1. T. Nisisako, “Recent advances in microfluidic production of Janus droplets and particles,” Curr. Opin. Colloid Interface Sci. 25, 1–12 (2016). https://doi.org/10.1016/j.cocis.2016.05.003.
2. S. Lone, I.W. Cheong, “Fabrication of polymeric Janus particles by droplet microfluidics,” RSC Adv. 4, 13322–13333 (2014). https://doi.org/10.1039/c4ra00158c.
3. T. Nisisako, T. Torii, T. Takahashi, Y. Takizawa, “Synthesis of monodisperse bicolored Janus particles with electrical anisotropy using a microfluidic co-flow system,” Adv. Mater. 18, 1152– 1156 (2006). https://doi.org/10.1002/adma.200502431.
4. C. C asagramde, P. Fabre, E. Raphael, M. Veyssie, “Janus beads: Realization and behaviour at water/oil interfaces,” Europhys. Lett. 9, 251–255 (1989). https://doi.org/10.1209/0295-5075/9/3/011.
5. S. Berger, A. Synytska, L. Ionov, K.J. Eichhorn, M. Stamm, “Stimuli-responsice bicomponent polymer Janus particles by ‘Grafting from’/‘Grafting’ to approaches,” Macromolecules 41, 9669– 9676 (2008). https://doi.org/10.1021/ma802089h.
6. Y. Du, E. Lo, S. Ali, A. Khademhosseini, “Direct assembly of cell-laden microgels for fabrication of 3D tissue constructs,” PNAS 105, 9522–9527 (2008). https://doi.org/10.1073/pnas.0801866105.
7. W.F. Lai, A.S. Susha, A.L. Rogach, “Multicompartment microgel beads for co-delivery of multiple drugs at individual release rates,” ACS Appl. Mater. Interfaces 8, 871–880 (2016). https://doi.org/10.1021/acsami.5b10274.
8. V. Rastogi, S. Melle, O.G. Calderon, A.A. Garcia, M. Marquez, O.D. Velev, “Synthesis of light- diffreacting assemblies from microspheres and nanoparticles in droplets on a superhydrophobic surface,” Adv. Mater. 20, 4263–4268 (2008). https://doi.org/10.1002/adma.200703008.
9. Y. Komazaki, H. Hirama, T. Torii, “Electrically and magnetically dual-driven Janus particles for handwriting-enabled electronic paper,” J. Appl. Phys. 117, 154506 (2015). https://doi.org/10.1063/1.4917379.
10. J.N. Anker, C. Behrend, R. Kopelman, “Aspherical magnetically modulated optical nanoprobes (MagMOONs),” J. Appl. Phys. 93, 6698–6700 (2003). https://doi.org/10.1063/1.1556926.
11. B. Ren, A. Ruditskiy, J.H. Song, I. Kretzschmar, “Assembly behavior of iron oxide-capped Janus particles in a magentic field,” Langmuir 28, 1149–1156 (2012). https://doi.org/10.1021/la203969f.
12. L. Baraban, D. Makarov, R. Streubel, I. Monch, D. Grimm, S. Sanchez, O.G. Schmidt, “Catalytic Janus motors on microfluidic chip: deterministic motion for targeted cargo delivery,” ACS Nano 6, 3383–3389 (2012). https://doi.org/10.1021/nn300413p.
13. L.O. Mair, B. Evans, A.R. Hall, J. Carpenter, A. Shields, K. Ford, M. Millard, R. Superfine, “Highly controllable near-surface swimming of magnetic Janus nanorods: application to payload capture and manipulation,” J. Phys. D: Appl. Phys. 44, 125001 (2011). https://doi.org/10.1088/0022-3727/44/12/125001.
14. H. Wang, S. Yang, S.N. Yin, L. Chen, S. Chen, “Janus suprabead displays derived from the modified photonic crystals toward temperature magnetism and optics multiple responses,” ACS Appl. Mater. Interfaces 7, 8827–8833 (2015). https://doi.org/10.1021/acsami.5b01436.
15. K. Maeda, H. Onoe, M. Takinoue, S. Takeuchi, “Controlled synthesis of 3D multt-copmpartmental particles with centrifuge-based microdroplet formation from a multi-barrelled capillary,” Adv. Mater. 24, 1340–1346 (2012). https://doi.org/10.1002/adma.201102560.
16. L.B. Zhao, L. Pan, K. Zhang, S.S. Guo, W. Liu, Y. Wang, Y. Chen, X.Z. Zhao, H.L.W. Chen, “Generation of Janus alginate hydrogel particles with magnetic anisotropy for cell encapsulation,” Lab on chip 9, 2981–2986 (2009). https://doi.org/10.1039/b907478c.
