1. Abe, C., H. Saito, H. Tomioka, and Y. Fukasawa. 1989. Production of a
monoclonal
antibody
specific
for
Mycobacterium
avium
and
immunological activity of the affinity-purified antigen. Infect. Immun.
57:1095-1099.
2. Adams, J. L., and C. J. Czuprynski. 1994. Mycobacterial cell wall
components induce the production of TNF-alpha, IL-1, and IL-6 by
bovine monocytes and the murine macrophage cell line RAW 264.7.
Microb. Pathog. 16:401-411.
3. Al-Attiyaf, R., A. S. Mustafa, A. T. Abal, A. S. M. El-Shamy, W.
Dalemans, and Y. A. W. Skeiky. 2004. In in vitro cellulare immune
responses to complex and newly defined recombinant antigens of
Mycobacterium tuberculosis. Clin. Exp. Immunol. 138:139-144.
4. Antognoli, M. C., H. I. Hirst, F. B. Garry, and M. D. Salman. 2007.
Immune response to and faecal shedding of Mycobacterium avium ssp.
paratuberculosis in young dairy calves, and the association between
test results in the calves and the infection status of their dams.
Zoonoses Public Health 54:152-159.
5. Balcewicz-Sablinska, M. K., H. Gan, and H. G. Remond. 1999.
Imterleukin
10
produced
by
macrophages
inoculated
with
Mycobacterium avium attenuates mycobacteria-induced apoptosis by
reduction of TNF-alpha activity. J. Infect. Dis. 180:1230-1237.
6. Bannantine J. P., and M. L. Paustian. 2006. Identification of diagnostic
proteins in Mycobacterium avium subspecies paratuberculosis by a
whole genome analysis approach. Methods Mol. Biol. 345:185-196.
76
7. Bannantine, J. P., E. Baechler, Q. Zhang, LL. Li, V. Kapur. 2002.
Genome
scale
comparison
of
Mycobacterium
avium
subsp.
paratuberculosis with Mycobacterium avium subsp. avium reveals
potential diagnostic sequences. J. Clin. Microbiol. 40:1303-1310.
8. Bannantine, J. P., and J. R. Stabel. 2000. HspX is present within
Mycobacterium
paratuberculosis-infected
macrophages
and
is
recognized by sera from some infected cattle. Vet. Microbiol. 76:343-358.
9. Beadle, F. R., C. C. Gallen, R. S. Conway, and R. M. Waterson. 1979.
Enoyl Coenzyme A hydratase activity in Escherichia coli. Evidence for
short and long chain specific enzymes and study of their associations.
J. Biol. Chem. 254:4387-4395.
10. Begg, D. J., and R. J. Whittington. 2008. Experimental animal infection
models for Johne’s disease, an infectious enteropathy caused by
Mycobacterium avium subsp. paratuberculosis. Vet. J. 176:129-145.
11. Burrells, C., C. J. Clarke, A. Colston, J. M. Kay, J. Porter, D. Little, and
J. M. Sharp. 1999. Interferon-gamma and interleukin-2 release by
lymphocytes derived from the blood, mesenteric lymph nodes and
intestines of normal sheep and those affected with paratuberculosis
(Johne’s disease). Vet. Immunol. Immunopathol. 68:139-148.
12. Burrells, C., N. F. Inglis, R. C. Davies, and J. M. Sharp. 1995. Detection
of specific T cell reactivity in sheep infected with Mycobacterium avium
subspecies silvaticum and paratuberculosis using two defined
mycobacterial antigens. Vet. Immunol. Immunopathol. 45:311-320.
13. Buza, J. J., H. Hikono, Y. Mori, R. Nagata, S. Hirayama, Aodon-geril, A.
M. Bari, Y. shu, N. M. Tsuji, and E. Momotani. 2004. Neutralization of
77
interleukin-10 significantly enhances gamma interferon expression in
peripheral blood by stimulation with Johne purified protein derivative
and by infection with Mycobacterium avium subsp. paratuberculosis in
experimentally infected cattle with paratuberculosis. Infect. Immun.
72:2425-2428.
14. Chaitra, M. G., S. Hariharaputran, N. R. Chandra, M. S. Shaila, and R.
Nayak. 2005. Defining putative T cell epitopes from PE and PPE
families of proteins of Mycobacterium tuberculosis with vaccine
potential. Vaccine. 23:1265-1272.
