リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

大学・研究所にある論文を検索できる 「Auditory-Cognitive training improves brain plasticity and cognitive function in the healthy older adults」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

コピーが完了しました

URLをコピーしました

論文の公開元へ論文の公開元へ
書き出し

Auditory-Cognitive training improves brain plasticity and cognitive function in the healthy older adults

河田 百合子 東北大学

2021.09.24

概要

The number of older adults is increasing globally. Aging is associated with cognitive and sensory decline. Age-related hearing loss causes speech perception problems and has been linked to cognitive decline. Additionally, declined auditory performance and cognitive function affect the quality of life of older adults. Therefore, it is important to develop an intervention method to improve both auditory and cognitive performances. A previous study reported that a combination of auditory and cognitive (AC) training is more beneficial than a single auditory or cognitive training; however, the study did not directly measure auditory abilities using objective measures, such as the pure-tone audiometry (PTA) threshold. In addition, a suitable active control group was not included in the study. The current study aimed to investigate the beneficial effects of AC training on auditory ability and cognitive functions in healthy older adults. Considering the unresolved issues of the previous study, I focused on the following points in this study: 1) objective auditory measures, such as PTA, were used, 2) an active control group was included a randomize controlled study, and 3) sound volume was manipulated for auditory factor difficulty during training. Fifty healthy older adults were randomly divided into four training groups—an AC training group, an auditory training group (A training), a cognitive training group (C training), and an active control group. Cognitive function measures (digit-cancellation test [D-CAT]; logical memory [LM]; digit span), auditory measures (PTA), and magnetic resonance imaging (MRI) measures were evaluated before and after the training periods. I did not find any statistically significant beneficial effects of AC training on cognitive and auditory performance compared to that of other training modalities (A training group, C training group, and active control group). Compared to other groups, the AC training group showed differences in regional gray matter volume (rGMV) in the right dorsolateral prefrontal cortex, the left inferior temporal gyrus (L. ITG), the left superior frontal gyrus, the left orbitofrontal cortex, the right cerebellum (lobule 7 Crus 1).

According to PTA findings, the auditory training factor groups (ATFGs, the AC and A training groups) improved in auditory measures compared to the non-ATFGs (the C training group and active control group). The ATFGs showed an increase in rGMV and FC in the left temporal pole compared to the non-ATFGs. The cognitive training factor groups (CTFGs; the AC and C training groups) showed statistically significant improvement in cognitive performances in terms of LM and D-CAT results compared to the non-CTFGs (A training group and active control group). AC training significantly changed rGMV in brain regions related to attention and memory. These results suggest that older adults can listen to sound with low volume after auditory training (ATFGs), and cognitive training (CTFGs) improved their attention and episodic memory performance. In addition, AC training led to changes in brain structure related to cognitive and auditory processes. Therefore, the present study newly developed AC training would be useful in enhancing the quality of life of older adults.

参考文献

Amano, S., Kondo, T., & Kakehi, K. (1995). Modality dependency of familiarity ratings of Japanese words. Percept Psychophys, 57(5), 598-603. https://doi.org/10.3758/bf03213265

Auffray, C., & Juhel, J. (2001). General and differential effects of a multimodal cognitive training program for the eldenly. Annee Psychologique, 101.

Baltes, P. B., & Lindenberger, U. (1997). Emergence of a powerful connection between sensory and cognitive functions across the adult life span: a new window to the study of cognitive aging? Psychol Aging, 12(1), 12-21. https://doi.org/10.1037//0882-7974.12.1.12

Biel, D., Steiger, T., Volkmann, T., Jochems, N., & Bunzeck, N. (2020). The gains of a 4‐week cognitive training are not modulated by novelty. Human Brain Mapping, 41. https://doi.org/10.1002/hbm.24965

Cohen, L., Dehaene, S., Naccache, L., Lehericy, S., Dehaene-Lambertz, G., Henaff, M. A., & Michel, F. (2000). The visual word form area: spatial and temporal characterization of an initial stage of reading in normal subjects and posterior split-brain patients. Brain, 123 ( Pt 2), 291-307. https://doi.org/10.1093/brain/123.2.291

Cohen, L., Jobert, A., Le Bihan, D., & Dehaene, S. (2004). Distinct unimodal and multimodal regions for word processing in the left temporal cortex. Neuroimage, 23(4), 1256-70. https://doi.org/10.1016/j.neuroimage.2004.07.052

