体・生理工学シンポジウム論文集（BPES）2009；24：
１．
高齢化の現状と将来像 平成30年度版高齢社会白書
（全 体 版 ）－ 内 閣 府 https://www8.cao.go.jp/kourei/
381-384
15．
Hoshi Y, Kobayshi N, Tamura M: Interpretation
of near-infrared spectroscopy signals: a study with
whitepaper/w-2018/html/zenbun/s1_1_1.html（閲覧
a newly developed perfused rat brain model. J Appl
日：2019.7.30）
２．
小田清一，稲木杏吏，貝沼圭，玉井裕也，原総一朗，
三山江穂他：国民衛生の動向 Vol.65 No.9 2018/2019．
Physiol 2001; 29
（4）
: 329-338
16．
Gusnard DA, Raichle ME: Searching for a baseline:
Functional imaging and the resting human brain.
東京；一般財団法人厚生労働統計協会 2018；131, 134,
248, 259-260
３．
茂野香おる，有田清子，守本とも子，吉村雅世，岡本
Neuroscience 2001; vol
（2）
: 685-694
17．
Raichle ME, Macleod AM, Snyder AZ, Powers WJ,
Gusnard DA, Shulman GL: A default mode of brain
啓子：清潔・衣生活援助技術．仁和子：系統看護学講座
専門分野Ⅰ 基礎看護学［3］基礎看護技術Ⅱ．東京；
医学書院 2015；185-186, 190, 192
function. PNAS 2001; vol.98 no.2: 676-682
18． Morita T, Asada M, Naito E: Developmental
Changes in Task-Induced Brain Deactivation in
４．
Kato H, Takahashi Y, Iseki C, Igari R, Sato H, Sato
Humans Revealed by a Motor Task. Developmental
H, et al. : Tooth Loss-associated cognitive Impairment
in the Elderly: A Community-based Study in Japan.
Internal Medicine 2019; 58: 1411-1416
Neurobiology 2019; 1-18
19．
Shimada S, Hiraki K, Matsuda G, Oda I: Decrease
in prefrontal hemoglobin oxygenation during reaching
５．
水野潤造，森田十誉子，山崎洋治，渋谷耕司，久保金
tasks with delayed visual feedback: a near-infrared
弥，丹羽政美他：ブラッシングによる脳賦活：fMRIに
spectroscopy study. Cognitive Brain Research 2004; 20:
よる研究 成人における基礎的解析．老年歯学 2008；
第23巻第３号：330-337
６．
森田婦美子，山本純子，高橋弘枝：脳の活性化を促す
480-490
20．
Joung D, Kim G, Choi Y, Lim H, Park S, Woo JM, et
al. : The Prefrontal Cortex Activity and Psychological
口腔内刺激 近赤外光イメージング装置を用いた脳血流
Effects of Viewing Forest Landscapes in Autumn
量の測定を行って．太成学院大学紀要 2012；第14巻：
Season. International Journal of Environmental
149-154
７．
力丸哲也，大倉義文，栢豪洋：口腔内ブラッシングに
よる大脳前頭前野の活性変化についての検討－近赤外分
Research and Public Health 2015; 12: 7236-7243
21．
Suda M, Sato T, Kameyama M, Ito M, Suto T,
Yamagishi Y, et al. : Decreased cortical reactivity
光法を用いた機能局在の解析－．老年歯学 2015；第29
underlies subjective daytime light sleepiness in healthy
巻第４号：329-339
subjects: A multichannel near-infrared spectroscopy
８．
晴山婦美子，塚本敦美，坂本まゆみ：看護に役立つ
口腔ケアテクニック第２版．医歯薬出版株式会社 2019
９．
瀬野晋一郎：口腔および口唇領域の電気刺激に対する
知覚閾値．生体医工学 2011；第49巻６号：925-931
10． Okamoto M, Dan H, Sakamoto K, Takeo K, Shimizu
K, Kohno S, et al. : Three-dimensional probabilistic
anatomical cranio-cerebral correlation via the
study. Neuroscience Research 2008; 60: 319-326
22．
渡邊裕文：中枢神経系の機能解剖－運動出力系－．関
西理学 2005；5：23-29
23．
岡本泰昌：ストレスを感じる前頭前野－ストレス適応
破綻の脳内機構－．日薬理誌 2005；126：194-198
24． Hoshi Y, Huang J, Kohri S, Iguchi Y, Naya M,
Okamoto T, et al. : Recognition of Human Emotions
international 10-20 system oriented for transcranial