15. Chaubey K, S. Singh, A. Bhatia, R. Gupta, and S. Gupta. 2018.
Detection limits of recombinant secretaly proteins versus semi-purified
protoplasmic antigens for the diagnosis of spontaneous cases of
Mycobacterium avium subspecies paratuberculosis infection in
domestic ruminants. J. Vet. Sci. Technol. 9:1000552.
16. Chiodini, R. J. 1996. Immunology: Resistance to paratuberculosis. Vet.
Clin. North Am. Food Anim. Pract. 12:313-343.
17. Chiodini, R. J., H.J. Vankruiningen, and R. S. Merkal. 1984. Ruminant
paratuberculosis (Johne’s disease): the current status and future
prospects. Cornell Vet. 74:218-262.
18. Cole, S. T., R. Brosch, J. Parkhill, T. Garnier, C. Churcher, D. Harris, S.
V. Gordon, K. Eiglmeier, S. Gas, C. E. Barry Ⅲ, F. Tekaia, K. Badcock,
D. Basham, D. Brown, T. Chillingworth, R. Connor, R. Davies, K. Devlin,
T. Feltwell, S. Gentles, N. Hamlin, S. Holroyd, T. Hornsby, K. Jagels, A.
Krogh, J. McLean, S. Moule, L. Murphy, K. Oliver, J. Osborne, M. A.
Quail, M. –A. Rajandream, J. Rogers, S. Rutter, K. Seeger, J. Skelton,
78
R. Squares, S. Squares, J. E. Sulston, K. Taylor, S. Whitehead, and B.
G.
Barrell.
1998.
Deciphering
the
biology
of
Mycobacterium
tuberculosis from the complete genome sequence. Nature. 393:537-544.
19. Collins, M. T., S. J. Wells, K. R. Petrini, J. E. Collins, R. D. Schultz, and
R. H. Whitlock. 2005. Evaluation of five antibody detection test for
diagnosis of bovine paratuberculosis. Clin. Diagn. Lab. Immunol.
12:685-692.
20. Conti, P. D., D. Kempuraj, K. Kandere, M. Di Gioacchino, and R. C.
Barbacane. 2003. IL-10, an inflammatory / inhibitory cytokine, but not
always. Imunol. Lett. 86:123-129.
21. Cooper, A. M., D. K. Dalton, T.A. Stewart, J. P. Griffin, D. G. Russell,
and I. M. Orme. 1993. Disseminated tuberculosis in interferon gamma
gene-disrupted mice. J. Exp. Med. 178:2243-2247.
22. Coussens, P. M. 2001. Mycobacterium paratubrtculosis and the bovine
immune system. Anim. Health Res. Rev. 2:141-161.
23. Coussens, P. M., N. Verman, M. A. Coussens, M. D. Elftman, and A. M.
McNulty. 2004. Cytokine gene expression in peripheral blood
mononuclear cells and tissues of cattle infected with Mycobacterium
avium
subsp.
paratuberculosis:
evidence
for
an
inherent
proinflammatory gene expression pattern. Infect. Immun. 72:14091422.
24. Dekesel, M., P. Gilot, M. Coene, and C, Cocito. 1992. Composition and
immunological properties of the protein fraction of A36, a major antigen
complex of Mycobacterium paratuberculosis. Scand. J. Immunol.
36:201-212.
79
25. Dernivoix, K., V. Roupie, S. Welby, S. Roelandt, S. Viart, J. J. Letesson,
R. Wattiez, K. Huygen, and M. Govaerts. 2017. Field performance of six
Mycobacterium avium subsp. paratuberculosis antigens in a 20 h
interferon
gamma
release
assay
in
Belgium.
Vet.
Immunol.
Imunopathol. 189:17-27.
26. Fleischmann, R. D., D. Alland, J. A. Eisen, L. Carpenter, O. White, J.
Peterson, R. DeBoy, R. Dodson, M. Gwinn, D. Haft, E. Hickey, J. F.
Kolonay, W. C. Nelson, L. A. Umayam, M. Ermolaeva, S. L. Salzberg, A.
Delcher, T. Utterback, J. Weidman, H. Khouri, J. Gill, A. Mikula, W.
Bishai, W. R. Jacobs, Jr., J. C. Venter, and C. M. Fraser. 2002. Wholegenome comparison of Mycobacterium tuberculosis clinical and
laboratory strains. J. Bacteriol. 184:5479-5490.