Dalton, D. S., Cruickshanks, K. J., Klein, B. E. K., Klein, R., Wiley, T. L., & Nondahl, D. M. (2003). The impact of hearing loss on quality of life in older adults. The Gerontologist, 43(5), 661-68. https://doi.org/10.1093/geront/43.5.661

Deal, J. A., Betz, J., Yaffe, K., Harris, T., Purchase-Helzner, E., Satterfield, S., Pratt, S., Govil, N., Simonsick, E. M., Lin, F. R., & Health, A. B. C. S. G. (2017). Hearing impairment and incident dementia and cognitive decline in older adults: the health ABC study. J Gerontol A Biol Sci Med Sci, 72(5), 703-09. https://doi.org/10.1093/gerona/glw069

Duncan, J. (2010). The multiple-demand (MD) system of the primate brain: mental programs for intelligent behaviour. Trends Cogn Sci, 14(4), 172-9. https://doi.org/10.1016/j.tics.2010.01.004

Fiebach, C. J., Rissman, J., & D'Esposito, M. (2006). Modulation of inferotemporal cortex activation during verbal working memory maintenance. Neuron, 51(2), 251-61. https://doi.org/10.1016/j.neuron.2006.06.007

Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). "Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res, 12(3), 189-98. https://doi.org/10.1016/0022-3956(75)90026-6

Furuyashiki, T., & Gallagher, M. (2007). Neural encoding in the orbitofrontal cortex related to goal-directed behavior. Ann N Y Acad Sci, 1121, 193-215. https://doi.org/10.1196/annals.1401.037

Golino, M. T. S., Flores Mendoza, C., & Golino, H. F. (2017). Effects of cognitive training on cognitive performance of healthy older adults. Span J Psychol, 20, E39. https://doi.org/10.1017/sjp.2017.38

Hajime, S. (1994). A consideration of self-assessment for hearing handicap. Audiology Japan, 37, 395-6. https://doi.org/10.4295/audiology.37.395

Hatta, T., Ito, Y., & Yoshizaki, K. (2000). D-CAT manual (Screening test for attention). Osaka.: Union Press.

Herbster, A. N., Mintun, M. A., Nebes, R. D., & Becker, J. T. (1997). Regional cerebral blood flow during word and nonword reading. Hum Brain Mapp, 5(2), 84-92. https://doi.org/10.1002/(sici)1097-0193(1997)5:2<84::aid-hbm2>3.0.co;2-i

Hertrich, I., Dietrich, S., Blum, C., & Ackermann, H. (2021). The Role of the Dorsolateral Prefrontal Cortex for Speech and Language Processing. Front Hum Neurosci, 15, 645209. https://doi.org/10.3389/fnhum.2021.645209

Holm, S. (1979). A simple sequentially rejective multiple test procedure. Scand. J. Stat, 6(2), 65-70.

Holtzer, R., Schoen, C., Demetriou, E., Mahoney, J. R., Izzetoglu, M., Wang, C., & Verghese, J. (2017). Stress and gender effects on prefrontal cortex oxygenation levels assessed during single and dual-task walking conditions. The European journal of neuroscience, 45(5), 660-70. https://doi.org/10.1111/ejn.13518

Huang, Y., Huang, Q., Chen, X., Wu, X., & Li, L. (2009). Transient auditory storage of acoustic details is associated with release of speech from informational masking in reverberant conditions. J Exp Psychol Hum Percept Perform, 35(5), 1618-28. https://doi.org/10.1037/a0015791

Jayakody, D. M. P., Friedland, P. L., Martins, R. N., & Sohrabi, H. R. (2018). Impact of Aging on the Auditory System and Related Cognitive Functions: A Narrative Review. Front Neurosci, 12, 125. https://doi.org/10.3389/fnins.2018.00125

Karawani, H., Bitan, T., Attias, J., & Banai, K. (2016). Auditory perceptual learning in adults with and without age-related hearing loss [10.3389/fpsyg.2015.02066]. Frontiers in Psychology, 6, 2066. https://www.frontiersin.org/article/10.3389/fpsyg.2015.02066

Khalfa, S., Bougeard, R., Morand, N., Veuillet, E., Isnard, J., Guenot, M., Ryvlin, P., Fischer, C., & Collet, L. (2001). Evidence of peripheral auditory activity modulation by the auditory cortex in humans. Neuroscience, 104(2), 347-58. https://doi.org/https://doi.org/10.1016/S0306-4522(01)00072-0

