Kanzaki, H., Chiba, M., Shimizu, Y., and Mitani, H. (2001). Dual regulation of
osteoclast differentiation by periodontal ligament cells through RANKL stimulation
and OPG inhibition. J. Dent. Res. 80 (3), 887–891. doi:10.1177/
00220345010800030801
Andrukhov, O., Hong, J. S., Andrukhova, O., Blufstein, A., Moritz, A., and
Rausch-Fan, X. (2017). Response of human periodontal ligament stem cells to IFNγ and TLR-agonists. Sci. Rep. 7 (1), 12856. doi:10.1038/s41598-017-12480-7
Brewer, J. W., Hendershot, L. M., Sherr, C. J., and Diehl, J. A. (1999). Mammalian
unfolded protein response inhibits cyclin D1 translation and cell-cycle progression.
Proc. Natl. Acad. Sci. U. S. A. 96 (15), 8505–8510. doi:10.1073/pnas.96.15.8505
Katsuda, T., and Ochiya, T. (2015). Molecular signatures of mesenchymal stem
cell-derived extracellular vesicle-mediated tissue repair. Stem Cell Res. Ther. 6, 212.
doi:10.1186/s13287-015-0214-y
Chen, B., Wu, W., Sun, W., Zhang, Q., Yan, F., and Xiao, Y. (2014). RANKL
expression in periodontal disease: Where does RANKL come from? Biomed. Res.
Int. 2014, 731039. doi:10.1155/2014/731039
Kim, D., Lee, A. E., Xu, Q., Zhang, Q., and Le, A. D. (2021). Gingiva-derived
mesenchymal stem cells: Potential application in tissue engineering and
regenerative medicine - a comprehensive review. Front. Immunol. 12, 667221.
doi:10.3389/fimmu.2021.667221
Collison, J. (2018). Bone: ER stress causes osteoclastogenesis. Nat. Rev.
Rheumatol. 14 (4), 184. doi:10.1038/nrrheum.2018.24
Kim, M. S., Day, C. J., Selinger, C. I., Magno, C. L., Stephens, S. R., and Morrison,
N. A. (2006). MCP-1-induced human osteoclast-like cells are tartrate-resistant acid
phosphatase, NFATc1, and calcitonin receptor-positive but require receptor
activator of NFkappaB ligand for bone resorption. J. Biol. Chem. 281 (2),
1274–1285. doi:10.1074/jbc.M510156200
El Moshy, S., Radwan, I. A., Rady, D., Abbass, M. M. S., El-Rashidy, A. A., Sadek,
K. M., et al. (2020). Dental stem cell-derived secretome/conditioned medium: The
future for regenerative therapeutic applications. Stem Cells Int. 2020, 7593402.
doi:10.1155/2020/7593402
Fukuda, T., Sanui, T., Toyoda, K., Tanaka, U., Taketomi, T., Uchiumi, T., et al.
(2013). Identification of novel amelogenin-binding proteins by proteomics analysis.
PLoS One 8 (10), e78129. doi:10.1371/journal.pone.0078129
Kou, X., Xu, X., Chen, C., Sanmillan, M. L., Cai, T., Zhou, Y., et al. (2018). The
Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to
accelerate wound healing. Sci. Transl. Med. 10 (432), eaai8524. doi:10.1126/
scitranslmed.aai8524
Garg, A. D., Kaczmarek, A., Krysko, O., Vandenabeele, P., Krysko, D. V., and
Agostinis, P. (2012). ER stress-induced inflammation: Does it aid or impede disease
progression? Trends Mol. Med. 18 (10), 589–598. doi:10.1016/j.molmed.2012.
06.010
Kukita, T., Wada, N., Kukita, A., Kakimoto, T., Sandra, F., Toh, K., et al. (2004).
RANKL-induced DC-STAMP is essential for osteoclastogenesis. J. Exp. Med. 200
(7), 941–946. doi:10.1084/jem.20040518
Hajishengallis, G. (2015). Periodontitis: From microbial immune subversion to
systemic inflammation. Nat. Rev. Immunol. 15 (1), 30–44. doi:10.1038/nri3785
Li, B., Ouchi, T., Cao, Y., Zhao, Z., and Men, Y. (2021). Dental-derived
mesenchymal stem cells: State of the art. Front. Cell Dev. Biol. 9, 654559. doi:10.