27. Fujita, Y., T. Shimakata, and T. Kusaka. 1980. Purification of two forms
of enoyl-CoA hydratase from Mycobacterium smegmatis. J. Biochem.
88:1045-1050.
28. Gilot, P., M. Dekesel, M. Coene, and C. Cocito. 1992. Induction of
cellular
immune-reactions
by
A36,
an
antigen
complex
of
Mycobacterium paratuberculosis: comparison of A36 and Johnin
components. Scand. J. Immunol. 36:811-821.
29. Gilot, P., and C. Cociti. 1993. Comparative analysis of three sensitins
used in cutaneous testing for tuberculosis and paratuberculosis in
cattle. FEMS Microbiol. Lett. 110:307-311.
30. Griffiths, T. A., K. Rioux, and L. De Buck. 2008. Sequence
polymorphisms in a surface PPE protein distinguish types I, II, and III
of Mycobacterium avium subsp. paratuberculosis. J. Clin. Microbiol.
80
46:1207-1212.
31. Gumber, S., D. L. Taylor, I. B. Marsh, and R. J. Whittington. 2009.
Growth pattern and partial proteome of Mycobacterium avium subsp.
paratuberculosis during the stress response to hypoxia and nutrient
starvation. Vet. Microbiol. 133:344-357.
32. Gumber, S., and R. J. Whittington. 2009. Analysis of the growth pattern,
survival
and
proteome
of
Mycobacterium
avium
subsp.
paratuberculosis following exposure to heat. Vet. Microbiol. 136:82-90.
33. Haddad, J. J., N. E. Saade, and B. Safieh-Garanedian. 2003.
Interleukin-10 and the regulation of mitogen-actevated protein kinases:
are these signaling modules targets for the anti-inflammatory action of
this cytokine? Cell. Signal. 15:255-267.
34. Harris, N. B., and R. G. Barletta. 2001. Mycobacterium avium subsp.
paratuberculosis in veterinary medicine. Clin. Microbiol. Rev. 14:489512.
35. Hasan, Z., B. H. Shah, A. Mahmood, D. B. Young, and R. Hussain. 2003.
The effect of mycobacterial virulence and viability on MAP kinase
signaling
and
TNF
alpha
production
by
human
monocytes.
Tuberculosis. 83:299-309.
36. Hasonova, L., and I. Pavlik. 2006. Economic impact of paratuberculosis
in dairy cattle herds: a review. Vet. Med. 51:193-211.
37. Hope, J. C., M. L. Thom, P. A. McCormick, and C. J. Howard. 2004.
Interaction of antigen presenting cells with mycobacteria. Vet.
Immunol. Immunopathol. 100:187-195.
38. Hughes, V., J. McNair, S. Strain, C. Barry, J. McLuckie, M. Nath, G.
81
Caldow, and K. Stevenson. Gamma interferon responses to proteomedetermined specific recombinant proteins in cattle experimentally- and
naturally- infected with paratuberculosis. Res. Vet. Sci. 114:244-253.
39. Jark, U., I. Ringena, B. Franz, G. F. Gerlach, M. Beyerbach, and B.
Franz. 1997. Development of an ELISA technique for serodiagnosis of
bovine paratuberculosis. Vet. Microbiol. 57:189-198.
40. Jungersen, G., A. Huda, J. J. Hansen, and P. Lind. 2002. Interpretation
of
the
gamma
interferon
test
for
diagnosis
of
subclinical
paratuberculosis in cattle. Clin. Diagn. Lab. Immunol. 9:453-460.
41. Kalis, C.H.J., M. T. Collins, J. W. Hesselink, and H. W. Barkema. 2003.
Specificity of two tests for the early diagnosis of bovine paratuberculosis
based on cell-mediated immunity: the Johnin skin test and the gamma
interferon assay. Vet. Microbiol. 97:73-86.
42. Karuppusamy, S., G. M. Kirby, L. Mutharia, and B. N. Tripathi. 2019.
An updata on Mycobacterium avium subspecies paratuberculosis
antigens and their role in the diagnosis of Johne’s disease. World
Journal of Microbiology and Biotechnology 35:120
43. Kathaperumal, K., V. Kumanan, S. McDonough, L. H. Chen, S. U. Park,
M. S. S. Moreira, B. Akey, J. Huntley, C. F. Chang, and Y. F. Chang.
2009. Evaluation of immune responses and protective efficacy in a goat
model following immunization with a cocktail of recombinant antigens
and a polyprotein of Mycobacterium avium subsp. paratuberculosis.