Kulason, K., Nouchi, R., Hoshikawa, Y., Noda, M., Okada, Y., & Kawashima, R. (2018). The beneficial effects of cognitive training with simple calculation and reading aloud (SCRA) in the elderly postoperative population: a pilot randomized controlled trial. Front Aging Neurosci, 10, 68. https://doi.org/10.3389/fnagi.2018.00068

Levitt, H., Oden, C., Simon, H., Noack, C., & Lotze, A. (2011). Entertainment overcomes barriers of auditory training. The Hearing Journal, 64(8), 40,42. https://doi.org/10.1097/01.HJ.0000403510.80465.7b

Li, C. M., Zhang, X., Hoffman, H. J., Cotch, M. F., Themann, C. L., & Wilson, M. R. (2014). Hearing impairment associated with depression in US adults, National Health and Nutrition Examination Survey 2005-2010. JAMA Otolaryngol Head Neck Surg, 140(4), 293-302. https://doi.org/10.1001/jamaoto.2014.42

Li, H., Kong, L., Wu, X., & Li, L. (2013). Primitive auditory memory is correlated with spatial unmasking that is based on direct-reflection integration. PLoS One, 8(4), e63106. https://doi.org/10.1371/journal.pone.0063106

Lin, F. R. (2011). Hearing loss and cognition among older adults in the United States. J Gerontol A Biol Sci Med Sci, 66(10), 1131-6. https://doi.org/10.1093/gerona/glr115

Lin, F. R., Yaffe, K., Xia, J., Xue, Q. L., Harris, T. B., Purchase-Helzner, E., Satterfield, S., Ayonayon, H. N., Ferrucci, L., Simonsick, E. M., & Health, A. B. C. S. G. (2013). Hearing loss and cognitive decline in older adults. JAMA Intern Med, 173(4), 293-9. https://doi.org/10.1001/jamainternmed.2013.1868

Lin, Y. H., Young, I. M., Conner, A. K., Glenn, C. A., Chakraborty, A. R., Nix, C. E., Bai, M. Y., Dhanaraj, V., Fonseka, R. D., Hormovas, J., Tanglay, O., Briggs, R. G., & Sughrue, M. E. (2020). Anatomy and White Matter Connections of the Inferior Temporal Gyrus. World Neurosurg, 143, e656-e66. https://doi.org/10.1016/j.wneu.2020.08.058

Massaro, D. W. (1972). Preperceptual images, processing time, and perceptual units in auditory perception. Psychol Rev, 79(2), 124-45. https://doi.org/10.1037/h0032264

Matthaus, F., Schmidt, J. P., Banerjee, A., Schulze, T. G., Demirakca, T., & Diener, C. (2012). Effects of age on the structure of functional connectivity networks during episodic and working memory demand. Brain Connect, 2(3), 113-24. https://doi.org/10.1089/brain.2012.0077

May, A. E., Upfold, L. J., & Battaglia, J. A. (1990). The advantages and disadvantages of ITC, ITE and BTE hearing aids: Diary and interview reports from elderly users. British Journal of Audiology, 24(5), 301-09. https://doi.org/10.3109/03005369009076570

Mick, P., Kawachi, I., & Lin, F. R. (2014). The association between hearing loss and social isolation in older adults. Otolaryngology–Head and Neck Surgery, 150(3), 378-84. https://doi.org/10.1177/0194599813518021

Musiek, F. E., Chermak, G. D., & Weihing, J. (2014). Auditory training. In Handbook of central auditory processing disorder: Comprehensive intervention, Volume II, 2nd ed. (pp. 157-200). Plural Publishing Inc. Niendam, T. A., Laird, A. R., Ray, K. L., Dean, Y. M., Glahn, D. C., & Carter, C. S. (2012).

