callorhinus Ursinus). Gen. Comp. Endocrinol. 2006, 147, 175–183, doi:10.1016/j.ygcen.2005.12.019.
246. Kodama, S.; Negishi, M. Sulfotransferase Genes: Regulation by Nuclear Receptors in Response to Xeno/Endo-Biotics. Drug Metab. Rev. 2013, 45, 441–449, doi:10.3109/03602532.2013.835630.
247. Allali-Hassani, A.; Pan, P.W.; Dombrovski, L.; Najmanovich, R.; Tempel, W.; Dong, A.; Loppnau, P.; Martin, F.; Thonton, J.; Edwards, A.M.; et al. Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases. PLOS Biol. 2007, 5, e97, doi:10.1371/JOURNAL.PBIO.0050097. 111
248. Stanley, E.L.; Hume, R.; Coughtrie, M.W.H. Expression Profiling of Human Fetal Cytosolic Sulfotransferases Involved in Steroid and Thyroid Hormone Metabolism and in Detoxification. Mol. Cell. Endocrinol. 2005, 240, 32–42, doi:10.1016/j.mce.2005.06.003.
249. Kurogi, K.; Shimohira, T.; Kouriki-Nagatomo, H.; Zhang, G.; Miller, E.R.; Sakakibara, Y.; Suiko, M.; Liu, M.C. Human Cytosolic Sulphotransferase SULT1C3: Genomic Analysis and Functional Characterization of Splice Variant SULT1C3a and SULT1C3d. J. Biochem. 2017, 162, 403–414, doi:10.1093/jb/mvx044.
250. Meinl, W.; Donath, C.; Schneider, H.; Sommer, Y.; Glatt, H. SULT1C3, an Orphan Sequence of the Human Genome, Encodes an Enzyme Activating Various Promutagens. Food Chem. Toxicol. 2008, 46, 1249– 1256, doi:10.1016/j.fct.2007.08.040.
251. Runge-Morris, M.; Kocarek, T.A. Expression of the Sulfotransferase 1C Family: Implications for Xenobiotic Toxicity. Drug Metab. Rev. 2013, 45, 450–459, doi:10.3109/03602532.2013.835634.
252. Nagata, K.; Ozawa, S.; Miyata, M.; Shimada, M.; Gong, D.W.; Yamazoe, Y.; Kato, R. Isolation and Expression of a CDNA Encoding a MaleSpecific Rat Sulfotransferase That Catalyzes Activation of N-Hydroxy-2- Acetylaminofluorene. J. Biol. Chem. 1993, 268, 24720–24725, doi:10.1016/s0021-9258(19)74524-4.
253. Lu, H.; Gunewardena, S.; Cui, J.Y.; Yoo, B.; Zhong, X.B.; Klaassen, C.D. RNA-Sequencing Quantification of Hepatic Ontogeny and Tissue Distribution of MRNAs of Phase II Enzymes in Mice. Drug Metab. Dispos. 2013, 41, 844–857, doi:10.1124/dmd.112.050211.
254. Kurogi, K.; Sakakibara, Y.; Yasuda, S.; Liu, M.-C.; Suiko, M. Molecular Cloning and Characterization of a Novel Canine Sulfotransferase. Anim. Cell Technol. Basic Appl. Asp. 2010, 16, 221–229, doi:10.1007/978-90- 481-3892-0_36.
255. Saengtienchai, A.; Ikenaka, Y.; Nakayama, S.M.M.; Mizukawa, H.; Kakehi, M.; Bortey-Sam, N.; Darwish, W.S.; Tsubota, T.; Terasaki, M.; Poapolathep, A.; et al. Identification of Interspecific Differences in Phase II Reactions: Determination of Metabolites in the Urine of 16 Mammalian Species Exposed to Environmental Pyrene. Environ. Toxicol. Chem. 2014, 33, 2062–2069, doi:10.1002/etc.2656. 112
256. Wu, B.; Basu, S.; Meng, S.; Wang, X.; Zhang, S.; Hu, M. Regioselective Sulfation and Glucuronidation of Phenolics: Insights into the Structural Basis of Conjugation. Curr. Drug Metab. 2011, 12, 900.
257. Grimm, F.A.; Lehmler, H.-J.; Koh, W.X.; DeWall, J.; Teesch, L.M.; Hornbuckle, K.C.; Thorne, P.S.; Robertson, L.W.; Duffel, M.W. Identification of a Sulfate Metabolite of PCB 11 in Human Serum. Environ. Int. 2017, 98, 120–128, doi:10.1016/j.envint.2016.10.023.
258. Suiko, M.; Sakakibara, Y.; Liu, M.Y.; Yang, Y.S.; Liu, M.C. Cytosolic Sulfotransferases and Environmental Estrogenic Chemicals. J. Pestic. Sci. 2005, 30, 345–353, doi:10.1584/jpestics.30.345.
259. Hohenlohe, P.A.; Funk, W.C.; Rajora, O.P. Population Genomics for Wildlife Conservation and Management. Mol. Ecol. 2021, 30, 62–82, doi:10.1111/MEC.15720.
260. Zhou, X.; Guang, X.; Sun, D.; Xu, S.; Li, M.; Seim, I.; Jie, W.; Yang, L.; Zhu, Q.; Xu, J.; et al. Population Genomics of Finless Porpoises Reveal an Incipient Cetacean Species Adapted to Freshwater. Nat. Commun. 2018, 9, 1–8, doi:10.1038/s41467-018-03722-x.
261. Wright, B.; Farquharson, K.A.; McLennan, E.A.; Belov, K.; Hogg, C.J.; Grueber, C.E. From Reference Genomes to Population Genomics: Comparing Three Reference-Aligned Reduced-Representation Sequencing Pipelines in Two Wildlife Species. BMC Genomics 2019, 20, 1–10, doi:10.1186/S12864-019-5806-Y/TABLES/3.
262. Pellock, S.J.; Redinbo, M.R. Glucuronides in the Gut: Sugar-Driven Symbioses between Microbe and Host. J. Biol. Chem. 2017, 292, 8569– 8576, doi:10.1074/jbc.R116.767434.
263. Collins, S.L.; Patterson, A.D. The Gut Microbiome: An Orchestrator of Xenobiotic Metabolism. Acta Pharm. Sin. B 2020, 10, 19–32, doi:10.1016/J.APSB.2019.12.001.
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