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Acknowledgements
We are grateful to Ms. Y. Iikura (The University of Tokyo) and Ms. Y. Takeda (The
University of Tokyo). We also thank Mr. K. Shirayama (Waseda University), and Mr.
N. Yajima (Waseda University) for their assistance. This work was supported in part by JSPS
KAKENHI Grant Numbers JP15H06691 [to Y. A.], JP18H01836 [to M. Shibata],
JP19H05257 [to M. Shibata], JP18H05229 [to M. Sugiyama], JP18H05534 [to H. K. and M.
Sugiyama] and JP20H00449 [to H. K.]. This work was also partly supported by JST CREST
Grant Number JPMJCR16G1 [to H. K. and T. K.], JST ERATO Grant Number JPMJER1901
[to H. K.], the Platform Project for Supporting Drug Discovery and Life Science Research
(BINDS) from AMED under Grant Number JP20am0101076 [to H. K.], and the project for
Construction of the basis for the advanced materials science and analytical study by the
innovative use of quantum beam and nuclear sciences in KURNS [to M. Sugiyama].
Author contributions
R.H., Y.A. and T.K. performed biochemical analyses, and Y.A. performed X-ray crystallography. A.O., K.M., R.I. and M. Sugiyama performed the SAXS analyses. M. Shibata
ARTICLE
performed the HS-AFM analyses. H.K. conceived, designed, and supervised all of the
work, and R.H., T.K. and H.K. wrote the paper. All of the authors discussed the results
and commented on the manuscript.
Competing interests
The authors declare no competing interests.
Additional information
Supplementary information The online version contains supplementary material
available at https://doi.org/10.1038/s42003-021-01707-z.
Correspondence and requests for materials should be addressed to H.K.
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