Meta-analytic evidence for a superordinate cognitive control network subserving diverse executive functions. Cogn Affect Behav Neurosci, 12(2), 241-68. https://doi.org/10.3758/s13415-011-0083-5

Nijboer, M., Borst, J., van Rijn, H., & Taatgen, N. (2014). Single-task fMRI overlap predicts concurrent multitasking interference. Neuroimage, 100, 60-74. https://doi.org/10.1016/j.neuroimage.2014.05.082

Nissim, N. R., O'Shea, A. M., Bryant, V., Porges, E. C., Cohen, R., & Woods, A. J. (2017). Frontal structural neural correlates of working memory performance in older adults. Frontiers in aging neuroscience, 8, 328-28. https://doi.org/10.3389/fnagi.2016.00328

Nogueira, R., Abolafia, J. M., Drugowitsch, J., Balaguer-Ballester, E., Sanchez-Vives, M. V., & Moreno-Bote, R. (2017). Lateral orbitofrontal cortex anticipates choices and integrates prior with current information. Nature Communications, 8(1), 14823. https://doi.org/10.1038/ncomms14823

Nouchi, R., Saito, T., Nouchi, H., & Kawashima, R. (2016). Small acute benefits of 4 weeks processing speed training games on processing speed and inhibition performance and depressive mood in the healthy elderly people: evidence from a randomized control trial. Front Aging Neurosci, 8, 302. https://doi.org/10.3389/fnagi.2016.00302

Nouchi, R., Taki, Y., Takeuchi, H., Hashizume, H., Akitsuki, Y., Shigemune, Y., Sekiguchi, A., Kotozaki, Y., Tsukiura, T., Yomogida, Y., & Kawashima, R. (2012a). Brain training game improves executive functions and processing speed in the elderly: a randomized controlled trial. PLoS One, 7(1), e29676. https://doi.org/10.1371/journal.pone.0029676

Nouchi, R., Taki, Y., Takeuchi, H., Hashizume, H., Nozawa, T., Sekiguchi, A., Nouchi, H., & Kawashima, R. (2012b). Beneficial effects of short-term combination exercise training on diverse cognitive functions in healthy older people: study protocol for a randomized controlled trial. Trials, 13, 200. https://doi.org/10.1186/1745-6215-13-200

Nouchi, R., Taki, Y., Takeuchi, H., Sekiguchi, A., Hashizume, H., Nozawa, T., Nouchi, H., & Kawashima, R. (2014). Four weeks of combination exercise training improved executive functions, episodic memory, and processing speed in healthy elderly people: evidence from a randomized controlled trial. Age (Dordr), 36(2), 787-99. https://doi.org/10.1007/s11357-013-9588-x

Ohlemiller, K. K. (2004). Age-related hearing loss: the status of Schuknecht's typology. Curr Opin Otolaryngol Head Neck Surg, 12(5), 439-43. https://doi.org/10.1097/01.moo.0000134450.99615.22

Ohlenforst, B., Zekveld, A. A., Jansma, E. P., Wang, Y., Naylor, G., Lorens, A., Lunner, T., & Kramer, S. E. (2017). Effects of Hearing Impairment and Hearing Aid Amplification on Listening Effort: A Systematic Review. Ear Hear, 38(3), 267-81. https://doi.org/10.1097/AUD.0000000000000396

Olson, A. D. (2015). Options for Auditory Training for Adults with Hearing Loss. Semin Hear, 36(4), 284-95. https://doi.org/10.1055/s-0035-1564461

Olson, I. R., Plotzker, A., & Ezzyat, Y. (2007). The Enigmatic temporal pole: a review of findings on social and emotional processing. Brain, 130(7), 1718-31. https://doi.org/10.1093/brain/awm052

Ouda, L., Profant, O., & Syka, J. (2015). Age-related changes in the central auditory system. Cell Tissue Res, 361(1), 337-58. https://doi.org/10.1007/s00441-014-2107-2

Palmer, C. V., Mulla, R., Dervin, E., & Coyan, K. C. (2017). HearCARE: Hearing and Communication Assistance for Resident Engagement. Semin Hear, 38(2), 184-97. https://doi.org/10.1055/s-0037-1601574

Peelle, J. E. (2019). The neural basis for auditory and audiovisual speech perception. In The Routledge Handbook of Phonetics. https://doi.org/10.31234/osf.io/39ej7

Pekrun, R., Götz, T., Daniels, L., Stupnisky, R., & Perry, R. (2010). Boredom in Achievement Settings: Exploring Control-Value Antecedents and Performance Outcomes of a Neglected Emotion. First publ. in: Journal of Educational Psychology 102 (2010), 3, pp. 531-549, 102. https://doi.org/10.1037/a0019243