from Cerebral Blood Flow Changes in the Frontal
functional brain mapping. NeuroImage 2007; 21: 99-111
Region: A Study with Event-Related Near-Infrared
11．
住谷さつき：NIRS研究と臨床への応用．脳と精神の
Spectroscopy. Journal of Neuroimaging 2011; Vol.21
医学 2009；第20巻第３号：163-169
12．
宮嶋めぐみ，廣安知之，山本詩子：fNIRSの原理と
データ処理方法．IS Report Medical System Laboratory
No.2: 94-101
25． 山本修一，柳沢一機，綱島均：NIRSを用いた快・不
2014；20141003：1-11
－84－
快画像提示時の脳活動の評価に関する研究．日本大学生
口腔ケアによる前頭前野脳血流量への影響の検討
産工学部第45回学術講演会講演概要 2012；173-176
26． 下山和弘，海野雅浩，大渡凡人，内田達郎，早川巌，
長尾正憲，他：高齢歯科患者の口腔不快症状の実態－口
腔乾燥感，口腔内粘稠感，味覚の異常感－．老年歯学
1995；第９巻第３号：149-158
－85－
Yamagata Med J（ISSN 0288-030X）2020；38
小杉，村上，三枝，石田，松田，櫻田
（2）
：75-86
DOI 10.15022/00004879
Effects of oral care using a toothbrush and sponge brush on
prefrontal cortex activity in healthy young adults
Naoko Kosugi＊，＊＊， Narumi Murakami＊， Makoto Saegusa＊＊， Yoko Ishida＊＊＊，
Yumi Matsuda＊＊＊＊， Kaori Sakurada＊＊＊
Yamagata University Faculty of Medicine, Graduate School of Nursing
＊＊
Division of Nursing, Yamagata University Hospital
＊＊＊
Department of Fundamental Nursing, Yamagata University Faculty of Medicine, School of Nursing
＊＊＊＊
Department of Community Nursing, Yamagata University Faculty of Medicine, School of Nursing
ABSTRACT
Background: Oral health care is one of the main methods of preventive care in the aged. Although
some previous studies have reported an association between oral health care, including tooth
brushing, and prefrontal cortex activation, the effects of oral brushing depending on the brushing tool
remain unclear. Therefore, the aim of this study was to investigate the differences in the effects of
using a toothbrush compared with a sponge brush for brushing the upper and lower jaws on cerebral
blood flow.
Methods: The effects of tooth brushing on cerebral prefrontal cortex activation using each brushing
tool were assessed for both the upper and lower jaws of 28 young adults（mean age±standard
deviation, 20.96±1.86 years; age range, 19–27 years）using near-infrared spectroscopy.（NIRS）
Results: The results indicated that cerebral blood flow decreased in all tasks. When compared
by tool, brushing the lower jaw with a toothbrush significantly decreased cerebral blood flow. By
contrast, when compared by part, brushing the upper jaw with a sponge brush significantly decreased
cerebral blood flow. The reasons for the decreases in cerebral blood flow were considered to be
deactivation of the default mode network and increased feelings of relaxation and sleepiness.
Conclusion: The results of this study suggest that oral brushing using a sponge brush and
toothbrush for the upper and lower jaws, respectively, decreases cerebral blood flow.
Keywords: oral care, cerebral blood flow, NIRS
－86－
...
論文の公開元へ
