1 Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall
JO: Exosome-mediated transfer of mRNAs and microRNAs is a
novel mechanism of genetic exchange between cells. Nat Cell
Biol 9(6): 654-659, 2007. DOI: 10.1038/ncb1596
415
Inubushi et al: Methionine Restriction Increases Exosomes
10
11
12
13
14
15
16
17
18
H3 lysine increases with degree of malignancy and methionine
addiction. Cancer Genomics Proteomics 19(1): 12-18, 2022.
DOI: 10.21873/cgp.20299
Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara
K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG,
Nishida K, Hoffman RM: Reversion of methionine addiction of
osteosarcoma cells to methionine independence results in loss of
malignancy, modulation of the epithelial-mesenchymal phenotype
and alteration of histone-H3 lysine-methylation. Front Oncol 12:
1009548, 2022. DOI: 10.3389/fonc.2022.1009548
Hoffman RM, Jacobsen SJ, Erbe RW: Reversion to methionine
independence in simian virus 40-transformed human and
malignant rat fibroblasts is associated with altered ploidy and
altered properties of transformation. Proc Natl Acad Sci USA
76(3): 1313-1317, 1979. DOI: 10.1073/pnas.76.3.1313
Hoffman RM, Jacobsen SJ, Erbe RW: Reversion to methionine
independence by malignant rat and SV40-transformed human
fibroblasts. Biochem Biophys Res Commun 82(1): 228-234,
1978. DOI: 10.1016/0006-291x(78)90600-9
Kubota Y, Sato T, Hozumi C, Han Q, Aoki Y, Masaki N, Obara
K, Tsunoda T, Hoffman RM: Superiority of [(11)C]methionine
over [(18)F]deoxyglucose for PET Imaging of Multiple Cancer
Types Due to the Methionine Addiction of Cancer. Int J Mol Sci
24(3): 1935, 2023. DOI: 10.3390/ijms24031935
Stern PH, Wallace CD, Hoffman RM: Altered methionine
metabolism occurs in all members of a set of diverse human
tumor cell lines. J Cell Physiol 119(1): 29-34, 1984. DOI:
10.1002/jcp.1041190106
Hoffman RM, Coalson DW, Jacobsen SJ, Erbe RW: Folate
polyglutamate and monoglutamate accumulation in normal and
SV40-transformed human fibroblasts. J Cell Physiol 109(3):
497-505, 1981. DOI: 10.1002/jcp.1041090316
Mecham JO, Rowitch D, Wallace C, Stern PH, Hoffman RM: The
metabolic defect of methionine dependence occurs frequently in
human tumor cell lines. Biochem Biophys Res Commun 117(2):
429-434, 1983. DOI: 10.1016/0006-291x(83)91218-4
Stern PH, Hoffman RM: Elevated overall rates of
transmethylation in cell lines from diverse human tumors. In
Vitro 20(8): 663-670, 1984. DOI: 10.1007/BF02619617
Judde JG, Ellis M, Frost P: Biochemical analysis of the role of
transmethylation in the methionine dependence of tumor cells.
Cancer Res 49(17): 4859-4865, 1989.
Hoffman RM, Jacobsen SJ: Reversible growth arrest in simian
virus 40-transformed human fibroblasts. Proc Natl Acad Sci U
S A 77(12): 7306-7310, 1980. DOI: 10.1073/pnas.77.12.7306
Yano S, Li S, Han Q, Tan Y, Bouvet M, Fujiwara T, Hoffman RM:
Selective methioninase-induced trap of cancer cells in S/G2 phase
visualized by FUCCI imaging confers chemosensitivity. Oncotarget
5(18): 8729-8736, 2014. DOI: 10.18632/oncotarget.2369
Sugimura T, Birnbaum SM, Winitz M, Greenstein JP:
Quantitative nutritional studies with water-soluble, chemically
defined diets. VIII. The forced feeding of diets each lacking in
one essential amino acid. Arch Biochem Biophys 81(2): 448455, 1959. DOI: 10.1016/0003-9861(59)90225-5
416
19 Suetsugu A, Honma K, Saji S, Moriwaki H, Ochiya T, Hoffman
RM: Imaging exosome transfer from breast cancer cells to stroma
at metastatic sites in orthotopic nude-mouse models. Adv Drug
Deliv Rev 65(3): 383-390, 2013. DOI: 10.1016/j.addr.2012.08.007
20 Otsuka K, Yamamoto Y, Ochiya T: Uncovering temperaturedependent extracellular vesicle secretion in breast cancer. J
Extracell Vesicles 10(2): e12049, 2020.
21 Inubushi S, Kawaguchi H, Mizumoto S, Kunihisa T, Baba M,
Kitayama Y, Takeuchi T, Hoffman RM, Tanino H, Sasaki R:
Oncogenic miRNAs identified in tear exosomes from metastatic
breast cancer patients. Anticancer Res 40(6): 3091-3096, 2020.
DOI: 10.21873/anticanres.14290
22 Kaiser P: Methionine dependence of cancer. Biomolecules 10(4):
568, 2020. DOI: 10.3390/biom10040568
23 Chello PL, Bertino JR: Dependence of 5-methyltetrahydrofolate
utilization by L5178Y murine leukemia cells in vitro on the
presence of hydroxycobalamin and transcobalamin II. Cancer
Res 33(8): 1898-1904, 1973.
24 Halpern BC, Clark BR, Hardy DN, Halpern RM, Smith RA: The
effect of replacement of methionine by homocystine on survival
of malignant and normal adult mammalian cells in culture. Proc
Natl Acad Sci USA 71(4): 1133-1136, 1974. DOI: 10.1073/
pnas.71.4.1133
25 Ashe H, Clark BR, Chu F, Hardy DN, Halpern BC, Halpern RM,
Smith RA: N5-methyltetrahydrofolate: Homocysteine methyl
transferase activity in extracts from normal, malignant and
embryonic tissue culture cells. Biochem Biophys Res Commun
57(2): 417-425, 1974. DOI: 10.1016/0006-291x(74)90947-4
26 Sullivan MR, Darnell AM, Reilly MF, Kunchok T, Joesch-cohen
L, Rosenberg D, Ali A, Rees MG, Roth JA, Lewis CA, Vander
Heiden MG: Methionine synthase is essential for cancer cell
proliferation in physiological folate environments. Nat Metab
3(11): 1500-1511, 2021. DOI: 10.1038/s42255-021-00486-5
27 Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N,
Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke
SG, Endo I, Hoffman RM: Linkage of methionine addiction,
histone lysine hypermethylation, and malignancy. iScience
25(4): 104162, 2022. DOI: 10.1016/j.isci.2022.104162
28 Yamamoto J, Han Q, Simon M, Thomas D, Hoffman RM:
Methionine Restriction: Ready for Prime Time in the Cancer
Clinic? Anticancer Res 42(2): 641-644, 2022. DOI: 10.21873/
anticanres.15521
Received May 25, 2023
Revised July 3, 2023
Accepted July 18, 2023
...
論文の公開元へ