Pichora-Fuller, M. K. (2016). How social psychological factors may modulate auditory and cognitive functioning during listening. Ear and Hearing, 37, 92S-100S. https://doi.org/10.1097/aud.0000000000000323

Pichora‐Fuller, M. K., Schneider, B. A., & Daneman, M. (1995). How young and old adults listen to and remember speech in noise. The Journal of the Acoustical Society of America, 97(1), 593-608. https://doi.org/10.1121/1.412282

Rosemann, S., & Thiel, C. M. (2019). The effect of age-related hearing loss and listening effort on resting state connectivity. Sci Rep, 9(1), 2337. https://doi.org/10.1038/s41598-019-38816-z

Rowe, A. D., & Fitness, J. (2018). Understanding the Role of Negative Emotions in Adult Learning and Achievement: A Social Functional Perspective. Behavioral Sciences, 8(2), 27. https://www.mdpi.com/2076-328X/8/2/27

Sakai, K. L., Kuwamoto, T., Yagi, S., & Matsuya, K. (2021). Modality-Dependent Brain Activation Changes Induced by Acquiring a Second Language Abroad. Front Behav Neurosci, 15, 631957. https://doi.org/10.3389/fnbeh.2021.631957

Sanchez-Perez, N., Inuggi, A., Castillo, A., Campoy, G., Garcia-Santos, J. M., Gonzalez- Salinas, C., & Fuentes, L. J. (2019). Computer-based cognitive training improves brain functional connectivity in the attentional networks: a study with primary school- aged children. Front Behav Neurosci, 13, 247. https://doi.org/10.3389/fnbeh.2019.00247

Sarant, J., Harris, D., Busby, P., Maruff, P., Schembri, A., Lemke, U., & Launer, S. (2020). The Effect of Hearing Aid Use on Cognition in Older Adults: Can We Delay Decline or Even Improve Cognitive Function? Journal of Clinical Medicine, 9(1), 254. https://www.mdpi.com/2077-0383/9/1/254

Schneider, B. A., Daneman, M., & Pichora-Fuller, M. K. (2002). Listening in aging adults: from discourse comprehension to psychoacoustics. Can J Exp Psychol, 56(3), 139-52. https://doi.org/10.1037/h0087392

Schneider, B. A., K., P.-F., & M., D. (2010). Effects of Senescent Changes in Audition and Cognition on Spoken Language Comprehension. The Aging Auditory System, Springer Handbook of Auditory Research, vol 34. https://doi.org/https://doi.org/10.1007/978-1-4419-0993-0_7

Schow, R., & Nerbonne, M. (2006). Introduction to audiologic rehabilitation. Schuknecht, H. F., & Gacek, M. R. (1993). Cochlear pathology in presbycusis. Ann Otol Rhinol Laryngol, 102(1 Pt 2), 1-16. https://doi.org/10.1177/00034894931020s101

Slade, K., Plack, C. J., & Nuttall, H. E. (2020). The effects of age-related hearing loss on the brain and cognitive function. Trends Neurosci, 43(10), 810-21. https://doi.org/10.1016/j.tins.2020.07.005

Smith, E. E., & Jonides, J. (1999). Storage and executive processes in the frontal lobes. Science, 283(5408), 1657-61. https://doi.org/10.1126/science.283.5408.1657

Sommers, M. S. (1997). Speech perception in older adults: the importance of speech-specific cognitive abilities. J Am Geriatr Soc, 45(5), 633-7. https://doi.org/10.1111/j.1532-5415.1997.tb03101.x

Stewart, H. J., Cash, E. K., Maloney, T., Vannest, J., & Moore, D. R. (2020). Effect of listening difficulties on speech cortical activation and connectivity in children. medRxiv, 2020.10.26.20218495. https://doi.org/10.1101/2020.10.26.20218495

Szameitat, A. J., Schubert, T., Muller, K., & Von Cramon, D. Y. (2002). Localization of executive functions in dual-task performance with fMRI. J Cogn Neurosci, 14(8), 1184-99. https://doi.org/10.1162/089892902760807195

Takeuchi, H., Taki, Y., Hashizume, H., Sassa, Y., Nagase, T., Nouchi, R., & Kawashima, R. (2012). The association between resting functional connectivity and creativity. Cereb Cortex, 22(12), 2921-9. https://doi.org/10.1093/cercor/bhr371