3389/fcell.2021.654559
Hetz, C., Zhang, K., and Kaufman, R. J. (2020). Mechanisms, regulation and
functions of the unfolded protein response. Nat. Rev. Mol. Cell Biol. 21 (8), 421–438.
doi:10.1038/s41580-020-0250-z
Luo, X. H., Guo, L. J., Xie, H., Yuan, L. Q., Wu, X. P., Zhou, H. D., et al. (2006).
Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts
through the MAPK signaling pathway. J. Bone Min. Res. 21 (10), 1648–1656. doi:10.
1359/jbmr.060707
Hien, L. T., and Back, S. H. (2021). Establishment of a reporter system for
monitoring activation of the ER stress transducer ATF6β. Biochem. Biophys. Res.
Commun. 558, 1–7. doi:10.1016/j.bbrc.2021.04.052
Jiang, M., Li, Z., and Zhu, G. (2022). The role of endoplasmic reticulum stress in
the pathophysiology of periodontal disease. J. Periodontal Res. 57 (5), 915–932.
doi:10.1111/jre.13031
Nakanishi, K., Sudo, T., and Morishima, N. (2005). Endoplasmic
reticulum stress signaling transmitted by ATF6 mediates apoptosis
during muscle development. J. Cell Biol. 169 (4), 555–560. doi:10.1083/
jcb.200412024
Kajiya, M., and Kurihara, H. (2021). Molecular mechanisms of periodontal
disease. Int. J. Mol. Sci. 22 (2), 930. doi:10.3390/ijms22020930
Nakao, Y., Fukuda, T., Zhang, Q., Sanui, T., Shinjo, T., Kou, X., et al. (2021).
Exosomes from TNF-α-treated human gingiva-derived MSCs enhance
Frontiers in Cell and Developmental Biology
16
frontiersin.org
Hayashi et al.
10.3389/fcell.2022.1061216
Stoecklin-Wasmer, C., Guarnieri, P., Celenti, R., Demmer, R. T., Kebschull, M.,
and Papapanou, P. N. (2012). MicroRNAs and their target genes in gingival tissues.
J. Dent. Res. 91 (10), 934–940. doi:10.1177/0022034512456551
M2 macrophage polarization and inhibit periodontal bone loss. Acta Biomater. 122,
306–324. doi:10.1016/j.actbio.2020.12.046
Nezami, B. G., Mwangi, S. M., Lee, J. E., Jeppsson, S., Anitha, M., Yarandi, S. S.,
et al. (2014). MicroRNA 375 mediates palmitate-induced enteric neuronal damage
and high-fat diet-induced delayed intestinal transit in mice. Gastroenterology 146
(2), 473–483. doi:10.1053/j.gastro.2013.10.053
Thuerauf, D. J., Marcinko, M., Belmont, P. J., and Glembotski, C. C. (2007).
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on
endoplasmic reticulum stress response gene expression and cell viability. J. Biol.
Chem. 282 (31), 22865–22878. doi:10.1074/jbc.M701213200
Orsini, G., Pagella, P., and Mitsiadis, T. A. (2018). Modern trends in dental
medicine: An update for internists. Am. J. Med. 131 (12), 1425–1430. doi:10.1016/j.
amjmed.2018.05.042
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., and Lötvall, J. O. (2007).
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic
exchange between cells. Nat. Cell Biol. 9 (6), 654–659. doi:10.1038/ncb1596
Park, W. S., Ahn, S. Y., Sung, S. I., Ahn, J. Y., and Chang, Y. S. (2018).
Strategies to enhance paracrine potency of transplanted mesenchymal stem
cells in intractable neonatal disorders. Pediatr. Res. 83 (1-2), 214–222. doi:10.
1038/pr.2017.249
Watanabe, T., Kukita, T., Kukita, A., Wada, N., Toh, K., Nagata, K., et al. (2004).