17. K.P. Yuet, D.K. Hwang, R. Haghgooie, P.S. Doyle, “Multifunctional superparamagnetic Janus particles,” Langmuir 26, 4281–4287 (2010). https://doi.org/10.1021/la903348s.
18. J. Lan, J.Chen, N. Li, X. Ji, M. Yu, Z. He, “Microfluidic generation of magnetic-fluorescent Janus microparticles for biomolecular detection,” Talanta 151, 126–131 (2016). https://doi.org/10.1016/j.talanta.2016.01.024.
19. P. Alivisatos, “The use of nanocrystals in biological detection,” Nat. Biotechnol. 22, 47–52 (2004). https://doi:10.1038/nbt927.
20. V. Stsiapura, A. Sukhanova, M. Artemyev, M. Pluot, J.H.M. Cohen, A.V. Baranov, V. Oleinikov, I. Nabiev, “Functionalized nanocrystal-tagged fluorescent polymer beads: synthesis, physicochemical characterication, and immunolabeling application,” Anal. Biochem. 334, 257– 265 (2004). https://doi.org/10.1016/j.ab.2004.07.006.
21. B.M. Teo, D.J. Young, X.J. Loh, “Magnetic anisotropic particles: toward remotely actuated applications,” Part. Part. Syst. Charact. 33, 709–728 (2016). https://doi.org/10.1002/ppsc.201600060.
22. C. Xu, B. Wang, S. Sun, “Dumbbell-like Au-Fe3O4 nanoparticles for target-specific platin delivery,” J. Am. Chem. Soc. 131, 4216–4217 (2009). https://doi.org/10.1021/ja900790v.
23. S.H. Hu, X. Gao, “Manocomposites with spatially separated functionalities for combined imaging and magnetolytic therapy,” J. Am. Chem. Soc. 132, 7234–7237 (2010). https://doi.org/10.1021/ja102489q.
24. X.Y. Ling, I.Y. Phand, C. Acikgoz, M.D. Yilmaz, M.A. Hempenious, G.J. Vancso, J. Huskens, “Janus particles with controllable patchiness and their chemical functionalization and supramolecular assembly,” Angew. Chem. Int. Ed. 48, 7677–7682 (2009). https://doi.org/10.1002/anie.200903579.
25. Y. Zhang, Y. Wan, Y. Liao, Y. Hu, T. Jiang, T. He, W. Bi, J. Lin, P. Gong, L. Tang, et al., “Janus γ- Fe2O3/SiO2-based nanotheranostics for dual-modal imaging and enhanced synergistic cancer starvation/chemodynamic therapy,” Science Bulletin 65, 564–572 (2020). https://doi.org/10.1016/j.scib.2019.12.024.
26. H. Yabu, M. Kanahara, M. Shimomura, T. Arita, K. Harano, E. Nakamura, T. Higuchi, H. Jinnai, “Polymer Janus particles containing block-copolymer stabilized magnetic nanoparticles,” ACS Appl. Mater. Interfaces 5, 3262–3266 (2013). https://doi.org/10.1021/am4003149.
27. K.H. Roh, D.C. Martin, A.J. Lahann, “Biphasic Janus particles with nanoscale anisotropy,” Nature Mater. 4, 759–763 (2005). https://doi.org/10.1038/nmat1486.
28. S.N. Yin, C.F. Wang, Z.Y. Yu, J. Wang, S.S. Liu, S. Chen, “Versatile bifunctional magnetic- fluorescnet responsive Janus supraballs towards the flexible bead display,” Adv. Mater. 23, 2915– 2919 (2011). https://doi.org/10.1002/adma.201100203.
29. Y. Zhao, H.C. Shum, H. Chen, L.L.A. Adams, Z. Gu, D.A. Weitz, “Microfluidic generation of multifunctional quantum dot barcode particles,” J. Am. Chem. Soc. 133, 8790–8793 (2011). https://doi.org/10.1021/ja200729w.
30. R.K. Shah, J.W. Kim, D.A. Weitz, “Janus supraparticles by induced phase separation of nanoparticles in droplets,” Adv. Mater. 21, 1949–1953 (2009). https://doi.org/10.1002/adma.200803115.
31. S.H. Kim, J.Y. Sim, J.M. Lim, S.M. Yang, “Magnetoresponsive microparticles with nanoscopic surface structures for remote-controlled locomotion,” Angew. Chem. 49, 3786–3790 (2010). https://doi.org/10.1002/anie.201001031.
32. S. Li, X. Yu, S. You, B. Cai, C. Liu, H. Liu, W. Liu, S.S. Guo, X.Z. Zhao, “Generation of BiFeO3- Fe3O4 Janus particles based on droplet microfluidic method,” Appl. Phys. Lett. 105, 042903 (2014).