Vaccine. 27:123-135.
44. Kawamura, I., H. Tsukada, H. Yoshikawa, M. Fujita, K. Nomoto, and
M. Mitsuyama. 1992. IFN-gamma-producing ability as a possible
82
marker for the protective T cells against Mycobacterium bovis BCG in
mice. J. Immunol. 148:2887-2893.
45. Khalifeh, M. S., and J. R. Stabel. 2004. Effects of gamma interferon,
interleukin-10, and transforming growth factor beta on the survival of
Mycobacterium avium subsp. paratubeculosis in monocyte-derived
macrophages from naturally infected cattle. Infect. Immun. 72:19741982.
46. Koets, A. P., V. P. Rutten, M. de Boer, D. Bakker, P. Valentin-Weigand,
and W. van Eden. 2001. Differential changes in heat shock protein-,
lipoarabinomannan-,
and
purified
protein
derivative-specific
immunoglobulin G1 and G2 isotype responses during bovine
Mycobacterium avium subsp. paratuberculosis infection. Infect. Immun.
69:1492-1498.
47. Kralik, P., R. Pribylova-Dziedzinska, A. Kralova, K. Kovarcik, and I.
Slana. 2014. Evidence of passive faecal shedding of Mycobacterium
avium subsp. paratuberculosis in a Limousin cattle herd. Vet. J. 201:9194.
48. Kunser, D. J. 2005. Mechanisms of mycobacterial persistence in
tuberculosis. Clin. Immunol. 114:239-247.
49. Kwong, L. S., J. C. Hope, M. L. Thom, P. Sopp, S. Duggan, G. P.
Bembridge, and C. J. Howard. 2002. Development of an Elisa for bovine
IL-10. Vet. Immunol. Immunopathol. 85:213-223.
50. Li, LL., J. P. Bannantine, Q. Zhang, A. Amonsin, B. J. May, D. Alt, N.
Banerji, S. Kanjilal, and V. Kapur. 2005. The complete genome sequence
of Mycobacterium avium subspecies paratuberculosis. Proc. Natl. Acad.
83
Sci. U.S.A. 102:12344-12349.
51. Li, Y., E. miltner, M. Wu, M. Petrofsky, and L. E. Bermudez. 2005. A
Mycobacterium avium PPE gene is associated with the ability of the
bacterium to grow in macrophages and virulence in mice. Cell.
Microbiol. 7:539-548.
52. Livak, K. J., and T. D. Schmittgen. 2001. Analysis of relative gene
expression date using real-time quantitative PCR and the 2(-Delta
Delta C(T)) method. Method. 25:402-408.
53. Lombard, J. E., I. A. Gardner, S. R. Jafarzadeh, C. P. Fossler, B. Harris,
R. T. Capsel, B. A. Wagner, and W. O. Johnson. 2013. Herd-level
prevalence of Mycobacterium avium subsp. paratuberculosis infection
in United States dairy herds in 2007. Prev. Vet. Med. 108:234-238.
54. Lundegaard, C., O. Lund, C. Kesmir, S. Brunak, and M. Nielsen. 2007.
Modeling the adaptive immune system: predictions and simulations.
Bioinformatics. 23:3265-3275.
55. Magombedze, G, C. N. Ngonghala, and C. Lanzas. 2013. Evaluation
[corrected] of the "Iceberg Phenomenon" in Johne's disease through
mathematical modelling. PLoS One 8:e76636.
56. McDonald, W. L., S. E. Ridge, A. F. Hope, and R. J. Condron. 1999.
Evaluation diagnostic tests for Johne’s disease in young cattle. Aust.
Vet. J. 77:113-119.
57. Mikkelsen, H., C. Aagaard, S. S. Nielsen and G. Jungerson. 2011.
Review of Mycobacterium avium subsp. paratuberculosis antigen
candidates with diagnostic potential. Vet. Microbiol. 152:1-20.
58. Miller, H., J. Zhang, R. Kuolee, G. B. Patel, and W. Chen. 2007.
84
Intestinal
cells:
the
fallible
sentinels?
World
Journal
of
Gastroenterology. 13:1477-1486.
