Dietary Isosaponarin is Intestinally Metabolized to Isovitexin, Most of Which are Excreted in Feces without Being Absorbed

1.

2.

3.

4.

5.

6.

7.

5. CONCLUSION

The present study showed that dietary

isosaponarin is hardly absorbed into the body

and

metabolized

to

isovitexin

in

the

gastrointestinal tract. In other words, the

bioavailability of isosaponarin is very low,

suggesting that they cannot be expected to have

beneficial functions as dietary isosaponarin. On

the other hand, most of isovitexin is excreted with

feces, but isovitexin and its catabolites by

intestinal microflora may be beneficial to human

declared

8.

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