Takeuchi, H., Taki, Y., Nouchi, R., Hashizume, H., Sekiguchi, A., Kotozaki, Y., Nakagawa, S., Miyauchi, C. M., Sassa, Y., & Kawashima, R. (2014). Effects of multitasking- training on gray matter structure and resting state neural mechanisms. Hum Brain Mapp, 35(8), 3646-60. https://doi.org/10.1002/hbm.22427

Taljaard, D. S., Olaithe, M., Brennan-Jones, C. G., Eikelboom, R. H., & Bucks, R. S. (2016). The relationship between hearing impairment and cognitive function: a meta-analysis in adults. Clinical Otolaryngology, 41(6), 718-29. https://doi.org/https://doi.org/10.1111/coa.12607

Tombu, M. N., Asplund, C. L., Dux, P. E., Godwin, D., Martin, J. W., & Marois, R. (2011). A Unified attentional bottleneck in the human brain. Proc Natl Acad Sci U S A, 108(33), 13426-31. https://doi.org/10.1073/pnas.1103583108

Tsukiura, T., Fujii, T., Takahashi, T., Xiao, R., Sugiura, M., Okuda, J., Iijima, T., & Yamadori, A. (2002). Medial temporal lobe activation during context-dependent relational processes in episodic retrieval: an fMRI study. Functional magnetic resonance imaging. Hum Brain Mapp, 17(4), 203-13. https://doi.org/10.1002/hbm.10068

Uhlmann, R. F., Larson, E. B., Rees, T. S., Koepsell, T. D., & Duckert, L. G. (1989). Relationship of hearing impairment to dementia and cognitive dysfunction in older adults. JAMA, 261(13), 1916-9. https://www.ncbi.nlm.nih.gov/pubmed/2926927

Ventry, I. M., & Weinstein, B. E. (1982). The hearing handicap inventory for the elderly: a new tool. Ear Hear, 3(3), 128-34. https://doi.org/10.1097/00003446-198205000-00006

Vincent, J. L., Kahn, I., Snyder, A. Z., Raichle, M. E., & Buckner, R. L. (2008). Evidence for a frontoparietal control system revealed by intrinsic functional connectivity. J Neurophysiol, 100(6), 3328-42. https://doi.org/10.1152/jn.90355.2008

Walden, P. R., & Khayumov, J. (2020). The use of auditory-perceptual training as a research method: a summary review. Journal of Voice. https://doi.org/https://doi.org/10.1016/j.jvoice.2020.06.032

Wayne, R. V., & Johnsrude, I. S. (2015). A review of causal mechanisms underlying the link between age-related hearing loss and cognitive decline. Ageing Res, 23(Pt B), 154-66. https://doi.org/10.1016/j.arr.2015.06.002

Wechsler, D. (1987). Wechsler Memory Scale Revised. San Antonio, TX:The Psychological Corporation.

Wechsler, D. (1997). Wechsler Adult Intelligence Scale. 3rd Edn. San Antonio, TX: The Psychological Corporation.

WHO. (2011). World Health Organization Global Health and Aging. National Institutes of Health 1-32. https://www.who.int/ageing/publications/global_health.pdf

World Medical, A. (1991). Declaration of Helsinki. Law Med Health Care, 19(3-4), 264-5. https://www.ncbi.nlm.nih.gov/pubmed/11642954

Wu, T., Liu, J., Hallett, M., Zheng, Z., & Chan, P. (2013). Cerebellum and integration of neural networks in dual-task processing. Neuroimage, 65, 466-75. https://doi.org/10.1016/j.neuroimage.2012.10.004

Yamasoba, T., Lin, F. R., Someya, S., Kashio, A., Sakamoto, T., & Kondo, K. (2013). Current concepts in age-related hearing loss: epidemiology and mechanistic pathways. Hear Res, 303, 30-8. https://doi.org/10.1016/j.heares.2013.01.021

Yusof, Y., Mukari, S. Z. S., Dzulkifli, M. A., Chellapan, K., Ahmad, K., Ishak, I., Maamor, N., & Ishak, W. S. (2019). Efficacy of a newly developed auditory-cognitive training system on speech recognition, central auditory processing and cognitive ability among older adults with normal cognition and with neurocognitive impairment. Geriatr Gerontol Int, 19(8), 768-73. https://doi.org/10.1111/ggi.13710

参考文献をもっと見る

全国の大学の
卒論・修論・学位論文

一発検索!

この論文の関連論文を見る