59. Momotani, E., D. L. Whipple, A. B. Thiermann, and N. F. Cheville. 1988.
Role of M cells and macrophages in the entrance of Mycobacterium
paratuberculosis onto domes of ileal Peyer’s patches in calves. Vet.
Pathol. 25:131-137.
60. Monteiro, L., D. Bonnemaison, A. Vekris, K. G. Petry, J. Bonnet, R.
Vidal, J. Cabrita, and F. Megraud. 1997. Complex polysaccharides as
PCR inhibitors in feces: Helicobacter pylori model. Journal of Clinical
Microbiology 35:995-998.
61. Motiwala, A. S., H. K. Janagama, M. L. Paustian, X. Zhu, J. P.
Bannantine, V. Kapur, and S. Sreevatsan. 2006. Comparative
transcriptional analysis of human macrophages exposed to animal and
human isolates of Mycobacterium avium subspecies paratuberculosis
with diverse genotypes. Infect. Immun. 74:6046-6056.
62. Murakami, K., A. Uchiyama, T. Kokuho, Y. Mori, H. Sentsui, T. Yada,
M. Tanigawa, A. Kuwano, H. Nagaya, S. Ishiyama, H. Kaki, Y.
Yokomizo, and S. Inumaru. 2001. Production of biologically active
recombinant bovine interferon-gamma by two different baculovirus
gene expression systems using insect cells and silkworm larvae.
Cytokine 13:18-24.
63. Navarro-Gonzalez, N., C. Fourichon, P. Blanquefort, A. Delafosse, A.
Joly, D. Ngwa-Mbot, F. Biet, D. Boichard, L. Schiber, L. Journaux, E.
Meens, and R. Guatteo. 2019. Longitudinal study of Mycobacterium
avium ssp. paratuberculosis fecal shedding patterns and concurrent
85
serological patterns in naturally infected dairy cattle. J. Dairy Sci.
102:9117-9137.
64. Newton, V., S. L. McKenna, and J. De Buck. 2009. Presence of PPE
proteins in Mycobacterium avium subsp. paratuberculosis and their
immunogenicity in cattle. Vet. Microbiol. 135:394-400.
65. Newton, V., and S. L. Mckenna. 2009. Presence of PPE proteins in
Mycobacterium avium subsp. paratuberculosis isolates and their
immunogenicity in cattle. Vet. Microbiol. 135:394-400.
66. Nielsen, S. S., and N. Toft. 2008. Ante mortem diagnosis of
paratuberculosis: A review of accuracies of ELISA, interferon-g assay
and faecal culture techniques. Veterinary Microbiology 129:217-235.
67. Okkels, L. M., I. Brock, F. Follmann, E. M. Agger, S. M. Arend, T. H. M.
Ottenhoff, F. Oftung, I. nkrands, and P. Andersen. 2003. PPE
protein(Rv3873)
from
DNA
segment
RD1
of
Mycobacterium
tuberculosis: strong recognition of both specific T-cell epitopes and
epitopes conserved within the PPE family. Infect. Immun. 71:6116-6123.
68. Olsen, I., L.J. Reitan, G. Holstad, and H. G. Wiker. 2000. Alkyl
hydroperoxide reductases C and D are major antigens constitutively
expressed by Mycobacterium avium subsp. paratuberculosis. Infect.
Immun. 68:801-808.
69. Olsen, I., P. Boysen, S. Kulberg, J. C. Hope, G. Jungersen, and A. K.
Storset. 2005. Bovine NK cells can produce gamma interferon in
response to the secreted mycobacterial proteins ESAT-6 and MPP14 but
not in response to MPB70. Infect. Immun. 73:5628-5635.
70. Olsen, I., and A. K. Storset. 2001. Innate IFN-gamma production in
86
cattle in response to MPP14, asecreted protein from Mycobacterium
avium subsp. paratuberculosis. Scand. J. Immunol. 54:306-313.
71. Park, S. J. and S. Y. Lee. 2003. Identification and characterization of
new enoyl coenzyme A hydratase involved in biosynthesis of mediumchain-length polyhydroxyalkanoates in recombinant Escherichia coli. J.
Bacteriol. 185:5391-5397.
72. Paustian, M. L., A. Amonsin, V. Kapur, and J. P. Bannantine. 2004.
Characterization of novel coding sequences specific to Mycobacterium
avium
subsp.
paratuberculosis:
implications
for
diagnosis
of
Johne’sdisease. J. Clin, Mycrobiol. 42:2675-2681.
