肥満・2型糖尿病に関連した分子群の生理学的意義の解明
概要
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3. E *$/%,xwIU.......................................................................... 10
4. ARID'*,1l ~T
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5 b\ ]o ....................................................................................................................... 21
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2. J° PCR............................................................................................................................... 22
3.
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4. Gª®ApSqJ................................................................................................................... 26
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4-2. ®®ApSqJ....................................................................................................... 26
5. 6©u°J° /®CWpSqJ................................................................ 27
6. ¶hg®X= J°................................................................................................ 27
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B«pSqJ................................................................................................ 28
9. ?6NF³>A¦K........................................................................ 29
10. Qª
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11. ;<}f.......................................................................................................................... 30
12. ¤¢d.................................................................................................................................. 30
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4. */¯±!'1+v¢d ............................................................................ 32
5. ¥µ¶h
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6. Exm
GLUT4 Aj[p
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^9_ h@................................................. .................................................................................. 50
^ . ] Y n l i a j
GDE5 P k q M ................................................................. 55
^*_ er.................................................................................................................................... 55
^._ LJKQ........................................................................................................................ 59
1. aj........................................................................................................................................... 59
2. aj;%(
$(aj?S>........................................... 59
3. LC-MS/MS qM....................................................................................................................... 60
4. (!'Q
(xXVqM....................................................... 60
5. Oil Red O On.......................................................................................................................... 61
6. >Z PCR............................................................................................................................... 61
7. Bromodeoxyuridine 7z.................................................................................. 62
8. DNA "'&qM..................................................................................................... 62
9. #B`TCS>....................................................................................... 63
10. csqM................................................................................................................................. 63
^+_ bN.................................................................................................................................... 64
1. 3T3-L1 aj
GDE5 XV)(qM......................................................... 64
2. GDE5 XVH4
aj1 choline /w<6...................................................... 64
3. GDE5 XVH4
aj1
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26
|~0=gXVqM.................................................................................... 64
4. GDE5 XVH4
MCE
FqM................................................................. 65
5. DNA "'&Q3WdfZ ~0=XV<5qM............................. 66
6. GDE5 XVH4
ajR{:u_
qM.............................................. 66
7. GDE5 XVH4
ajm{}G<6................................................................... 67
^9_ h@.................................................................................................................................,. 81
c 8 t v .............................................................................................................................................. 83
D W I U .............................................................................................................................................. 88
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