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19）
11保健所管内の居住者を対象とした大規模コホートで
１． 厚生労働省：平成30年 国民健康・栄養調査
https://www.mhlw.go.jp/stf/newpage_08789.html
あり山形県民は含まれていない。山形県一般住民にお
ける睡眠時間と死亡リスクの関連を明らかにした本研
究の意義は大きく、今後はがん種別の死亡リスクの検
討も必要であると考えている。
本研究の強みは、日本人の一般集団を対象としたこ
と、統計解析が性別、高血圧、糖尿病、喫煙、飲酒、
BMIなどの多因子で調整されていることである。一方
（21/3/11）
２． OECD. Society at a Glance 2019: OECD Social
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https://www.mhlw.go.jp/stf/newpage_14156.html
で、本研究のいくつかの限界も考慮しなければならな
い。第１にフォローアップ期間が短く、イベント数が
少ないこと、第２に本研究では不眠症の診断や睡眠薬
（21/3/11）
５．
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Yamagata Med J（ISSN 0288-030X）2021；39
村上，今田，小杉，渡辺，石澤，山下，上野，嘉山，櫻田
（2）
：102-109
DOI 10.15022/00005043
Association of sleep duration with all-cause mortality and
cancer mortality in the elderly people:
Findings from the Yamagata Cohort study
Narumi Murakami＊，＊＊＊, Tsuneo Konta＊＊, Naoko Kosugi＊＊＊, Masafumi Watanabe＊＊＊＊,
Kenichi Ishizawa＊＊＊＊, Hidetoshi Yamashita＊＊＊＊, Yoshiyuki Ueno＊＊＊＊,
Takamasa Kayama＊＊＊＊, Kaori Sakurada＊＊＊＊＊
Yamagata University Faculty of Medicine, Graduate School of Nursing
＊＊
Department of Public Health, Yamagata University Faculty of Medicine
＊＊＊
Division of Nursing, Yamagata University Hospital
＊＊＊＊
Institute of Medical Science, Yamagata University Faculty of Medicine
＊＊＊＊＊
Department of Fundamental Nursing, Yamagata University Faculty of Medicine. School of Nursing
ABSTRACT
Background: According to the National Health and Nutrition Survey conducted in 2019, more than
30% of both men and women aged 70 and over answered that they "had trouble waking up in the
middle of the night" or "felt sleepy during the day" at least three times a week during the past month.
It is an important issue to clarify the relationship between sleep and health of the elderly in our
super-aged society. The purpose of this study was to clarify the relationship between sleep duration
and life prognosis in elderly people aged 65 and over.
Materials and Methods: A total of 10,155 residents aged 65 years or older from 7 cities in Yamagata
Prefecture who provided consent to participate in the Yamagata Cohort Study from 2009 to 2019
were included in the study. They were classified into three groups according to sleep duration: ≤6
hours, 6－7.9 hours, and ≥8 hours per day. The 6－7.9-hour group was the control group, and the
association with all-cause mortality and cancer mortality was examined in a Cox proportional hazards
model.
Results: During follow-up（median, 7.0 years）,362 subjects died, of which 118 died from cancer. Long
sleep duration was associated with increased all-cause mortality in elderly women（hazard ratio [HR]
1.60, 95% confidence interval [CI]: 1.00-2.52）, and both short and long sleep durations were associated
with increased cancer-mortality in elderly women
（HR 3.32, 95%CI: 1.05-9.00; HR 2.44, 95%CI: 1.08-5.51）
Conclusion: In this study, elderly women had a high risk of death with long sleep durations of 8
hours or more, and they also had a high risk of cancer death with short sleep durations of less than 6
hours and long sleep durations of 8 hours or more.
Keywords: sleep duration, all-cause mortality, cancer mortality, elderly
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