73. Pillars, R. B., M. W. Bolton, and D. L. Grooms. 2011. Case-control study:
Productivity and longevity of dairy cows that tested positive for
infection with Mycobacterium avium ssp. paratuberculosis as heifers
compared to age-matched controls. J. Dairy Sci. 94:2825-2831.
74. Reichel, M. P., R. Kittelberger, M. E. Penrose, R. M. Meynell, D. Cousins,
T. Ellis, L. M. Mutharia, E. A. Sugden, A. H. Johns, and G. W. de Lisle.
1999. Comparison of serological tests and faecal culture for the
detection of Mycobacterium avium subsp. paratuberculosis infection in
cattle and analysis of the antigens involved. Vet. Microbiol. 66:135-150.
75. Ridge, S. E., I. R. Morgan, D. C. Sockett, M. T. Collins, R. J. Condron,
N. W. Skilbeck, and J. J. Webber. 1991. Comparison of the Johne’s
absorbed EIA and the complement-fixation test for the diagnosis of
Johne’s disease in cattle. Am. Vet. J. 68:253-257.
76. Rosseels, V., S. Marche, V. Roupie, M. Govaerts, J. Godfroid, K.
Walravens, and K. Huygen. 2006. Members of the 30- to 32- kilodalton
87
mycolyltransferase
family
(Ag85)
from
culture
filtrate
of
Mycobacterium avium subsp. paratuberculosis are immunodominant
Th1-type antigens recognized early upon infection in mice and cattle.
Infect. Immun. 74:202-212.
77. Secott, T. E., T. L. Lin, and C. C. Wu. 2004. Mycobacterium avium subsp.
paratuberculosis fibronectin attachment protein facilitates M-cell
targeting and invasion through a fibronectin bridge with host integrins.
Infect. immune. 72:3724-3732.
78. Semret. M., D. Bakker, N. Smart, I. Olsen, K. Haslov, and M. A. Behr.
2006. Genetic analysis of Mycobacterium avium complex strains used
for producing purified protein derivatives. Clin. Vaccine Immunol.
13:991-996.
79. Seubert, W., I. Lamberts, R. Kramer, and B. Ohly. 1968. On the
mechanism of malonyl-CoA-independent fatty acid synthesis. I. The
mechanism of elongation of long-chain fatty acids by acetyl-CoA.
Biochem. Biophys. Acta. 164:498-517.
80. Shimakata, T., Y. Fujita, and T. Kusaka. 1977. Acetyl-CoA-dependent
elongation of fatty acids in Mycobacterium smegmatis. J. Biochem.
82:725-732.
81. Shin, S. J., C. F. Chang, C. D. Chang, S. P. McDonough, B. Thompson,
H. S. Yoo, and Y. F. Chang. 2005. In vitro cellular immune responses to
recombinant antigens of Mycobacterium avium subsp. paratuberculosis.
Infect. Immun. 73:5074-5085.
82. Skeiky, Y. A. W., P. J. Ovendale, S. Jen, M. R. Alderson, D. C. Dillon, S.
Smith, C. B. Wilson, I. M. Orme, S. G. Reed, and A. Campos-Neto. 2000.
88
T cell expression cloning of a Mycobacterium tuberculosis gene
encoding a protective antigen associated with the early control of
infection. J. Immunol. 165:7140-7149.
83. Slavin Y. N., M. Bo, E. Caggiu, G. Srchi, G. Arru, H. Bach, and L. A.
Sechi. 2018. High levels of antibodies against PtpA and PknG secreted
by Mycobacterium avium ssp. paratuberculosis are present in
neuromyelitis pptica spectyum disorder and multiple sclerosis patients.
J. Neuroimmunol. 323:49-52.
84. Song, C. H., S. H. Lee, K. Lim, H. J. Kim, J. K. Park, T. H. Paik, and E.
K. Jo. 2003. Role of mitogen-activated protein kinase pathways in the
production of tumor necrosis factor-alpha, interleukin-10, and
monocyte chemotactic protein-1 by Mycobacterium tuberculosis
H37Rv-infected human monocytes. J. Clin. Immunol. 23:194-201.
85. Souza, C. D., O. A. Evanson, and D. J. Weiss. 2006. Mitogen activated
protein kinaseP38 pathway is an important component of the antiinflammatory
response
Mycobacterium
in
avium
subsp.
paratuberculosis-infected bovine monocytes. Microbiol. Pathogen.
