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Acknowledgements
We are extremely grateful to participants in the present study and collaborated nursing staff in the hospital. This
work was supported by JSPS KAKENHI Grant Number JP22K21239.
Author contributions
Conception and design: H.T., G.K., Masashi.T., and N.I. Acquisition of data: H.T., G.K., and Mayu.T. Analysis
and interpretation of data: H.T., G.K., Mayu.T., M.N., Masashi.T., and N.I. Drafting the article: H.T., G.K., M.N.,
Masashi.T., T.K., and T.M. Critically revising the article: R.I., Susumu.M., R.T., Shuichi.M., and N.I. Reviewed
submitted version of manuscript: all authors. Statistical analysis: H.T., Masashi.T. Administrative/technical/
material support: R.I., Shuichi.M. Study supervision: Susumu.M., R.T., Shuichi.M., and N.I.
Competing interests The authors declare no competing interests.
Additional information
Correspondence and requests for materials should be addressed to H.T.
Reprints and permissions information is available at www.nature.com/reprints.
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