Direct stimulation of osteoclastogenesis by MIP-1alpha: Evidence obtained from
studies using RAW264 cell clone highly responsive to RANKL. J. Endocrinol. 180
(1), 193–201. doi:10.1677/joe.0.1800193
Pethő, A., Chen, Y., and George, A. (2018). Exosomes in extracellular matrix
bone Biology. Curr. Osteoporos. Rep. 16 (1), 58–64. doi:10.1007/s11914-0180419-y
Watanabe, Y., Fukuda, T., Hayashi, C., Nakao, Y., Toyoda, M., Kawakami, K.,
et al. (2022). Extracellular vesicles derived from GMSCs stimulated with TNF-α and
IFN-α promote M2 macrophage polarization via enhanced CD73 and CD5L
expression. Sci. Rep. 12 (1), 13344. doi:10.1038/s41598-022-17692-0
Piper, K., Boyde, A., and Jones, S. J. (1992). The relationship between the number
of nuclei of an osteoclast and its resorptive capability in vitro. Anat. Embryol. 186
(4), 291–299. doi:10.1007/bf00185977
Xia, Y., Wei, K., Hu, L. Q., Zhou, C. R., Lu, Z. B., Zhan, G. S., et al. (2020).
Exosome-mediated transfer of miR-1260b promotes cell invasion through Wnt/βcatenin signaling pathway in lung adenocarcinoma. J. Cell. Physiol. 235, 6843–6853.
doi:10.1002/jcp.29578
Quesenberry, P. J., Aliotta, J., Deregibus, M. C., and Camussi, G. (2015). Role of
extracellular RNA-carrying vesicles in cell differentiation and reprogramming. Stem
Cell Res. Ther. 6, 153. doi:10.1186/s13287-015-0150-x
Xiang, L., Chen, M., He, L., Cai, B., Du, Y., Zhang, X., et al. (2014). Wnt5a
regulates dental follicle stem/progenitor cells of the periodontium. Stem Cell Res.
Ther. 5 (6), 135. doi:10.1186/scrt525
Raposo, G., and Stoorvogel, W. (2013). Extracellular vesicles: Exosomes,
microvesicles, and friends. J. Cell Biol. 200 (4), 373–383. doi:10.1083/jcb.
201211138
Seong, M., and Kang, H. (2020). Hypoxia-induced miR-1260b regulates vascular
smooth muscle cell proliferation by targeting GDF11. BMB Rep. 53 (4), 206–211.
doi:10.5483/BMBRep.2020.53.4.136
Xiong, Y., Chen, H., Lin, P., Wang, A., Wang, L., and Jin, Y. (2017).
ATF6 knockdown decreases apoptosis, arrests the S phase of the cell cycle, and
increases steroid hormone production in mouse granulosa cells. Am. J. Physiol. Cell
Physiol. 312 (3), C341–C353. doi:10.1152/ajpcell.00222.2016
Shen, J., Chen, X., Hendershot, L., and Prywes, R. (2002). ER stress regulation
of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of
Golgi localization signals. Dev. Cell 3 (1), 99–111. doi:10.1016/s1534-5807(02)
00203-4
Yamada, H., Nakajima, T., Domon, H., Honda, T., and Yamazaki, K. (2015).
Endoplasmic reticulum stress response and bone loss in experimental periodontitis
in mice. J. Periodontal Res. 50 (4), 500–508. doi:10.1111/jre.12232
Stengel, S. T., Fazio, A., Lipinski, S., Jahn, M. T., Aden, K., Ito, G., et al. (2020).
Activating transcription factor 6 mediates inflammatory signals in intestinal
epithelial cells upon endoplasmic reticulum stress. Gastroenterology 159 (4),
1357–1374. e1310. doi:10.1053/j.gastro.2020.06.088
Zhang, Q., Nguyen, P., Xu, Q., Park, W., Lee, S., Furuhashi, A., et al. (2017).
Neural progenitor-like cells induced from human gingiva-derived mesenchymal
stem cells regulate myelination of schwann cells in rat sciatic nerve regeneration.
Stem Cells Transl. Med. 6 (2), 458–470. doi:10.5966/sctm.2016-0177
Frontiers in Cell and Developmental Biology
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