41:59-66.
86. Souza, C. D., O. A. Evanson, and D. J. Weiss. 2008. Role of cell
membrane receptors in the suppression of monocyte anti-microbial
activity against Mycobacterium avium subsp. paratuberculosis.
Microbial. Pathogen. 44:215-223.
87. Stabel, J. R. 2007. Host responses to Mycobacterium avium subsp.
paratuberculosis: a complex arsenal. Anim. Health Res. Rev. 7:61-70.
88. Stabel. J. R. 2000. Transitions in immune responses to Mycobacterium
89
paratuberculosis. Vet. Microbiol. 77:465-473.
89. Sweeney, R. W. 1996. Transmission of paratuberculosis. Vet. Clin. North
Am. Food Anim. Pract. 12:305-312.
90. Wang J., J. Wakeham, R. Harkness, and Z. Xing. 1999. Macrophages
are a significant source of type 1 cytokines during mycobacterial
infection. J. Clin. Invest. 103:1023-1029.
91. Waters, W. R., J. R. Stabel, R. E. Sacco, J. A. Harp, B. A. Pesch., and M.
J. Wannemuehler. 1999. Antigen-sprcific B-cell unresponsiveness
induced by chronic Mycobacterium avium subsp. paratuberculosis
infection of cattle. Infect. Immun. 67:1593-1598.
92. Weiss, D. J., C. D. Souza, O. A. Evanson, M. Sanders, and M. Rutherford.
2008. Bovine monocyte TLR2 receptors differentially regulate the
intracellular fate of Mycobacterium avium subsp. paratuberculosis and
Mycobacterium avium subsp. avium. J. Leukoc. Biol. 83:48-55.
93. Weiss, D. J., O. A. Evanson, C. D. Souza, and M. S. Abrahamsen. 2005.
A critical role of interleukin-10 in the response of bovine macrophages
to Mycobacterium avium subsp. paratuberculosis. AJVR. 66:721-726.
94. Weiss, D. J., O. A. Evanson, M. Deng, and M. S. Abrahamsen. 2004.
Sequential patterns of gene expression by bovine monocyte-derived
macrophages associated with ingestion of mycobacterial organisms.
Microb. Pathog. 37:215-224.
95. Weiss, D. J., O. A. Evanson, and C. D. Souza. 2005. Expression of
interleukin-10 and suppressor of cytokine signaling-3 associated with
susceptibility of cattle to infection with Mycobacterium avium subsp.
paratuberculosis. Am. J. Vet. Res. 66:1114-1120.
90
96. Whipple, D.L., R.B. Le Febvre, R. E. Andrews, and A. B. Thiermann.
1987. Isolation and analysis of restriction endonuclease digestive
patterns of chromosomal DNA from Mycobacterium paratuberculosis
and other Mycobacterium species. J. Clin. Microbiol. 25:1511-1515.
97. Whitlock, R. H., and C. Buergelt. 1996. Preclinical and clinical
manifestations of paratuberculosis (including pathology). Vet. Clin.
North Am. Food Anim. Pract. 12:345-356.
98. Windsor, P. A., and R. J. Whittington. 2010. Evidence for age
susceptibility of cattle to Johne’s disease. The Veterinary Jounal.
184:37-44.
99. Yamada, H., T. Udagawa, S. Mizuno, K. Hiramatsu, and I. Sugawara.
2005. Newly designed primer sets available for evaluating various
cytokines and iNOS mRNA expression in guinea pig lung tissues byRTPCR. Exp. Anim. 54:163-172.
100. Yokomizo, Y., R.S. Merkal, and P. A. Lyle. 1983. Enzyme-linked
immunosorbent assay for detection of bovine immunoglobulin G1
antibody to a protoplasmic antigen of Mycobacterium paratuberculosis.
Am. J. Vet. Res. 44:2205-2207.
101. de Souza, G. D. S., A. B. F. Rodriguez, M. I. Romano, E. S. Ribeiro, W.
M. R. Oelemann, D. G. da Rovha, W. D. da Silva, E. B. Lasunskaia. 2018.
Identification of the Apa protein secreted by Mycobacterium avium
subsp. paratuberculosis as a novel fecal biomarker for Johne’s disease
in cattle. Pathog. Dis. 76:fty063.
91
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