33. S. Yoshida, M. Takinoue, E. Iwase, H. Onoe, “Dynamic transformation of self-assembled structures using anisotropic magnetized hydrogel microparticles,” J. Appl. Phys. 120, 084905 (2016). https://doi.org/10.1063/1.4961422.
34. P. Aslani, R.A. Kennedy, “Effect of gelation conditions and dissolution media on the release of paracetamol from alginate gel beads,” J. Microencapsulation 13, 601–614 (1996). https://doi.org/10.3109/02652049609026044.
35. L. Zhang, K. Chen, H. Zhang, B. Pang, C.H. Choi, A.S. Mao, H. Liao, S. Utech, D.J. Mooney, H. Wang, D.A. Weitz, “Microfluidic templated multicompartment microgels for 3D encapsulation and paring of single cells,” Small 14, 1702955 (2018). https://doi.org/10.1002/smll.201702955.
36. Aketagawa, H. Hirama, T. Torii, “Hyper-miniaturisation of monodisperse Janus hydrogel beads with magnetic anisotropy based on coagulation of Fe3O4 nanoparticles,” J. Mater. Sci. Chem. Eng. 1, 1–5 (2013). https://doi.org/10.4236/msce.2013.12001
37. Y. Liu, N. Tottori, T. Nisisako, “Microfluidic synthesis of highly spherical calcium alginate hydrogels based on external gelation using an emulsion reactant,” Sensors Actuators, B Chem. 283, 802–809 (2019). https://doi.org/10.1016/j.snb.2018.12.101.
38. W.H. Tan, S. Takeuchi, “Monodisperse alginate hydrogel microbeads for cell encapsulation,” Adv. Mater. 19, 2696–2701 (2007). https://doi.org/10.1002/adma.200700433.
39. A. Einstein, “Investigations on the theory of Brownian movement,” (Dover Publications, New York, 1956).
40. A.S. Utada, E. Lorenceau, D.R. Link, P.D. Kaplan, H.A. Stone, D.A. Weitz, “Monodisperse double emulsions generated from a microcapillary device,” Science 308, 537–541 (2005). https://doi.org/10.1126/science.1109164.
41. C.K. Kuo, P.X. Ma, “Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: Part 1. Structure, gelation rate and mechanical properties,” Biomaterials 22, 511–521 (2001). https://doi.org/10.1016/s0142-9612(00)00201-5.
42. A.W. Chan, R.J. Neufeld, “Tuneable semi-synthetic network alginate for absorptive encapsulation and controlled release of protein therapeutics,” Biomaterials 31, 9040–9047 (2010). https://doi.org/10.1016/j.biomaterials.2010.07.111.
43. R.G. Thomas, A.R. Unnithan, M.J. Moon, S.P. Surendran, T. Batgerel, C.H. Park, C.S. Kim, Y.Y. Jeong, “Electromagnetic manipulation enabled calcium alginate Janus microsphere for targeted delivery of mesenchymal stem cells,” Int. J. Biol. Macromol. 110, 465–471 (2018). https://doi.org/10.1016/j.ijbiomac.2018.01.003.
44. C. Simpliciano, L. Clark, B. Asi, N. Chu, M. Mercado, S. Diaz, M. Goedert, M. Mobed-Miremadi, J. Surf. Eng. Mater. Adv. Technol. 3, 1-12 (2013). http://dx.doi.org/10.4236/jsemat.2013.34A1001.
45. L. Ponsonnet, K. Reybier, N. Jaffrezic, V. Comte, C. Lagneau, M. Lissac, C. Martelet, “Relationship between surface properties (roughness, wetability) of titanium and titanium alloys and cell behavior,” Mater. Sci. Eng. C 23, 551–560 (2003). https://doi.org/10.1016/S0928-4931(03)00033-X.
46. N.J. Hallab, K.J. Bundy, K. O’Connor, R.L. Moses, J.J. Jacobs, “Evaluation of metallic and polymeric biomaterials surface energy and surface roughness characteristics for directed cell adhesion,” Tissue Engineering 7, 55–71 (2001). https://doi.org/10.1089/107632700300003297.
47. A.B. Pawar, I. Kretzschmar, “Fabrication, assembly, and application of patchy particles,” Macromol. Rapid Commun. 31, 150–168 (2010). https://doi.org/10.1002/marc.200900614.
48. X.T. Sun, Y. Zhang, D.H. Zhang, S. Yue, C.G. Yang and Z.R. Xu, “Multitraget sensing of glucose and cholesterol based on Janus hydrogel microparticles,” Biosens. Bioelectron. 92, 81–86 (2017). https://doi.org/10.1016/j.bios.2017.02.008.